CellNetworks - Most Important

2017

Broad-spectrum agents for flaviviral infections: dengue, Zika and beyond

Boldescu V, Behnam MAM, Vasilakis N, Klein CD

Nat Rev Drug Discov. 2017 May 5. doi: 10.1038/nrd.2017.33

2017

Progress in imaging methods: insights gained into Plasmodium biology

De Niz M, Burda PC, Kaiser G, Del Portillo HA, Spielmann ...

Nat Rev Microbiol. 2017 Jan;15(1):37-54. doi: 10.1038/nrmicro.2016.158

2016

The structure and flexibility of conical HIV-1 capsids determined within intact virions

Mattei S, Glass B, Hagen WJ, Kräusslich HG, Briggs JA

Science. 2016 Dec 16;354(6318):1434-1437.

2016

Transcriptional programs that control expression of the autoimmune regulator gene Aire

Herzig Y, Nevo S, Bornstein C, Brezis MR, Ben-Hur S, Shke...

Nat Immunol. 2016 Dec 12. doi: 10.1038/ni.3638

2016

Nuclear landscape of HIV-1 infection and integration

Lusic M, Siliciano RF

Nat Rev Microbiol. 2016 Dec 12. doi: 10.1038/nrmicro.2016.162

2016

Alternative modes of client binding enable functional plasticity of Hsp70

Mashaghi A, Bezrukavnikov S, Minde DP, Wentink AS, Kityk ...

Nature. 2016 Nov 17;539(7629):448-451. doi: 10.1038/nature20137

2016

Transient RNA-DNA Hybrids Are Required for Efficient Double-Strand Break Repair

Ohle C, Tesorero R, Schermann G, Dobrev N, Sinning I, Fis...

Cell. 2016 Nov 3;167(4):1001-1013.e7. doi: 10.1016/j.cell.2016.10.001

2016

Global profiling of SRP interaction with nascent polypeptides

Schibich D, Gloge F, Pöhner I, Björkholm P, Wade RC, von ...

Nature. 2016 Aug 11;536(7615):219-23

2016

Tumour-cell-induced endothelial cell necroptosis via death receptor 6 promotes metastasis

Strilic B, Yang L, Albarrán-Juárez J, Wachsmuth L, Han K,...

Nature. 2016 Aug 11;536(7615):215-8

2016

Crystal structure of Zika virus NS2B-NS3 protease in complex with a boronate inhibitor

Lei J, Hansen G, Nitsche C, Klein CD, Zhang L, Hilgenfeld R

Science. 2016 Jul 29;353(6298):503-5. doi: 10.1126/science.aag2419

2016

Molecular biology: A surprise beginning for RNA

Höfer K, Jäschke A

Nature. 2016 Jul 21;535(7612):359-60

2016

An atomic model of HIV-1 capsid-SP1 reveals structures regulating assembly and maturation

Schur FK, Obr M, Hagen WJ, Wan W, Jakobi AJ, Kirkpatrick ...

Science. 2016 Jul 14. pii: aaf9620

2016

Architecture of the 90S Pre-ribosome: A Structural View on the Birth of the Eukaryotic Ribosome

Kornprobst M, Turk M, Kellner N, Cheng J, Flemming D, Koš...

Cell. 2016 Jul 14;166(2):380-93. doi: 10.1016/j.cell.2016.06.014

2016

Spatially segregated feedforward and feedback neurons support differential odor processing in the lateral entorhinal cortex

Leitner FC, Melzer S, Lütcke H, Pinna R, Seeburg PH, Helm...

Nat Neurosci. 2016 Jul;19(7):935-44. doi: 10.1038/nn.4303

2016

Data-driven hypothesis weighting increases detection power in genome-scale multiple testing

Ignatiadis N, Klaus B, Zaugg JB, Huber W

Nat Methods. 2016 Jul;13(7):577-80. doi: 10.1038/nmeth.3885

2016

Automated structure modeling of large protein assemblies using crosslinks as distance restraints

Ferber M, Kosinski J, Ori A, Rashid UJ, Moreno-Morcillo M...

Nat Methods. 2016 Jun;13(6):515-20. doi: 10.1038/nmeth.3838

2016

Molecular architecture of the inner ring scaffold of the human nuclear pore complex

Kosinski J, Mosalaganti S, von Appen A, Teimer R, DiGuili...

Science. 2016 Apr 15;352(6283):363-5. doi: 10.1126/science.aaf0643

2016

A new population of parvocellular oxytocin neurons controlling magnocellular neuron activity and inflammatory pain processing

Eliava M, Melchior M, Knobloch-Bollmann HS, Wahis J, da S...

NEURON 2016 Mar 16;89(6):1291-1304. doi: 10.1016/j.neuron.2016.01.041.

2016

SuReSim: simulating localization microscopy experiments from ground truth models

Venkataramani V, Herrmannsdörfer F, Heilemann M, Kuner T.

Nat Methods. 2016 Apr;13(4):319-21. doi: 10.1038/nmeth.3775. Epub 2016 Feb 29.

2016

Complex Interdependence Regulates Heterotypic Transcription Factor Distribution and Coordinates Cardiogenesis

Luna-Zurita L, Stirnimann CU, Glatt S, Kaynak BL, Thomas ...

Cell. 2016 Feb 25;164(5):999-1014. doi: 10.1016/j.cell.2016.01.004

2016

Myc Depletion Induces a Pluripotent Dormant State Mimicking Diapause

Scognamiglio R, Cabezas-Wallscheid N, Thier MC, Altamura ...

Cell. 2016 Feb 11;164(4):668-80. doi: 10.1016/j.cell.2015.12.033

2016

Plankton networks driving carbon export in the oligotrophic ocean

Guidi L, Chaffron S, Bittner L, Eveillard D, Larhlimi A, ...

Nature. 2016 Feb 10. doi: 10.1038/nature16942

2016

CYP3A5 mediates basal and acquired therapy resistance in different subtypes of pancreatic ductal adenocarcinoma

Noll EM, Eisen C, Stenzinger A, Espinet E, Muckenhuber A,...

Nat Med. 2016 Feb 8. doi: 10.1038/nm.4038

2016

Active medulloblastoma enhancers reveal subgroup-specific cellular origins

Lin CY, Erkek S, Tong Y, Yin L, Federation AJ, Zapatka M,...

Nature. 2016 Feb 4;530(7588):57-62. doi: 10.1038/nature16546

2016

In vitro cancer cell-ECM interactions inform in vivo cancer treatment

Holle AW, Young JL, Spatz JP

Adv Drug Deliv Rev. 2016 Feb 1;97:270-9. doi: 10.1016/j.addr.2015.10.007

2016

Genetics. IRES unplugged

Gebauer F, Hentze MW

Science. 2016 Jan 15;351(6270):228. doi: 10.1126/science.aad8540

2016

Apolipoprotein E Mediates Evasion From Hepatitis C Virus Neutralizing Antibodies

Fauvelle C, Felmlee DJ, Crouchet E, Lee J, Heydmann L, Le...

Gastroenterology. 2016 Jan;150(1):206-217.e4. doi: 10.1053/j.gastro.2015.09.014

2015

Molecular structures of unbound and transcribing RNA polymerase III

Hoffmann NA, Jakobi AJ, Moreno-Morcillo M, Glatt S, Kosin...

Nature. 2015 Dec 10;528(7581):231-6. doi: 10.1038/nature16143

2015

Inverted light-sheet microscope for imaging mouse pre-implantation development

Strnad P, Gunther S, Reichmann J, Krzic U, Balazs B, de M...

