CellNetworks - Most Important

2018

Protein Disaggregation in Multicellular Organisms

Nillegoda NB, Wentink AS, Bukau B

Trends Biochem Sci. 2018 Apr;43(4):285-300. doi: 10.1016/j.tibs.2018.02.003

2018

Inhibition of Endothelial Notch Signaling Impairs Fatty Acid Transport and Leads to Metabolic and Vascular Remodeling of the Adult Heart

Jabs M, Rose AJ, Lehmann LH, Taylor J, Moll I, Sijmonsma ...

Circulation. 2018 Jan 20. pii: CIRCULATIONAHA.117.029733. doi: 10.1161/CIRCULATIONAHA.117.029733

2018

A brave new world of RNA-binding proteins

Hentze MW, Castello A, Schwarzl T, Preiss T

Nat Rev Mol Cell Biol. 2018 Jan 17. doi: 10.1038/nrm.2017.130

2018

Sequential bottom-up assembly of mechanically stabilized synthetic cells by microfluidics

Weiss M, Frohnmayer JP, Benk LT, Haller B, Janiesch JW, H...

Nat Mater. 2018 Jan;17(1):89-96. doi: 10.1038/nmat5005.

2018

From Maps to Multi-dimensional Network Mechanisms of Mental Disorders

Braun U, Schaefer A, Betzel RF, Tost H, Meyer-Lindenberg ...

Neuron. 2018 Jan 3;97(1):14-31. doi: 10.1016/j.neuron.2017.11.007.

2018

From Maps to Multi-dimensional Network Mechanisms of Mental Disorders

Braun U, Schaefer A, Betzel RF, Tost H, Meyer-Lindenberg ...

Neuron. 2018 Jan 3;97(1):14-31. doi: 10.1016/j.neuron.2017.11.007.

2017

Molecular Mechanism of J-Domain-Triggered ATP Hydrolysis by Hsp70 Chaperones

Kityk R, Kopp J, Mayer MP

Mol Cell. 2017 Dec 27. pii: S1097-2765(17)30931-0. doi: 10.1016/j.molcel.2017.12.003.

2017

Visualizing the Assembly Pathway of Nucleolar Pre-60S Ribosomes

Kater L, Thoms M, Barrio-Garcia C, Cheng J, Ismail S, Ahm...

Cell. 2017 Dec 14;171(7):1599-1610.e14. doi: 10.1016/j.cell.2017.11.039.

2017

Mechanobiology by the numbers: a close relationship between biology and physics

Schwarz US

Nat Rev Mol Cell Biol. 2017 Dec;18(12):711-712. doi: 10.1038/nrm.2017.109.

2017

Fluorescence nanoscopy in cell biology

Sahl SJ, Hell SW, Jakobs S

Nat Rev Mol Cell Biol. 2017 Nov;18(11):685-701. doi: 10.1038/nrm.2017.71

2017

Cell mechanics: When tissues collide

Schwarz US, Ziebert F

Nat Mater. 2017 Oct;16(10):972-973. doi: 10.1038/nmat4988.

2017

Brain imaging tests for chronic pain: medical, legal and ethical issues and recommendations

Davis KD, Flor H, Greely HT, Iannetti GD, Mackey S, Plone...

Nat Rev Neurol. 2017 Oct;13(10):624-638. doi: 10.1038/nrneurol.2017.122

2017

A pathway from midcingulate cortex to posterior insula gates nociceptive hypersensitivity

Tan LL, Pelzer P, Heinl C, Tang W, Gangadharan V, Flor H,...

Nat Neurosci. 2017 Sep 18. doi: 10.1038/nn.4645

2017

Single-molecule FRET reveals the energy landscape of the full-length SAM-I riboswitch

Manz C, Kobitski AY, Samanta A, Keller BG, Jäschke A, Nie...

Nat Chem Biol. 2017 Sep 18. doi: 10.1038/nchembio.2476

2017

Solid-phase reverse transfection for intracellular delivery of functionally active proteins

Bulkescher R, Starkuviene V, Erfle H

Genome Res. 2017 Sep 5. doi: 10.1101/gr.215103.116

2017

Functional insights into pathogen biology from 3D electron microscopy

Cyrklaff M, Frischknecht F, Kudryashev M

FEMS Microbiol Rev. 2017 Aug 22. doi: 10.1093/femsre/fux041

2017

M3: an integrative framework for structure determination of molecular machines

Karaca E, Rodrigues JPGLM, Graziadei A, Bonvin AMJJ, Carl...