Nat Methods. 2015 Dec 14. doi: 10.1038/nmeth.3690. [Epub ahead of print]

2015

Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota

Forslund K, Hildebrand F, Nielsen T, Falony G, Le Chateli...

Nature. 2015 Dec 10;528(7581):262-6. doi: 10.1038/nature15766

2015

Microscopy-Based High-Content Screening

Boutros M, Heigwer F, Laufer C

Cell. 2015 Dec 3;163(6):1314-25. doi: 10.1016/j.cell.2015.11.007

2015

Brain tumour cells interconnect to a functional and resistant network

Osswald M, Jung E, Sahm F, Solecki G, Venkataramani V, Bl...

Nature. 2015 Dec 3;528(7580):93-8. doi: 10.1038/nature16071

2015

Thermal proteome profiling monitors ligand interactions with cellular membrane proteins

Reinhard FB, Eberhard D, Werner T, Franken H, Childs D, D...

Nat Methods. 2015 Dec;12(12):1129-31. doi: 10.1038/nmeth.3652

2015

Operon structure and cotranslational subunit association direct protein assembly in bacteria

Shieh YW, Minguez P, Bork P, Auburger JJ, Guilbride DL, K...

Science. 2015 Nov 6;350(6261):678-80. doi: 10.1126/science.aac8171

2015

DNA methylome analysis in Burkitt and follicular lymphomas identifies differentially methylated regions linked to somatic mutation and transcriptional control

Kretzmer H, Bernhart SH, Wang W, Haake A, Weniger MA, Ber...

Nat Genet. 2015 Nov;47(11):1316-25. doi: 10.1038/ng.3413

2015

The systematic analysis of protein-lipid interactions comes of age

Saliba AE, Vonkova I, Gavin AC

Nat Rev Mol Cell Biol. 2015 Dec;16(12):753-61. doi: 10.1038/nrm4080

2015

Direct observation of ultrafast collective motions in CO myoglobin upon ligand dissociation

Barends TR, Foucar L, Ardevol A, Nass K, Aquila A, Botha ...

Science. 2015 Oct 23;350(6259):445-50. doi: 10.1126/science.aac5492

2015

Plasticity of an Ultrafast Interaction between Nucleoporins and Nuclear Transport Receptors

Milles S, Mercadante D, Aramburu IV, Jensen MR, Banterle ...

Cell. 2015 Oct 22;163(3):734-45. doi: 10.1016/j.cell.2015.09.047. Epub 2015 Oct 8.

2015

η-Secretase processing of APP inhibits neuronal activity in the hippocampus

Willem M, Tahirovic S, Busche MA, Ovsepian SV, Chafai M, ...

Nature. 2015 Oct 15;526(7573):443-7. doi: 10.1038/nature14864

2015

Architecture of the fungal nuclear pore inner ring complex

Stuwe T, Bley CJ, Thierbach K, Petrovic S, Schilbach S, M...

Science. 2015 Oct 2;350(6256):56-64. doi: 10.1126/science.aac9176

2015

In situ structural analysis of the human nuclear pore complex

von Appen A, Kosinski J, Sparks L, Ori A, DiGuilio AL, Vo...

Nature. 2015 Oct 1;526(7571):140-3. doi: 10.1038/nature15381

2015

Inflammation-Induced Emergency Megakaryopoiesis Driven by Hematopoietic Stem Cell-like Megakaryocyte Progenitors

Haas S, Hansson J, Klimmeck D, Loeffler D, Velten L, Ucke...

Cell Stem Cell. 2015 Oct 1;17(4):422-34. doi: 10.1016/j.stem.2015.07.007. Epub 2015 Aug 20.

2015

Regulation of mitochondrial morphology and function by stearoylation of TFR1

Senyilmaz D, Virtue S, Xu X, Tan CY, Griffin JL, Miller A...

Nature. 2015 Sep 3;525(7567):124-8. doi: 10.1038/nature14601. Epub 2015 Jul 27.

2015

A background Ca2+ entry pathway mediated by TRPC1/TRPC4 is critical for development of pathological cardiac remodelling

Camacho Londoño JE, Tian Q, Hammer K, Schröder L, Camacho...

Eur Heart J. 2015 Sep 1;36(33):2257-66. doi: 10.1093/eurheartj/ehv250

2015

Niche appropriation by Drosophila intestinal stem cell tumours

Patel PH, Dutta D, Edgar BA

Nat Cell Biol. 2015 Sep;17(9):1182-92. doi: 10.1038/ncb3214.

2015

Ultrafast, temporally stochastic STED nanoscopy of millisecond dynamics

Schneider J, Zahn J, Maglione M, Sigrist SJ, Marquard J, ...

Nat Methods. 2015 Sep;12(9):827-30. doi: 10.1038/nmeth.3481

2015

Single-cell transcriptome analysis reveals coordinated ectopic gene-expression patterns in medullary thymic epithelial cells

Brennecke P, Reyes A, Pinto S, Rattay K, Nguyen M, Küchle...

Nat Immunol. 2015 Sep;16(9):933-41. doi: 10.1038/ni.3246

2015

The exosome is recruited to RNA substrates through specific adapter proteins

Thoms M, Thomson E, Baßler J, Gnädig M, Griesel S, Hurt E

Cell. 2015 Aug 27;162(5):1029-38. doi: 10.1016/j.cell.2015.07.060.

2015

Genetic Control of Chromatin States in Humans Involves Local and Distal Chromosomal Interactions

Grubert F, Zaugg JB, Kasowski M, Ursu O, Spacek DV, Marti...

Cell. 2015 Aug 27;162(5):1051-65. doi: 10.1016/j.cell.2015.07.048

2015

Unravelling Spinal Circuits of Pain and Mechanical Allodynia

Gangadharan V, Kuner R

Neuron. 2015 Aug 19;87(4):673-5. doi: 10.1016/j.neuron.2015.08.013

2015

Crucial HSP70 co-chaperone complex unlocks metazoan protein disaggregation

Nillegoda NB, Kirstein J, Szlachcic A, Berynskyy M, Stank...

Nature (published online 5 August 2015), doi:10.1038/nature14884

2015

Modulation of Presynaptic Release Probability by the Vertebrate-Specific Protein Mover

Körber C, Horstmann H, Venkataramani V, Herrmannsdörfer F...

Neuron. 2015 Aug 5;87(3):521-33. doi: 10.1016/j.neuron.2015.07.001. Epub 2015 Jul 23.

2015

VESICULAR TRANSPORT. A structure of the COPI coat and the role of coat proteins in membrane vesicle assembly

Dodonova SO, Diestelkoetter-Bachert P, von Appen A, Hagen...

Science. 2015 Jul 10;349(6244):195-8. doi: 10.1126/science.aab1121

2015

A Conserved Circular Network of Coregulated Lipids Modulates Innate Immune Responses

Köberlin MS, Snijder B, Heinz LX, Baumann CL, Fauster A, ...

Cell. 2015 Jul 2;162(1):170-83. doi: 10.1016/j.cell.2015.05.051

2015

Segregation versus colocalization: orthogonally functionalized binary micropatterned substrates regulate the molecular distribution in focal adhesions

Guasch J, Conings B, Neubauer S, Rechenmacher F, Ende K, ...

Adv Mater. 2015 Jul 1;27(25):3737-47. doi: 10.1002/adma.201500900

2015

BRAIN NETWORKS. Correlated gene expression supports synchronous activity in brain networks

Richiardi J, Altmann A, Milazzo AC, Chang C, Chakravarty ...

Science. 2015 Jun 12;348(6240):1241-4. doi: 10.1126/science.1255905

2015

A Functional Role for VEGFR1 Expressed in Peripheral Sensory Neurons in Cancer Pain

Selvaraj D, Gangadharan V, Michalski CW, Kurejova M, Stös...

Cancer Cell. 2015 Jun 8;27(6):780-96. doi: 10.1016/j.ccell.2015.04.017

2015

Ocean plankton. Determinants of community structure in the global plankton interactome

Lima-Mendez G, Faust K, Henry N, Decelle J, Colin S, Carc...

Science. 2015 May 22;348(6237):1262073. doi: 10.1126/science.1262073

2015

Ocean plankton. Environmental characteristics of Agulhas rings affect interocean plankton transport

Villar E, Farrant GK, Follows M, Garczarek L, Speich S, A...

Science. 2015 May 22;348(6237):1261447. doi: 10.1126/science.1261447

2015

Ocean plankton. Patterns and ecological drivers of ocean viral communities

Brum JR, Ignacio-Espinoza JC, Roux S, Doulcier G, Acinas ...

Science. 2015 May 22;348(6237):1261498. doi: 10.1126/science.1261498

2015

Ocean plankton. Eukaryotic plankton diversity in the sunlit ocean

de Vargas C, Audic S, Henry N, Decelle J, Mahé F, Logares...

Science. 2015 May 22;348(6237):1261605. doi: 10.1126/science.1261605

2015

Suppression of early hematogenous dissemination of human breast cancer cells to bone marrow by retinoic Acid-induced 2

Werner S, Brors B, Eick J, Marques E, Pogenberg V, Parret...

Cancer Discov. 2015 May;5(5):506-19. doi: 10.1158/2159-8290.CD-14-1042

2015

The serine protease inhibitor SerpinA3N attenuates neuropathic pain by inhibiting T cell-derived leukocyte elastase

Vicuña L, Strochlic DE, Latremoliere A, Bali KK, Simonett...

Nat Med. 2015 May;21(5):518-23. doi: 10.1038/nm.3852

2015

Clearance of persistent hepatitis C virus infection in humanized mice using a claudin-1-targeting monoclonal antibody

Mailly L, Xiao F, Lupberger J, Wilson GK, Aubert P, Duong...

Nat Biotechnol. 2015 Mar 23. doi: 10.1038/nbt.3179. [Epub ahead of print]

2015

NAD captureSeq indicates NAD as a bacterial cap for a subset of regulatory RNAs

Cahová H, Winz ML, Höfer K, Nübel K, Jäschke A

Nature. 2015 Mar 19;519(7543):374-7. doi: 10.1038/nature14020

2015

High-throughput fluorescence correlation spectroscopy enables analysis of proteome dynamics in living cells

Wachsmuth M, Conrad C, Bulkescher J, Koch B, Mahen R, Iso...

Nat Biotechnol. 2015 Mar 16. doi: 10.1038/nbt.3146. [Epub ahead of print]

2015

Nuclear architecture dictates HIV-1 integration site selection

Marini B, Kertesz-Farkas A, Ali H, Lucic B, Lisek K, Mang...

Nature. 2015 May 14;521(7551):227-31. doi: 10.1038/nature14226

2015

A molecular mechanotransduction pathway regulates collective migration of epithelial cells

Das T, Safferling K, Rausch S, Grabe N, Boehm H, Spatz JP

Nat Cell Biol. 2015 Feb 23. doi: 10.1038/ncb3115. [Epub ahead of print]

2015

GABA blocks pathological but not acute TRPV1 pain signals

Hanack C, Moroni M, Lima WC, Wende H, Kirchner M, Adelfin...

Cell. 2015 Feb 12;160(4):759-70. doi: 10.1016/j.cell.2015.01.022.

2015

Mutations in the SIX1/2 pathway and the DROSHA/DGCR8 miRNA microprocessor complex underlie high-risk blastemal type Wilms tumors

Wegert J, Ishaque N, Vardapour R, Geörg C, Gu Z, Bieg M, ...

Cancer Cell. 2015 Feb 9;27(2):298-311. doi: 10.1016/j.ccell.2015.01.002

2015

Iron regulatory protein 1 sustains mitochondrial iron loading and function in frataxin deficiency

Martelli A, Schmucker S, Reutenauer L, Mathieu JR, Peysso...

Cell Metab. 2015 Feb 3;21(2):311-22. doi: 10.1016/j.cmet.2015.01.010

2015

Orchestrating high-throughput genomic analysis with Bioconductor

Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carv...

Nat Methods. 2015 Feb;12(2):115-21. doi: 10.1038/nmeth.3252

2015

PIEZO2 is required for mechanotransduction in human stem cell-derived touch receptors

Schrenk-Siemens K, Wende H, Prato V, Song K, Rostock C, L...

Nat Neurosci. 2015 Jan;18(1):10-6. doi: 10.1038/nn.3894. Epub 2014 Dec 3

2015

Structure of the immature HIV-1 capsid in intact virus particles at 8.8 Å resolution

Schur FK, Hagen WJ, Rumlová M, Ruml T, Müller B, Kräussli...

Nature. 2015 Jan 22;517(7535):505-8. doi: 10.1038/nature13838. Epub 2014 Nov 2.

2015

Individual T helper cells have a quantitative cytokine memory

Helmstetter C, Flossdorf M, Peine M, Kupz A, Zhu J, Hegaz...

Immunity. 2015 Jan 20;42(1):108-22. doi: 10.1016/j.immuni.2014.12.018

2015

BAZ2A (TIP5) is involved in epigenetic alterations in prostate cancer and its overexpression predicts disease recurrence

Gu L, Frommel SC, Oakes CC, Simon R, Grupp K, Gerig CY, B...

Nat Genet. 2015 Jan;47(1):22-30. doi: 10.1038/ng.3165. Epub 2014 Dec 8

2014

Protein quality control at the inner nuclear membrane

Khmelinskii A, Blaszczak E, Pantazopoulou M, Fischer B, O...

Nature. 2014 Dec 17;516(7531):410-3. doi: 10.1038/nature14096.

2014

The Yeast ER-Intramembrane Protease Ypf1 Refines Nutrient Sensing by Regulating Transporter Abundance

Avci D, Fuchs S, Schrul B, Fukumori A, Breker M, Frumkin ...

Mol Cell. 2014 Dec 4;56(5):630-40. doi: 10.1016/j.molcel.2014.10.012. Epub 2014 Nov 13.

2014

A somatosensory circuit for cooling perception in mice

Milenkovic N, Zhao WJ, Walcher J, Albert T, Siemens J, Le...

Nat Neurosci. 2014 Nov;17(11):1560-6. doi: 10.1038/nn.3828. Epub 2014 Sep 28

2014

A memory system of negative polarity cues prevents replicative aging

Meitinger F, Khmelinskii A, Morlot S, Kurtulmus B, Palani...

Cell. 2014 Nov 20;159(5):1056-69. doi: 10.1016/j.cell.2014.10.014. Epub 2014 Nov 13

2014

Daclatasvir-like inhibitors of NS5A block early biogenesis of hepatitis C virus-induced membranous replication factories, independent of RNA replication

Berger C, Romero-Brey I, Radujkovic D, Terreux R, Zayas M...

Gastroenterology. 2014 Nov;147(5):1094-105.e25. doi: 10.1053/j.gastro.2014.07.019. Epub 2014 Jul 18

2014

Luminal signalling links cell communication to tissue architecture during organogenesis

Durdu S, Iskar M, Revenu C, Schieber N, Kunze A, Bork P, ...