Nat Methods. 2017 Aug 14. doi: 10.1038/nmeth.4392

2017

Polylox barcoding reveals haematopoietic stem cell fates realized in vivo

Pei W, Feyerabend TB, Rössler J, Wang X, Postrach D, Busc...

Nature. 2017 Aug 24;548(7668):456-460. doi: 10.1038/nature23653.

2017

DNMT and HDAC inhibitors induce cryptic transcription start sites encoded in long terminal repeats

Brocks D, Schmidt CR, Daskalakis M, Jang HS, Shah NM, Li ...

Nat Genet. 2017 Jul;49(7):1052-1060. doi: 10.1038/ng.3889

2017

Minimum information about a single amplified genome (MISAG) and a metagenome-assembled genome (MIMAG) of bacteria and archaea

Bowers RM, Kyrpides NC, Stepanauskas R, Harmon-Smith M, D...

Nat Biotechnol. 2017 Aug 8;35(8):725-731. doi: 10.1038/nbt.3893

2017

Chromophore twisting in the excited state of a photoswitchable fluorescent protein captured by time-resolved serial femtosecond crystallography

Coquelle, N.; Sliwa, M.; Woodhouse, J.; Schirò, G.; Adam,...

Nature Chemistry. 2017 Jul 27. doi:10.1038/nchem.2853.

2017

The whole-genome landscape of medulloblastoma subtypes

Northcott PA, Buchhalter I, Morrissy A, Hovestadt V, Weis...

Nature. 2017 Jul 19;547(7663):311-317. doi: 10.1038/nature22973

2017

Profiling Ssb-Nascent Chain Interactions Reveals Principles of Hsp70-Assisted Folding

Döring K, Ahmed N, Riemer T, Suresh HG, Vainshtein Y, Hab...

Cell. 2017 Jul 13;170(2):298-311.e20. doi: 10.1016/j.cell.2017.06.038

2017

Single-Molecule Localization Microscopy in Eukaryotes

Sauer M, Heilemann M

Chem Rev. 2017 Jun 14;117(11):7478-7509. doi: 10.1021/acs.chemrev.6b00667

2017

Thiolutin is a zinc chelator that inhibits the Rpn11 and other JAMM metalloproteases

Lauinger L, Li J, Shostak A, Cemel IA, Ha N, Zhang Y, Mer...

Nat Chem Biol. 2017 Jul;13(7):709-714. doi: 10.1038/nchembio.2370.

2017

Broad-spectrum agents for flaviviral infections: dengue, Zika and beyond

Boldescu V, Behnam MAM, Vasilakis N, Klein CD

Nat Rev Drug Discov. 2017 May 5. doi: 10.1038/nrd.2017.33

2017

RETINOBLASTOMA RELATED1 mediates germline entry in Arabidopsis

Zhao X, Bramsiepe J, Van Durme M, Komaki S, Prusicki MA, ...

Science. 2017 Apr 28;356(6336). pii: eaaf6532. doi: 10.1126/science.aaf6532.

2017

Endoplasmic-reticulum-mediated microtubule alignment governs cytoplasmic streaming

Kimura K, Mamane A, Sasaki T, Sato K, Takagi J, Niwayama ...

Nat Cell Biol. 2017 Apr;19(4):399-406. doi: 10.1038/ncb3490.

2017

Prefrontal cortical control of a brainstem social behavior circuit

Franklin TB, Silva BA, Perova Z, Marrone L, Masferrer ME,...

Nat Neurosci. 2017 Feb;20(2):260-270. doi: 10.1038/nn.4470

2017

The nuclear pore complex: understanding its function through structural insight

Beck M, Hurt E

Nat Rev Mol Cell Biol. 2017 Feb;18(2):73-89. doi: 10.1038/nrm.2016.147.

2017

Structural plasticity and reorganisation in chronic pain

Kuner R, Flor H

Nat Rev Neurosci. 2017 Jan 20;18(2):113. doi: 10.1038/nrn.2017.5

2017

Defining the brain circuits involved in psychiatric disorders: IMI-NEWMEDS

Artigas F, Schenker E, Celada P, Spedding M, Lladó-Pelfor...

Nat Rev Drug Discov. 2017 Jan;16(1):1-2. doi: 10.1038/nrd.2016.205.

2017

Progress in imaging methods: insights gained into Plasmodium biology

De Niz M, Burda PC, Kaiser G, Del Portillo HA, Spielmann ...