Nature. 2014 Nov 6;515(7525):120-4. doi: 10.1038/nature13852. Epub 2014 Oct 22

2014

Structural biology: Enzyme-chromatin complex visualized

Müller J, Müller CW

Nature. 2014 Oct 30;514(7524):572-3. doi: 10.1038/514572a

2014

PSFj: know your fluorescence microscope

Theer P, Mongis C, Knop M

Nat Methods. 2014 Oct;11(10):981-2. doi: 10.1038/nmeth.3102

2014

Mitochondria tether protein trash to rejuvenate cellular environments

Mogk A, Bukau B

Cell. 2014 Oct 23;159(3):471-2. doi: 10.1016/j.cell.2014.10.007

2014

SUMOylation-dependent LRH-1/PROX1 interaction promotes atherosclerosis by decreasing hepatic reverse cholesterol transport

Stein S, Oosterveer MH, Mataki C, Xu P, Lemos V, Havinga ...

Cell Metab. 2014 Oct 7;20(4):603-13. doi: 10.1016/j.cmet.2014.07.023

2014

Photo-cross-linking and high-resolution mass spectrometry for assignment of RNA-binding sites in RNA-binding proteins

Kramer K, Sachsenberg T, Beckmann BM, Qamar S, Boon KL, H...

Nat Methods. 2014 Oct;11(10):1064-70. doi: 10.1038/nmeth.3092

2014

In vivo RNAi screening identifies a mechanism of sorafenib resistance in liver cancer

Rudalska R, Dauch D, Longerich T, McJunkin K, Wuestefeld ...

Nat Med. 2014 Oct;20(10):1138-46. doi: 10.1038/nm.3679. Epub 2014 Sep 14

2014

Identification of regulatory networks in HSCs and their immediate progeny via integrated proteome, transcriptome, and DNA Methylome analysis

Cabezas-Wallscheid N, Klimmeck D, Hansson J, Lipka DB, Re...

Cell Stem Cell. 2014 Oct 2;15(4):507-22. doi: 10.1016/j.stem.2014.07.005

2014

Biochemistry and Medicinal Chemistry of the Dengue Virus Protease

Nitsche C, Holloway S, Schirmeister T, Klein CD

Chem Rev. 2014 Sep 30. [Epub ahead of print]

2014

Uniquantal release through a dynamic fusion pore is a candidate mechanism of hair cell exocytosis

Chapochnikov NM, Takago H, Huang CH, Pangršič T, Khimich ...

Neuron. 2014 Sep 17;83(6):1389-403. doi: 10.1016/j.neuron.2014.08.003

2014

Axon-carrying dendrites convey privileged synaptic input in hippocampal neurons

Thome C, Kelly T, Yanez A, Schultz C, Engelhardt M, Cambr...

Neuron. 2014 Sep 17;83(6):1418-30. doi: 10.1016/j.neuron.2014.08.013. Epub 2014 Sep 4

2014

The symptom complex of familial sinus node dysfunction and myocardial noncompaction is associated with mutations in the HCN4 channel

Schweizer PA, Schröter J, Greiner S, Haas J, Yampolsky P,...

J Am Coll Cardiol. 2014 Aug 26;64(8):757-67. doi: 10.1016/j.jacc.2014.06.1155

2014

Nodal signalling determines biradial asymmetry in Hydra

Watanabe H, Schmidt HA, Kuhn A, Höger SK, Kocagöz Y, Laum...

Nature. 2014 Nov 6;515(7525):112-5. doi: 10.1038/nature13666

2014

Adding new dimensions: towards an integrative understanding of HIV-1 spread

Fackler OT, Murooka TT, Imle A, Mempel TR

Nat Rev Microbiol. 2014 Aug;12(8):563-74. doi: 10.1038/nrmicro3309

2014

An integrated catalog of reference genes in the human gut microbiome

Li J, Jia H, Cai X, Zhong H, Feng Q, Sunagawa S, Arumugam...

Nat Biotechnol. 2014 Aug;32(8):834-41. doi: 10.1038/nbt.2942. Epub 2014 Jul 6

2014

Identification and assembly of genomes and genetic elements in complex metagenomic samples without using reference genomes

Nielsen HB, Almeida M, Juncker AS, Rasmussen S, Li J, Sun...

Nat Biotechnol. 2014 Aug;32(8):822-8. doi: 10.1038/nbt.2939. Epub 2014 Jul 6

2014

Neuropsychosocial profiles of current and future adolescent alcohol misusers

Whelan R, Watts R, Orr CA, Althoff RR, Artiges E, Banasch...

Nature. 2014 Aug 14;512(7513):185-9. doi: 10.1038/nature13402. Epub 2014 Jul 2

2014

DENR-MCT-1 promotes translation re-initiation downstream of uORFs to control tissue growth

Schleich S, Strassburger K, Janiesch PC, Koledachkina T, ...

Nature. 2014 Aug 14;512(7513):208-12. doi: 10.1038/nature13401. Epub 2014 Jul 6

2014

Diverse intracellular pathogens activate type III interferon expression from peroxisomes

Odendall C, Dixit E, Stavru F, Bierne H, Franz KM, Durbin...

Nat Immunol. 2014 Aug;15(8):717-26. doi: 10.1038/ni.2915. Epub 2014 Jun 22

2014

Lipidomics: analysis of the lipid composition of cells and subcellular organelles by electrospray ionization mass spectrometry

Brügger B

Annu Rev Biochem. 2014;83:79-98. doi: 10.1146/annurev-biochem-060713-035324. Epub 2014 Mar 3

2014

Coexpressed auxiliary subunits exhibit distinct modulatory profiles on AMPA receptor function

Khodosevich K, Jacobi E, Farrow P, Schulmann A, Rusu A, Z...

Neuron. 2014 Aug 6;83(3):601-15. doi: 10.1016/j.neuron.2014.07.004. Epub 2014 Jul 24

2014

Resistance of Ferroportin to Hepcidin Binding causes Exocrine Pancreatic Failure and Fatal Iron Overload

Altamura S, Kessler R, Gröne HJ, Gretz, N, Hentze MW, Gal...

Cell Metabolism, Volume 20, Issue 2, 5 August 2014, Pages 359–367

2014

Monocytes activate natural killer cells via inflammasome-induced interleukin 18 in response to hepatitis C virus replication

Serti E, Werner JM, Chattergoon M, Cox AL, Lohmann V, Reh...

Gastroenterology. 2014 Jul;147(1):209-220.e3. doi: 10.1053/j.gastro.2014.03.046. Epub 2014 Mar 28

2014

Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma

Northcott PA, Lee C, Zichner T, Stütz AM, Erkek S, Kawauc...

Nature. 2014 Jul 24;511(7510):428-34. doi: 10.1038/nature13379. Epub 2014 Jun 22

2014

Imaging charge transfer in iodomethane upon x-ray photoabsorption

Erk B, Boll R, Trippel S, Anielski D, Foucar L, Rudek B, ...

Science. 2014 Jul 18;345(6194):288-91. doi: 10.1126/science.1253607. Epub 2014 Jul 17

2014

Serial transfer of single-cell-derived immunocompetence reveals stemness of CD8(+) central memory T cells

Graef P, Buchholz VR, Stemberger C, Flossdorf M, Henkel L...

Immunity. 2014 Jul 17;41(1):116-26. doi: 10.1016/j.immuni.2014.05.018

2014

Fluorogenic probes for live-cell imaging of the cytoskeleton

Lukinavičius G, Reymond L, D'Este E, Masharina A, Göttfer...