Nat Rev Microbiol. 2017 Jan;15(1):37-54. doi: 10.1038/nrmicro.2016.158

2016

The structure and flexibility of conical HIV-1 capsids determined within intact virions

Mattei S, Glass B, Hagen WJ, Kräusslich HG, Briggs JA

Science. 2016 Dec 16;354(6318):1434-1437.

2016

Genetic code expansion for multiprotein complex engineering

Koehler C, Sauter PF, Wawryszyn M, Girona GE, Gupta K, La...

Nat Methods. 2016 Dec;13(12):997-1000. doi: 10.1038/nmeth.4032.

2016

Nuclear landscape of HIV-1 infection and integration

Lusic M, Siliciano RF

Nat Rev Microbiol. 2016 Dec 12. doi: 10.1038/nrmicro.2016.162

2016

Transcriptional programs that control expression of the autoimmune regulator gene Aire

Herzig Y, Nevo S, Bornstein C, Brezis MR, Ben-Hur S, Shke...

Nat Immunol. 2016 Dec 12. doi: 10.1038/ni.3638

2016

Temporal accumulation analysis provides simplified artifact-free analysis of membrane-protein nanoclusters

Spahn C, Herrmannsdörfer F, Kuner T, Heilemann M

Nat Methods. 2016 Nov 29;13(12):963-964. doi: 10.1038/nmeth.4065.

2016

Alternative modes of client binding enable functional plasticity of Hsp70

Mashaghi A, Bezrukavnikov S, Minde DP, Wentink AS, Kityk ...

Nature. 2016 Nov 17;539(7629):448-451. doi: 10.1038/nature20137

2016

Transient RNA-DNA Hybrids Are Required for Efficient Double-Strand Break Repair

Ohle C, Tesorero R, Schermann G, Dobrev N, Sinning I, Fis...

Cell. 2016 Nov 3;167(4):1001-1013.e7. doi: 10.1016/j.cell.2016.10.001

2016

Expanding the Circuitry of Pluripotency by Selective Isolation of Chromatin-Associated Proteins

Rafiee MR, Girardot C, Sigismondo G, Krijgsveld J

Mol Cell. 2016 Nov 3;64(3):624-635. doi: 10.1016/j.molcel.2016.09.019.

2016

Exploiting Noncovalent Interactions in an Imine-Based Covalent Organic Framework for Quercetin Delivery

Vyas VS, Vishwakarma M, Moudrakovski I, Haase F, Savasci ...

Adv Mater. 2016 Oct;28(39):8749-8754. doi: 10.1002/adma.201603006.

2016

Ecogenomics and potential biogeochemical impacts of globally abundant ocean viruses

Roux S1, Brum JR1, Dutilh BE2,3,4, Sunagawa S5, Duhaime M...

Nature. 2016 Sep 29;537(7622):689-693. doi: 10.1038/nature19366

2016

LOVTRAP: an optogenetic system for photoinduced protein dissociation

Wang H, Vilela M, Winkler A, Tarnawski M, Schlichting I, ...

Nat Methods. 2016 Sep;13(9):755-8. doi: 10.1038/nmeth.3926.

2016

The TRPM2 channel is a hypothalamic heat sensor that limits fever and can drive hypothermia

Song K, Wang H, Kamm GB, Pohle J, Reis FC, Heppenstall P,...

Science. 2016 Sep 23;353(6306):1393-1398.

2016

Acetylation-Dependent Control of Global Poly(A) RNA Degradation by CBP/p300 and HDAC1/2

Sharma S, Poetz F, Bruer M, Ly-Hartig TB, Schott J, Sérap...

Mol Cell. 2016 Sep 15;63(6):927-38. doi: 10.1016/j.molcel.2016.08.030.

2016

Vascular endothelial growth factor: a neurovascular target in neurological diseases

Lange C, Storkebaum E, de Almodóvar CR, Dewerchin M, Carm...

Nat Rev Neurol. 2016 Aug;12(8):439-54. doi: 10.1038/nrneurol.2016.88

2016

Global profiling of SRP interaction with nascent polypeptides

Schibich D, Gloge F, Pöhner I, Björkholm P, Wade RC, von ...

Nature. 2016 Aug 11;536(7615):219-23

2016

Tumour-cell-induced endothelial cell necroptosis via death receptor 6 promotes metastasis

Strilic B, Yang L, Albarrán-Juárez J, Wachsmuth L, Han K,...