Nat Methods. 2014 Jul;11(7):731-3. doi: 10.1038/nmeth.2972

2014

Enhancer loops appear stable during development and are associated with paused polymerase

Ghavi-Helm Y, Klein FA, Pakozdi T, Ciglar L, Noordermeer ...

Published online in Nature, 2 July 2014. DOI: 10.1038/nature13417.

2014

Wnt-Fzd signaling sensitizes peripheral sensory neurons via distinct noncanonical pathways

Simonetti M, Agarwal N, Stösser S, Bali KK, Karaulanov E,...

Neuron. 2014 Jul 2;83(1):104-21. doi: 10.1016/j.neuron.2014.05.037

2014

Decoding the regulatory landscape of medulloblastoma using DNA methylation sequencing

Hovestadt V, Jones DT, Picelli S, Wang W, Kool M, Northco...

Nature. 2014 Jun 26;510(7506):537-41. doi: 10.1038/nature13268. Epub 2014 May 18

2014

RNA specificity and regulation of catalysis in the eukaryotic polynucleotide kinase Clp1

Dikfidan A, Loll B, Zeymer C, Magler I, Clausen T, Meinha...

Mol Cell. 2014 Jun 19;54(6):975-86. doi: 10.1016/j.molcel.2014.04.005. Epub 2014 May 8

2014

Human and mouse VEGFA-amplified hepatocellular carcinomas are highly sensitive to sorafenib treatment

Horwitz E, Stein I, Andreozzi M, Nemeth J, Shoham A, Papp...

Cancer Discov. 2014 Jun;4(6):730-43. doi: 10.1158/2159-8290.CD-13-0782. Epub 2014 Mar 31

2014

FHOD1 interaction with nesprin-2G mediates TAN line formation and nuclear movement

Kutscheidt S, Zhu R, Antoku S, Luxton GW, Stagljar I, Fac...

Nat Cell Biol. 2014 Jun 1. doi: 10.1038/ncb2981. [Epub ahead of print]

2014

Parvalbumin interneurons provide grid cell-driven recurrent inhibition in the medial entorhinal cortex

Buetfering C, Allen K, Monyer H

Nat Neurosci. 2014 May;17(5):710-8. doi: 10.1038/nn.3696. Epub 2014 Apr 6

2014

Inhibition of HCV replication by cyclophilin antagonists is linked to replication fitness and occurs by inhibition of membranous web formation

Madan V, Paul D, Lohmann V, Bartenschlager R

Gastroenterology. 2014 May;146(5):1361-72.e1-9. doi: 10.1053/j.gastro.2014.01.055. Epub 2014 Jan 31

2014

Border control--a membrane-linked interactome of Arabidopsis

Jones AM, Xuan Y, Xu M, Wang RS, Ho CH, Lalonde S, You CH...

Science. 2014 May 16;344(6185):711-6. doi: 10.1126/science.1251358

2014

SRP RNA remodeling by SRP68 explains its role in protein translocation

Grotwinkel JT, Wild K, Segnitz B, Sinning I

Science. 2014 Apr 4;344(6179):101-4. doi: 10.1126/science.1249094.

2014

Hippocampal synaptic plasticity, spatial memory and anxiety

Bannerman DM, Sprengel R, Sanderson DJ, McHugh SB, Rawlin...

Nat Rev Neurosci. 2014 Mar;15(3):181-92. doi: 10.1038/nrn3677

2014

Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition

Kool M, Jones DT, Jäger N, Northcott PA, Pugh TJ, Hovesta...

Cancer Cell. 2014 Mar 17;25(3):393-405. doi: 10.1016/j.ccr.2014.02.004

2014

Objective comparison of particle tracking methods

Chenouard N, Smal I, de Chaumont F, Maška M, Sbalzarini I...

Nat Methods. 2014 Mar;11(3):281-9. doi: 10.1038/nmeth.2808. Epub 2014 Jan 19

2014

Art and artifacts in single-molecule localization microscopy: beyond attractive images

Endesfelder U, Heilemann M

Nat Methods. 2014 Mar;11(3):235-8. doi: 10.1038/nmeth.2852

2014

Epigenomic alterations define lethal CIMP-positive ependymomas of infancy

Mack SC, Witt H, Piro RM, Gu L, Zuyderduyn S, Stütz AM, W...

Nature. 2014 Feb 27;506(7489):445-50. doi: 10.1038/nature13108. Epub 2014 Feb 19

2014

A quantitative liposome microarray to systematically characterize protein-lipid interactions

Saliba AE, Vonkova I, Ceschia S, Findlay GM, Maeda K, Tis...

Nat Methods. 2014 Jan;11(1):47-50. doi: 10.1038/nmeth.2734. Epub 2013 Nov 24

2014

Continuous throughput and long-term observation of single-molecule FRET without immobilization

Tyagi S, Vandelinder V, Banterle N, Fuertes G, Milles S, ...

Nat Methods. 2014 Jan 19. doi: 10.1038/nmeth.2809. [Epub ahead of print]

2014

A spatial accommodation by neighboring cells is required for organ initiation in Arabidopsis

Vermeer JE, von Wangenheim D, Barberon M, Lee Y, Stelzer ...

Science. 2014 Jan 10;343(6167):178-83. doi: 10.1126/science.1245871.

2014

Chaperone action at the single-molecule level

Mashaghi A, Kramer G, Lamb DC, Mayer MP, Tans SJ.

Chem Rev. 2014 Jan 8;114(1):660-76.

2013

Neuroscience: The highs and lows of memory

Allen K, Monyer H

Nature. 2013 Dec 12;504(7479):228-9. doi: 10.1038/504228a

2013

Integrated structural analysis of the human nuclear pore complex scaffold

Bui KH, von Appen A, Diguilio AL, Ori A, Sparks L, Mackmu...

Cell. 2013 Dec 5;155(6):1233-43. doi: 10.1016/j.cell.2013.10.055.

2013

Cell-to-cell expression variability followed by signal reinforcement progressively segregates early mouse lineages

Ohnishi Y, Huber W, Tsumura A, Kang M, Xenopoulos P, Kuri...

Nat Cell Biol. 2013 Dec 1. doi: 10.1038/ncb2881. [Epub ahead of print]

2013

Coupled GTPase and remodelling ATPase activities form a checkpoint for ribosome export

Matsuo Y, Granneman S, Thoms M, Manikas RG, Tollervey D, ...

Nature. 2013 November 17;published online 17 November 2013, doi:10.1038/nature12731

2013

GTP regulates the microtubule nucleation activity of γ-tubulin

Gombos L, Neuner A, Berynskyy M, Fava LL, Wade RC, Sachse...

Nat Cell Biol. 2013 Nov;15(11):1317-27. doi: 10.1038/ncb2863. Epub 2013 Oct 27

2013

Determinants of robustness in spindle assembly checkpoint signalling

Heinrich S, Geissen EM, Kamenz J, Trautmann S, Widmer C, ...

Nat Cell Biol. 2013 Nov;15(11):1328-39. doi: 10.1038/ncb2864.

2013

Cellular mechanosensing: Sharing the force.

Bausch AR, Schwarz US.

Nat Mater. 2013 Nov;12(11):948-9.

2013

Independent hypothalamic circuits for social and predator fear

Silva BA, Mattucci C, Krzywkowski P, Murana E, Illarionov...

Nat Neurosci. 2013 Nov 10. doi: 10.1038/nn.3573. [Epub ahead of print]

2013

Hydrogel micropillars with integrin selective peptidomimetic functionalized nanopatterned tops: a new tool for the measurement of cell traction forces transmitted through αvβ3- or α5β1-integrins

Rahmouni S, Lindner A, Rechenmacher F, Neubauer S, Sobahi...

Adv Mater. 2013 Nov 6;25(41):5869-74. doi: 10.1002/adma.201301338. Epub 2013 Aug 5

2013

Crystal structure of the 14-subunit RNA polymerase I

Fernández-Tornero C, Moreno-Morcillo M, Rashid UJ, Taylor...

Nature. 2013 Oct 31;502(7473):644-9. doi: 10.1038/nature12636

2013

Metagenomic species profiling using universal phylogenetic marker genes

Sunagawa S, Mende DR, Zeller G, Izquierdo-Carrasco F, Ber...

Nat. Methods 10(12):1196-1199. doi: 10.1038/nmeth.2693

2013

Directional tissue migration through a self-generated chemokine gradient

Donà E, Barry JD, Valentin G, Quirin C, Khmelinskii A, Ku...

Nature. 2013 Sep 25. doi: 10.1038/nature12635. [Epub ahead of print]

2013

Macrophage MicroRNA-155 Promotes Cardiac Hypertrophy and Failure

Heymans S, Corsten MF, Verhesen W, Carai P, van Leeuwen R...

Circulation. 2013 Sep 24;128(13):1420-32. doi: 10.1161/CIRCULATIONAHA.112.001357

2013

Connective tissue growth factor regulates interneuron survival and information processing in the olfactory bulb

Khodosevich K, Lazarini F, von Engelhardt J, Kaneko H, Ll...

Neuron. 2013 Sep 18;79(6):1136-51. doi: 10.1016/j.neuron.2013.07.011. Epub 2013 Aug 29

2013

STED nanoscopy combined with optical tweezers reveals protein dynamics on densely covered DNA

Heller I, Sitters G, Broekmans OD, Farge G, Menges C, Wen...

Nat Methods. 2013 Sep;10(9):910-6. doi: 10.1038/nmeth.2599

2013

High-Content siRNA Screen Reveals Global ENaC Regulators and Potential Cystic Fibrosis Therapy Targets

Almaça J, Faria D, Sousa M, Uliyakina I, Conrad C, Sirian...

Cell. 2013 Sep 12;154(6):1390-400. doi: 10.1016/j.cell.2013.08.045.

2013

Lentiviral hematopoietic stem cell gene therapy in patients with Wiskott-Aldrich syndrome

Aiuti A, Biasco L, Scaramuzza S, Ferrua F, Cicalese MP, B...

Science. 2013 Aug 23;341(6148):1233151. doi: 10.1126/science.1233151. Epub 2013 Jul 11

2013

Lentiviral hematopoietic stem cell gene therapy benefits metachromatic leukodystrophy

Biffi A, Montini E, Lorioli L, Cesani M, Fumagalli F, Pla...

Science. 2013 Aug 23;341(6148):1233158. doi: 10.1126/science.1233158. Epub 2013 Jul 11

2013

Signatures of mutational processes in human cancer

Alexandrov LB, Nik-Zainal S, Wedge DC, Aparicio SA, Behja...

Nature. 2013 Aug 22;500(7463):415-21. doi: 10.1038/nature12477. Epub 2013 Aug 14

2013

Physics of adherent cells

Ulrich S. Schwarz and Samuel A. Safran

Rev. Mod. Phys., 85:1327-1381, Aug 2013

2013

Nanoscopy with more than 100,000 'doughnuts'

Chmyrov A, Keller J, Grotjohann T, Ratz M, d'Este E, Jako...

Nat Methods. 2013 Aug;10(8):737-40. doi: 10.1038/nmeth.2556

2013

Interactome map uncovers phosphatidylserine transport by oxysterol-binding proteins

Maeda K, Anand K, Chiapparino A, Kumar A, Poletto M, Kaks...

Published online in Nature on 11 August 2013. DOI: 10.1038/nature12430.

2013

Nuclear pore scaffold structure analyzed by super-resolution microscopy and particle averaging

Szymborska A, de Marco A, Daigle N, Cordes VC, Briggs JA,...

Science. 2013 Aug 9;341(6146):655-8. doi: 10.1126/science.1240672

2013

Continued response off treatment after BRAF inhibition in refractory hairy cell leukemia

Dietrich S, Hüllein J, Hundemer M, Lehners N, Jethwa A, C...

J Clin Oncol. 2013 Jul 1;31(19):e300-3. doi: 10.1200/JCO.2012.45.9495. Epub 2013 May 20

2013

The molecular and structural basis of advanced antiviral therapy for hepatitis C virus infection

Bartenschlager R, Lohmann V, Penin F

Nat Rev Microbiol. 2013 Jul;11(7):482-96. doi: 10.1038/nrmicro3046. Epub 2013 Jun 10

2013

The neural basis of phantom limb pain

Flor H, Diers M, Andoh J

Trends Cogn Sci. 2013 Jul;17(7):307-8. doi: 10.1016/j.tics.2013.04.007. Epub 2013 Apr 19

2013

Structural basis of histone H2A-H2B recognition by the essential chaperone FACT

Hondele M, Stuwe T, Hassler M, Halbach F, Bowman A, Zhang...

Nature.

2013

Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma

Jones DT, Hutter B, Jäger N, Korshunov A, Kool M, Warnatz...

Nat Genet. 2013 Aug;45(8):927-32. doi: 10.1038/ng.2682

2013

Origin of monocytes and macrophages in a committed progenitor

Hettinger J, Richards DM, Hansson J, Barra MM, Joschki AK...

Nat. Immunol. 14(8):821-830. doi:10.1038/ni.2638

2013

Yes-associated protein up-regulates Jagged-1 and activates the Notch pathway in human hepatocellular carcinoma

Tschaharganeh DF, Chen X, Latzko P, Malz M, Gaida MM, Fel...

Gastroenterology. 2013 Jun;144(7):1530-1542.e12. doi: 10.1053/j.gastro.2013.02.009. Epub 2013 Feb 16

2013

SUMOylation - a regulatory protein modification in health and disease

Flotho F, Melchior F

Annu Rev Biochem. 2013;82:357-85. doi: 10.1146/annurev-biochem-061909-093311

2013

Roquin Promotes Constitutive mRNA Decay via a Conserved Class of Stem-Loop Recognition Motifs

Leppek K, Schott J, Reitter S, Poetz F, Hammond MC, Stoec...

Cell, Volume 153, Issue 4, 869-881, 9 May 2013, 10.1016/j.cell.2013.04.016

2013

Mapping genetic interactions in human cancer cells with RNAi and multiparametric phenotyping

Laufer C, Fischer B, Billmann M, Huber W, Boutros M

Nat Methods. 2013 May;10(5):427-31. doi: 10.1038/nmeth.2436

2013

Disparate individual fates compose robust CD8+ T cell immunity

Buchholz VR, Flossdorf M, Hensel I, Kretschmer L, Weissbr...

Science. 2013 May 3;340(6132):630-5. doi: 10.1126/science.1235454

2013

A Direct in vivo RNAi screen identifies MKK4 as a key regulator of liver regeneration

Wuestefeld T, Pesic M, Rudalska R, Dauch D, Longerich T, ...

Cell. 2013 Apr 11;153(2):389-401. doi: 10.1016/j.cell.2013.03.026

2013

New insights into the classification and nomenclature of cortical GABAergic interneurons

DeFelipe J, López-Cruz PL, Benavides-Piccione R, Bielza C...