Nature. 2016 Aug 11;536(7615):215-8

2016

Crystal structure of Zika virus NS2B-NS3 protease in complex with a boronate inhibitor

Lei J, Hansen G, Nitsche C, Klein CD, Zhang L, Hilgenfeld R

Science. 2016 Jul 29;353(6298):503-5. doi: 10.1126/science.aag2419

2016

Pre-assembled Nuclear Pores Insert into the Nuclear Envelope during Early Development

Hampoelz B, Mackmull MT, Machado P, Ronchi P, Bui KH, Sch...

Cell. 2016 Jul 28;166(3):664-78. doi: 10.1016/j.cell.2016.06.015

2016

Molecular biology: A surprise beginning for RNA

Höfer K, Jäschke A

Nature. 2016 Jul 21;535(7612):359-60

2016

An atomic model of HIV-1 capsid-SP1 reveals structures regulating assembly and maturation

Schur FK, Obr M, Hagen WJ, Wan W, Jakobi AJ, Kirkpatrick ...

Science. 2016 Jul 14. pii: aaf9620

2016

Architecture of the 90S Pre-ribosome: A Structural View on the Birth of the Eukaryotic Ribosome

Kornprobst M, Turk M, Kellner N, Cheng J, Flemming D, Koš...

Cell. 2016 Jul 14;166(2):380-93. doi: 10.1016/j.cell.2016.06.014

2016

In Vivo Tracking of Human Hematopoiesis Reveals Patterns of Clonal Dynamics during Early and Steady-State Reconstitution Phases

Biasco L, Pellin D, Scala S, Dionisio F, Basso-Ricci L, L...

Cell Stem Cell. 2016 Jul 7;19(1):107-19. doi: 10.1016/j.stem.2016.04.016

2016

Spatially segregated feedforward and feedback neurons support differential odor processing in the lateral entorhinal cortex

Leitner FC, Melzer S, Lütcke H, Pinna R, Seeburg PH, Helm...

Nat Neurosci. 2016 Jul;19(7):935-44. doi: 10.1038/nn.4303

2016

Data-driven hypothesis weighting increases detection power in genome-scale multiple testing

Ignatiadis N, Klaus B, Zaugg JB, Huber W

Nat Methods. 2016 Jul;13(7):577-80. doi: 10.1038/nmeth.3885

2016

Identifying multimodal signatures associated with symptom clusters: the example of the IMAGEMEND project

Frangou S, Schwarz E, Meyer-Lindenberg A, IMAGEMEND

World Psychiatry. 2016 Jun;15(2):179-80. doi: 10.1002/wps.20334.

2016

Altering the course of schizophrenia: progress and perspectives

Millan MJ, Andrieux A, Bartzokis G, Cadenhead K, Dazzan P...

Nat Rev Drug Discov. 2016 Jul;15(7):485-515. doi: 10.1038/nrd.2016.28.

2016

In Vivo Hepatic Reprogramming of Myofibroblasts with AAV Vectors as a Therapeutic Strategy for Liver Fibrosis

Rezvani M, Español-Suñer R, Malato Y, Dumont L, Grimm AA,...

Cell Stem Cell. 2016 Jun 2;18(6):809-16. doi: 10.1016/j.stem.2016.05.005

2016

Automated structure modeling of large protein assemblies using crosslinks as distance restraints

Ferber M, Kosinski J, Ori A, Rashid UJ, Moreno-Morcillo M...

Nat Methods. 2016 Jun;13(6):515-20. doi: 10.1038/nmeth.3838

2016

Automated structure modeling of large protein assemblies using crosslinks as distance restraints

Ferber M, Kosinski J, Ori A, Rashid UJ, Moreno-Morcillo M...

Nat Methods. 2016 Jun;13(6):515-20. doi: 10.1038/nmeth.3838

2016

Standardized benchmarking in the quest for orthologs

Altenhoff AM, Boeckmann B, Capella-Gutierrez S, Dalquen D...

Nat Methods. 2016 May;13(5):425-30. doi: 10.1038/nmeth.3830

2016

Molecular architecture of the inner ring scaffold of the human nuclear pore complex

Kosinski J, Mosalaganti S, von Appen A, Teimer R, DiGuili...

Science. 2016 Apr 15;352(6283):363-5. doi: 10.1126/science.aaf0643

2016

Molecular architecture of the inner ring scaffold of the human nuclear pore complex

Kosinski J, Mosalaganti S, von Appen A, Teimer R, DiGuili...