Nat Rev Neurosci. 2013 Mar;14(3):202-16. doi: 10.1038/nrn3444

2013

Lentiviral vector-based insertional mutagenesis identifies genes associated with liver cancer

Ranzani M, Cesana D, Bartholomae CC, Sanvito F, Pala M, B...

Nat Methods. 2013 Feb;10(2):155-61. doi: 10.1038/nmeth.2331. Epub 2013 Jan 13

2013

SCFFbxw5 mediates transient degradation of actin remodeller Eps8 to allow proper mitotic progression

Werner A, Disanza A, Reifenberger N, Habeck G, Becker J, ...

Nat Cell Biol. 2013 Feb;15(2):179-88. doi: 10.1038/ncb2661

2013

Integrative genomic analyses reveal androgen-driven somatic alteration landscape in early-onset prostate cancer

Weischenfeldt J, Simon R, Feuerbach L, Schlangen K, Weich...

Cancer Cell. 2013 Feb 11;23(2):159-70. doi: 10.1016/j.ccr.2013.01.002.

2013

Factors that Determine the Antiviral Efficacy of HCV-Specific CD8+ T cells Ex Vivo

Seigel B, Bengsch B, Lohmann V, Bartenschlager R, Blum HE...

Gastroenterology.

2013

The IRP1-HIF-2α axis coordinates iron and oxygen sensing with erythropoiesis and iron absorption

Anderson SA, Nizzi CP, Chang YI, Deck KM, Schmidt PJ, Gal...

Cell Metab. 2013 Feb 5;17(2):282-90. doi: 10.1016/j.cmet.2013.01.007

2013

A near-infrared fluorophore for live-cell super-resolution microscopy of cellular proteins

Lukinavičius G, Umezawa K, Olivier N, Honigmann A, Yang G...

Nat Chem. 2013 Feb;5(2):132-9. doi: 10.1038/nchem.1546. Epub 2013 Jan 6.

2013

A near-infrared fluorophore for live-cell super-resolution microscopy of cellular proteins

Lukinavičius G, Umezawa K, Olivier N, Honigmann A, Yang G...

Nat Chem. 2013 Feb;5(2):132-9. doi: 10.1038/nchem.1546. Epub 2013 Jan 6.

2013

Natively inhibited Trypanosoma brucei cathepsin B structure determined by using an X-ray laser

Redecke L, Nass K, DePonte DP, White TA, Rehders D, Barty...

Science. 2013 Jan 11;339(6116):227-30. doi: 10.1126/science.1229663

2013

Nuclear Calcium Signaling in Spinal Neurons Drives a Genomic Program Required for Persistent Inflammatory Pain

Simonetti M, Hagenston AM, Vardeh D, Freitag HE, Mauceri ...

Neuron. 2013 Jan 9;77(1):43-57. doi: 10.1016/j.neuron.2012.10.037

2013

Genomic variation landscape of the human gut microbiome

Schloissnig S, Arumugam M, Sunagawa S, Mitreva M, Tap J, ...

Nature. 2013 Jan 3;493(7430):45-50. doi: 10.1038/nature11711

2012

TRPM4 cation channel mediates axonal and neuronal degeneration in experimental autoimmune encephalomyelitis and multiple sclerosis

Schattling B, Steinbach K, Thies E, Kruse M, Menigoz A, U...

Nat Med.

2012

Self-terminating diffraction gates femtosecond X-ray nanocrystallography measurements

Anton Barty, Carl Caleman, Andrew Aquila, Nicusor Timnean...

Nature Photonics 6, 35–40 (2012) doi:10.1038/nphoton.2011.297

2012

Recurrent mutation of the ID3 gene in Burkitt lymphoma identified by integrated genome, exome and transcriptome sequencing

Richter J, Schlesner M, Hoffmann S, Kreuz M, Leich E, Bur...

Nat Genet.

2012

Solid immersion facilitates fluorescence microscopy with nanometer resolution and sub-ångström emitter localization

Wildanger D, Patton BR, Schill H, Marseglia L, Hadden JP,...

Adv Mater. 2012 Nov 20;24(44):OP309-13. doi: 10.1002/adma.201203033

2012

Ultra-efficient ionization of heavy atoms by intense X-ray free-electron laser pulses

Benedikt Rudek, Sang-Kil Son, Lutz Foucar, Sascha W. Epp,...

Nature Photonics.

2012

A PP4 holoenzyme balances physiological and oncogenic nuclear factor-kappa B signaling in T lymphocytes

Brechmann M, Mock T, Nickles D, Kiessling M, Weit N, Breu...

Immunity. 2012 Oct 19;37(4):697-708. doi: 10.1016/j.immuni.2012.07.014

2012

Maturation-dependent HIV-1 surface protein redistribution revealed by fluorescence nanoscopy

Chojnacki J, Staudt T, Glass B, Bingen P, Engelhardt J, A...

Science. 2012 Oct 26;338(6106):524-8. doi: 10.1126/science.1226359

2012

Nanoscopy of living brain slices with low light levels

Testa I, Urban NT, Jakobs S, Eggeling C, Willig KI, Hell SW

Neuron. 2012 Sep 20;75(6):992-1000. doi: 10.1016/j.neuron.2012.07.028

2012

Active Wnt proteins are secreted on exosomes

Gross JC, Chaudhary V, Bartscherer K, Boutros M

Nat Cell Biol. 2012 Sep 16;14(10):1036-45. doi: 10.1038/ncb2574

2012

SAMHD1 restricts HIV-1 infection in resting CD4(+) T cells

Baldauf HM, Pan X, Erikson E, Schmidt S, Daddacha W, Burg...

Nat Med.

2012

Ubiquitin-Dependent Intramembrane Rhomboid Protease Promotes ERAD of Membrane Proteins

Fleig L, Bergbold N, Sahasrabudhe P, Geiger B, Kaltak L, ...

Mol Cell.

2012

Bergmann glial AMPA receptors are required for fine motor coordination

Saab AS, Neumeyer A, Jahn HM, Cupido A, Šimek AA, Boele H...

Science. 2012 Aug 10;337(6095):749-53. doi: 10.1126/science.1221140

2012

The first five seconds in the life of a clathrin-coated pit

Cocucci E, Aguet F, Boulant S, Kirchhausen T

Cell. 2012 Aug 3;150(3):495-507

2012

Viral immune modulators perturb the human molecular network by common and unique strategies

Pichlmair A, Kandasamy K, Alvisi G, Mulhern O, Sacco R, H...

Nature. 2012 Jul 26;487(7408):486-90

2012

High-resolution protein structure determination by serial femtosecond crystallography

Boutet S, Lomb L, Williams GJ, Barends TR, Aquila A, Doak...

Science. 2012 Jul 20;337(6092):362-4. doi: 10.1126/science.1217737

2012

Rescue of aging-associated decline in Dnmt3a2 expression restores cognitive abilities

Oliveira AM, Hemstedt TJ, Bading H

Nat Neurosci. 2012 Jul 1;15(8):1111-3. doi: 10.1038/nn.3151

2012

Fractal morphology, imaging and mass spectrometry of single aerosol particles in flight

Loh ND, Hampton CY, Martin AV, Starodub D, Sierra RG, Bar...

Nature. 2012 Jun 27;486(7404):513-7. doi: 10.1038/nature11222

2012

Tandem fluorescent protein timers for in vivo analysis of protein dynamics

Khmelinskii A, Keller PJ, Bartosik A, Meurer M, Barry JD,...

Nat Biotechnol.

2012

Synchronizing Nuclear Import of Ribosomal Proteins with Ribosome Assembly

Kressler D, Bange G, Ogawa Y, Stjepanovic G, Bradatsch B,...