Science. 2016 Apr 15;352(6283):363-5. doi: 10.1126/science.aaf0643

2016

A new population of parvocellular oxytocin neurons controlling magnocellular neuron activity and inflammatory pain processing

Eliava M, Melchior M, Knobloch-Bollmann HS, Wahis J, da S...

NEURON 2016 Mar 16;89(6):1291-1304. doi: 10.1016/j.neuron.2016.01.041.

2016

SuReSim: simulating localization microscopy experiments from ground truth models

Venkataramani V, Herrmannsdörfer F, Heilemann M, Kuner T.

Nat Methods. 2016 Apr;13(4):319-21. doi: 10.1038/nmeth.3775. Epub 2016 Feb 29.

2016

Complex Interdependence Regulates Heterotypic Transcription Factor Distribution and Coordinates Cardiogenesis

Luna-Zurita L, Stirnimann CU, Glatt S, Kaynak BL, Thomas ...

Cell. 2016 Feb 25;164(5):999-1014. doi: 10.1016/j.cell.2016.01.004

2016

Myc Depletion Induces a Pluripotent Dormant State Mimicking Diapause

Scognamiglio R, Cabezas-Wallscheid N, Thier MC, Altamura ...

Cell. 2016 Feb 11;164(4):668-80. doi: 10.1016/j.cell.2015.12.033

2016

Plankton networks driving carbon export in the oligotrophic ocean

Guidi L, Chaffron S, Bittner L, Eveillard D, Larhlimi A, ...

Nature. 2016 Feb 10. doi: 10.1038/nature16942

2016

CYP3A5 mediates basal and acquired therapy resistance in different subtypes of pancreatic ductal adenocarcinoma

Noll EM, Eisen C, Stenzinger A, Espinet E, Muckenhuber A,...

Nat Med. 2016 Feb 8. doi: 10.1038/nm.4038

2016

Active medulloblastoma enhancers reveal subgroup-specific cellular origins

Lin CY, Erkek S, Tong Y, Yin L, Federation AJ, Zapatka M,...

Nature. 2016 Feb 4;530(7588):57-62. doi: 10.1038/nature16546

2016

In vitro cancer cell-ECM interactions inform in vivo cancer treatment

Holle AW, Young JL, Spatz JP

Adv Drug Deliv Rev. 2016 Feb 1;97:270-9. doi: 10.1016/j.addr.2015.10.007

2016

Femtosecond and nanometre visualization of structural dynamics in superheated nanoparticles

Gorkhover T, Schorb S, Coffee R, Adolph M, Foucar L, Rupp...

Nat Photonics. 2016 Jan 25; 10, 93–97, doi:10.1038/nphoton.2015.264.

2016

Genetics. IRES unplugged

Gebauer F, Hentze MW

Science. 2016 Jan 15;351(6270):228. doi: 10.1126/science.aad8540

2016

Identification and validation of biomarkers for autism spectrum disorders

Loth E, Spooren W, Ham LM, Isaac MB, Auriche-Benichou C, ...

Nat Rev Drug Discov. 2016 Jan;15(1):70-3. doi: 10.1038/nrd.2015.7.

2016

Apolipoprotein E Mediates Evasion From Hepatitis C Virus Neutralizing Antibodies

Fauvelle C, Felmlee DJ, Crouchet E, Lee J, Heydmann L, Le...

Gastroenterology. 2016 Jan;150(1):206-217.e4. doi: 10.1053/j.gastro.2015.09.014

2015

Molecular structures of unbound and transcribing RNA polymerase III

Hoffmann NA, Jakobi AJ, Moreno-Morcillo M, Glatt S, Kosin...

Nature. 2015 Dec 10;528(7581):231-6. doi: 10.1038/nature16143

2015

Inverted light-sheet microscope for imaging mouse pre-implantation development

Strnad P, Gunther S, Reichmann J, Krzic U, Balazs B, de M...

Nat Methods. 2015 Dec 14. doi: 10.1038/nmeth.3690. [Epub ahead of print]

2015

Inverted light-sheet microscope for imaging mouse pre-implantation development

Strnad P, Gunther S, Reichmann J, Krzic U, Balazs B, de M...

Nat Methods. 2015 Dec 14. doi: 10.1038/nmeth.3690. [Epub ahead of print]

2015

Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota

Forslund K, Hildebrand F, Nielsen T, Falony G, Le Chateli...

Nature. 2015 Dec 10;528(7581):262-6. doi: 10.1038/nature15766

2015

Microscopy-Based High-Content Screening

Boutros M, Heigwer F, Laufer C

Cell. 2015 Dec 3;163(6):1314-25. doi: 10.1016/j.cell.2015.11.007

2015

Brain tumour cells interconnect to a functional and resistant network

Osswald M, Jung E, Sahm F, Solecki G, Venkataramani V, Bl...

Nature. 2015 Dec 3;528(7580):93-8. doi: 10.1038/nature16071

2015

Thermal proteome profiling monitors ligand interactions with cellular membrane proteins

Reinhard FB, Eberhard D, Werner T, Franken H, Childs D, D...

Nat Methods. 2015 Dec;12(12):1129-31. doi: 10.1038/nmeth.3652

2015

NEMO Prevents Steatohepatitis and Hepatocellular Carcinoma by Inhibiting RIPK1 Kinase Activity-Mediated Hepatocyte Apoptosis

Kondylis V, Polykratis A, Ehlken H, Ochoa-Callejero L, St...

Cancer Cell. 2015 Nov 9;28(5):582-598. doi: 10.1016/j.ccell.2015.10.001

2015

Operon structure and cotranslational subunit association direct protein assembly in bacteria

Shieh YW, Minguez P, Bork P, Auburger JJ, Guilbride DL, K...

Science. 2015 Nov 6;350(6261):678-80. doi: 10.1126/science.aac8171

2015

DNA methylome analysis in Burkitt and follicular lymphomas identifies differentially methylated regions linked to somatic mutation and transcriptional control

Kretzmer H, Bernhart SH, Wang W, Haake A, Weniger MA, Ber...

Nat Genet. 2015 Nov;47(11):1316-25. doi: 10.1038/ng.3413

2015

The systematic analysis of protein-lipid interactions comes of age

Saliba AE, Vonkova I, Gavin AC

Nat Rev Mol Cell Biol. 2015 Dec;16(12):753-61. doi: 10.1038/nrm4080

2015

Direct observation of ultrafast collective motions in CO myoglobin upon ligand dissociation

Barends TR, Foucar L, Ardevol A, Nass K, Aquila A, Botha ...

Science. 2015 Oct 23;350(6259):445-50. doi: 10.1126/science.aac5492

2015

Plasticity of an Ultrafast Interaction between Nucleoporins and Nuclear Transport Receptors

Milles S, Mercadante D, Aramburu IV, Jensen MR, Banterle ...

Cell. 2015 Oct 22;163(3):734-45. doi: 10.1016/j.cell.2015.09.047. Epub 2015 Oct 8.

2015

η-Secretase processing of APP inhibits neuronal activity in the hippocampus

Willem M, Tahirovic S, Busche MA, Ovsepian SV, Chafai M, ...

Nature. 2015 Oct 15;526(7573):443-7. doi: 10.1038/nature14864

2015

Architecture of the fungal nuclear pore inner ring complex

Stuwe T, Bley CJ, Thierbach K, Petrovic S, Schilbach S, M...

Science. 2015 Oct 2;350(6256):56-64. doi: 10.1126/science.aac9176

2015

In situ structural analysis of the human nuclear pore complex

von Appen A, Kosinski J, Sparks L, Ori A, DiGuilio AL, Vo...

Nature. 2015 Oct 1;526(7571):140-3. doi: 10.1038/nature15381

2015

Inflammation-Induced Emergency Megakaryopoiesis Driven by Hematopoietic Stem Cell-like Megakaryocyte Progenitors

Haas S, Hansson J, Klimmeck D, Loeffler D, Velten L, Ucke...

Cell Stem Cell. 2015 Oct 1;17(4):422-34. doi: 10.1016/j.stem.2015.07.007. Epub 2015 Aug 20.

2015

Regulation of mitochondrial morphology and function by stearoylation of TFR1

Senyilmaz D, Virtue S, Xu X, Tan CY, Griffin JL, Miller A...

Nature. 2015 Sep 3;525(7567):124-8. doi: 10.1038/nature14601. Epub 2015 Jul 27.

2015

A background Ca2+ entry pathway mediated by TRPC1/TRPC4 is critical for development of pathological cardiac remodelling

Camacho Londoño JE, Tian Q, Hammer K, Schröder L, Camacho...

Eur Heart J. 2015 Sep 1;36(33):2257-66. doi: 10.1093/eurheartj/ehv250

2015

Niche appropriation by Drosophila intestinal stem cell tumours

Patel PH, Dutta D, Edgar BA

Nat Cell Biol. 2015 Sep;17(9):1182-92. doi: 10.1038/ncb3214.

2015

Ultrafast, temporally stochastic STED nanoscopy of millisecond dynamics

Schneider J, Zahn J, Maglione M, Sigrist SJ, Marquard J, ...

Nat Methods. 2015 Sep;12(9):827-30. doi: 10.1038/nmeth.3481

2015

Single-cell transcriptome analysis reveals coordinated ectopic gene-expression patterns in medullary thymic epithelial cells

Brennecke P, Reyes A, Pinto S, Rattay K, Nguyen M, Küchle...

Nat Immunol. 2015 Sep;16(9):933-41. doi: 10.1038/ni.3246

2015

The exosome is recruited to RNA substrates through specific adapter proteins

Thoms M, Thomson E, Baßler J, Gnädig M, Griesel S, Hurt E

Cell. 2015 Aug 27;162(5):1029-38. doi: 10.1016/j.cell.2015.07.060.

2015

Genetic Control of Chromatin States in Humans Involves Local and Distal Chromosomal Interactions

Grubert F, Zaugg JB, Kasowski M, Ursu O, Spacek DV, Marti...

Cell. 2015 Aug 27;162(5):1051-65. doi: 10.1016/j.cell.2015.07.048

2015

Unravelling Spinal Circuits of Pain and Mechanical Allodynia

Gangadharan V, Kuner R

Neuron. 2015 Aug 19;87(4):673-5. doi: 10.1016/j.neuron.2015.08.013

2015

Crucial HSP70 co-chaperone complex unlocks metazoan protein disaggregation

Nillegoda NB, Kirstein J, Szlachcic A, Berynskyy M, Stank...

Nature (published online 5 August 2015), doi:10.1038/nature14884

2015

Modulation of Presynaptic Release Probability by the Vertebrate-Specific Protein Mover

Körber C, Horstmann H, Venkataramani V, Herrmannsdörfer F...

Neuron. 2015 Aug 5;87(3):521-33. doi: 10.1016/j.neuron.2015.07.001. Epub 2015 Jul 23.

2015

VESICULAR TRANSPORT. A structure of the COPI coat and the role of coat proteins in membrane vesicle assembly

Dodonova SO, Diestelkoetter-Bachert P, von Appen A, Hagen...

Science. 2015 Jul 10;349(6244):195-8. doi: 10.1126/science.aab1121

2015

A Conserved Circular Network of Coregulated Lipids Modulates Innate Immune Responses

Köberlin MS, Snijder B, Heinz LX, Baumann CL, Fauster A, ...

Cell. 2015 Jul 2;162(1):170-83. doi: 10.1016/j.cell.2015.05.051

2015

Segregation versus colocalization: orthogonally functionalized binary micropatterned substrates regulate the molecular distribution in focal adhesions

Guasch J, Conings B, Neubauer S, Rechenmacher F, Ende K, ...

Adv Mater. 2015 Jul 1;27(25):3737-47. doi: 10.1002/adma.201500900

2015

BRAIN NETWORKS. Correlated gene expression supports synchronous activity in brain networks

Richiardi J, Altmann A, Milazzo AC, Chang C, Chakravarty ...

Science. 2015 Jun 12;348(6240):1241-4. doi: 10.1126/science.1255905

2015

When local poverty is more important than your income: Mental health in minorities in inner cities

Rapp MA, Kluge U, Penka S, Vardar A, Aichberger MC, Mundt...

World Psychiatry. 2015 Jun;14(2):249-50. doi: 10.1002/wps.20221.

2015

A Functional Role for VEGFR1 Expressed in Peripheral Sensory Neurons in Cancer Pain

Selvaraj D, Gangadharan V, Michalski CW, Kurejova M, Stös...

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Deichmann A, Hacein-Bey-Abina S, Schmidt M, Garrigue A, B...

J Clin Invest. 2007 Aug;117(8):2225-32.

2007

Molecular basis for the functional interaction of dynein light chain with the nuclear pore complex

Stelter P, Kunze R, Flemming D, Höpfner D, Diepholz M, Ph...

Nat Cell Biol. 2007 Jul;9(7):788-96.

2007

Maximal chromosome compaction occurs by axial shortening in anaphase and depends on Aurora kinase.

Mora-Bermúdez F, Gerlich D, Ellenberg J.

Nat Cell Biol. 2007 Jul;9(7):822-31

2007

Trawler: de novo regulatory motif discovery pipeline for chromatin immunoprecipitation

Ettwiller L, Paten B, Ramialison M, Birney E, Wittbrodt J

Nat Methods. 2007 Jul;4(7):563-5

2007

Systematic discovery of in vivo phosphorylation networks

Linding R, Jensen LJ, Ostheimer GJ, van Vugt MA, Jørgense...

Cell. 2007 Jun 29;129(7):1415-1426. doi: 10.1016/j.cell.2007.05.052

2007

Wnt induces LRP6 signalosomes and promotes dishevelled-dependent LRP6 phosphorylation.

Bilic J, Huang YL, Davidson G, Zimmermann T, Cruciat CM, ...

Science. 2007 Jun 15;316(5831):1619-22.

2007

Nuclear export of ribosomal 60S subunits by the general mRNA export receptor Mex67-Mtr2

Yao W, Roser D, Köhler A, Bradatsch B, Bassler J, Hurt E

Mol Cell. 2007 Apr 13;26(1):51-62

2007

Ca2+ channel blockers reverse iron overload by a new mechanism via divalent metal transporter-1.

Ludwiczek S, Theurl I, Muckenthaler MU, Jakab M, Mair SM,...

Nat Med. 2007 Apr;13(4):448-54.

2007

Modulation of the immunological synapse: a key to HIV-1 pathogenesis?

Fackler OT, Alcover A, Schwartz O.

Nat Rev Immunol. 2007 Apr;7(4):310-7.

2007

Quantitative phylogenetic assessment of microbial communities in diverse environments.

von Mering C, Hugenholtz P, Raes J, Tringe SG, Doerks T, ...

Science 315(5815):1126-1130. doi: 10.1126/science.1133420

2007

Gadd45a promotes epigenetic gene activation by repair-mediated DNA demethylation.

Barreto G, Schäfer A, Marhold J, Stach D, Swaminathan SK,...

Nature. 2007 Feb 8;445(7128):671-5.

2007

M-domains couple the ClpB threading motor with the DnaK chaperone activity

Haslberger T, Weibezahn J, Zahn R, Lee S, Tsai FT, Bukau ...

Mol Cell. 2007 Jan 26;25(2):247-60.

2007

Cdkn1a deletion improves stem cell function and lifespan of mice with dysfunctional telomeres without accelerating cancer formation.

Choudhury AR, Ju Z, Djojosubroto MW, Schienke A, Lechel A...

Nat Genet. 2007 Jan;39(1):99-105.

2007

Direct monitoring of formation and dissociation of individual metal complexes by single-molecule fluorescence spectroscopy

Kiel A, Kovacs J, Mokhir A, Krämer R, Herten DP

Angew Chem Int Ed Engl. 2007 Apr 27;46(18):3363-3366. doi: 10.1002/anie.200604965

2006

Following the signal sequence from ribosomal tunnel exit to signal recognition particle

Halic M, Blau M, Becker T, Mielke T, Pool MR, Wild K, Sin...

Nature. 2006 Nov 23;444(7118):507-11

2006

Individual cell migration serves as the driving force for optic vesicle evagination.

Rembold M, Loosli F, Adams RJ, Wittbrodt J.

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2006

High-throughput RNAi screening by time-lapse imaging of live human cells

Neumann B, Held M, Liebel U, Erfle H, Rogers P, Pepperkok...

Nat Methods. 2006 May;3(5):385-90

2006

Vaccinia virus-induced cell motility requires F11L-mediated inhibition of RhoA signaling

Valderrama F, Cordeiro JV, Schleich S, Frischknecht F, Way M

Science. 2006 Jan 20;311(5759):377-81

2005

IKK mediates ischemia-induced neuronal death

Herrmann O, Baumann B, de Lorenzi R, Muhammad S, Zhang W,...

Nat Med. 2005 Dec;11(12):1322-9.

2000

A complex of N-WASP and WIP integrates signalling cascades that lead to actin polymerization

Moreau V, Frischknecht F, Reckmann I, Vincentelli R, Rabu...

Nat Cell Biol. 2000 Jul;2(7):441-8

1999

Actin-based motility of vaccinia virus mimics receptor tyrosine kinase signalling

Frischknecht F, Moreau V, Röttger S, Gonfloni S, Reckmann...

Nature. 1999 Oct 28;401(6756):926-9

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