Science.

2012

Calcium-channel number critically influences synaptic strength and plasticity at the active zone

Sheng J, He L, Zheng H, Xue L, Luo F, Shin W, Sun T, Kune...

Nat Neurosci. 2012 Jun 10;15(7):998-1006. doi: 10.1038/nn.3129

2012

Genome-wide RNAi screening identifies human proteins with a regulatory function in the early secretory pathway

Simpson JC, Joggerst B, Laketa V, Verissimo F, Cetin C, E...

Nat Cell Biol. 2012 Jun 3;14(7):764-74. doi: 10.1038/ncb2510

2012

Adolescent impulsivity phenotypes characterized by distinct brain networks

Whelan R, Conrod PJ, Poline JB, Lourdusamy A, Banaschewsk...

Nat Neurosci. 2012 Jun;15(6):920-5. doi: 10.1038/nn.3092

2012

Extracellular-matrix tethering regulates stem-cell fate

Trappmann B, Gautrot JE, Connelly JT, Strange DG, Li Y, O...

Nat Mater. 2012 May 27;11(7):642-9. doi: 10.1038/nmat3339

2012

The Structures of COPI-Coated Vesicles Reveal Alternate Coatomer Conformations and Interactions. Published online in Science Express

Faini M, Prinz S, Beck R, Schorb M, Riches JD, Bacia K, B...

Science.

2012

Long-range-projecting GABAergic neurons modulate inhibition in hippocampus and entorhinal cortex

Melzer S, Michael M, Caputi A, Eliava M, Fuchs EC, Whitti...

Science. 2012 Mar 23;335(6075):1506-10. doi: 10.1126/science.1217139

2012

Nanoscopy in a living mouse brain

Berning S, Willig KI, Steffens H, Dibaj P, Hell SW

Science. 2012 Feb 3;335(6068):551. doi: 10.1364/OE.20.005225

2012

On target: a public repository for large-scale RNAi experiments

Shamu CE, Wiemann S, Boutros M

Nat Cell Biol.

2012

In vivo protein crystallization opens new routes in structural biology

Koopmann R, Cupelli K, Redecke L, Nass K, Deponte DP, Whi...

Nat Methods. 2012 Jan 29;9(3):259-62. doi: 10.1038/nmeth.1859

2012

Lipidic phase membrane protein serial femtosecond crystallography

Johansson LC, Arnlund D, White TA, Katona G, Deponte DP, ...

Nat Methods. 2012 Jan 29;9(3):263-5. doi: 10.1038/nmeth.1867

2012

Molecular recognition of a single sphingolipid species by a protein's transmembrane domain

Contreras FX, Ernst AM, Haberkant P, Björkholm P, Lindahl...

Nature. 2012 Jan 9. doi: 10.1038/nature10742

2012

Diazepam binding inhibitor promotes progenitor proliferation in the postnatal SVZ by reducing GABA signaling

Alfonso J, Le Magueresse C, Zuccotti A, Khodosevich K, Mo...

Cell Stem Cell.

2011

RIM-binding protein, a central part of the active zone, is essential for neurotransmitter release

Liu KS, Siebert M, Mertel S, Knoche E, Wegener S, Wichman...

Science. 2011 Dec 16;334(6062):1565-9. doi: 10.1126/science.1212991

2011

A global circadian repressor controls antiphasic expression of metabolic genes in neurospora

Sancar G, Sancar C, Brügger B, Ha N, Sachsenheimer T, Gin...

Mol Cell. 2011 Dec 9;44(5):687-97. doi: 10.1016/j.molcel.2011.10.019

2011

Selective ribosome profiling reveals the cotranslational chaperone action of trigger factor in vivo

Oh E, Becker AH, Sandikci A, Huber D, Chaba R, Gloge F, N...

Cell. 2011 Dec 9;147(6):1295-308.

2011

Fate restriction and multipotency in retinal stem cells

Centanin L, Hoeckendorf B, Wittbrodt J.

Cell Stem Cell. 2011 Dec 2;9(6):553-62

2011

Hemoglobins S and C interfere with actin remodeling in Plasmodium falciparum-infected erythrocytes

Cyrklaff M, Sanchez CP, Kilian N, Bisseye C, Simpore J, F...

Science. 2011 Dec 2;334(6060):1283-6. Epub 2011 Nov 10.

2011

Control of Drosophila endocycles by E2F and CRL4(CDT2)

Zielke N, Kim KJ, Tran V, Shibutani ST, Bravo MJ, Nagaraj...

Nature. 2011 Oct 30;480(7375):123-7.

2011

Membrane protein sequestering by ionic protein-lipid interactions

van den Bogaart G, Meyenberg K, Risselada HJ, Amin H, Wil...

Nature. 2011 Oct 23;479(7374):552-5. doi: 10.1038/nature10545

2011

Diffraction-unlimited all-optical imaging and writing with a photochromic GFP

Grotjohann T, Testa I, Leutenegger M, Bock H, Urban NT, L...

Nature. 2011 Sep 11;478(7368):204-8. doi: 10.1038/nature10497

2011

A reversibly photoswitchable GFP-like protein with fluorescence excitation decoupled from switching

Brakemann T, Stiel AC, Weber G, Andresen M, Testa I, Grot...

Nat Biotechnol. 2011 Sep 11;29(10):942-7. doi: 10.1038/nbt.1952

2011

Circadian conformational change of the Neurospora clock protein FREQUENCY triggered by clustered hyperphosphorylation of a basic domain

Querfurth C, Diernfellner A, Gin E, Höfer T, Brunner M

Mol Cell. 2011 Sep 2;43(5):713-22. doi: 10.1016/j.molcel.2011.06.033

2011

In vivo expression profile of the antiviral restriction factor and tumor-targeting antigen CD317/BST-2/HM1.24/tetherin in humans

Erikson E, Adam T, Lehmann-Koch J, Schmidt S, Over B, Gof...

Proc Natl Acad Sci U S A. 2011 Aug 16;108(33):13688-93

2011

Actin dynamics counteract membrane tension during clathrin-mediated endocytosis

Boulant S, Kural C, Zeeh JC, Ubelmann F, Kirchhausen T.

Nat Cell Biol. 2011 Aug 14;13(9):1124-31. doi: 10.1038/ncb2307.

2011

Role of the clathrin terminal domain in regulating coated pit dynamics revealed by small molecule inhibition

von Kleist L, Stahlschmidt W, Bulut H, Gromova K, Puchkov...

Cell. 2011 Aug 5;146(3):471-84.

2011

Molecular mechanism of signal perception and integration by the innate immune sensor retinoic acid inducible gene-I (RIG-I).

Binder M, Eberle F, Seitz S, Mücke N, Hüber CM, Kiani N, ...

J Biol Chem. 2011 Aug 5;286(31):27278-87

2011

Structural Basis for Tail-Anchored Membrane Protein Biogenesis by the Get3-Receptor Complex

Stefer S, Reitz S, Wang F, Wild K, Pang YY, Schwarz D, Bo...

Science. 2011 Aug 5;333(6043):758-62

2011

Insight into structure and assembly of the nuclear pore complex by utilizing the genome of a eukaryotic thermophile

Amlacher S, Sarges P, Flemming D, van Noort V, Kunze R, D...

Cell 146(2):277-289. doi: 10.1016/j.cell.2011.06.039

2011

Thermodynamic stability of small hairpin RNAs highly influences the loading process of different mammalian Argonautes

Gu S, Jin L, Zhang F, Huang Y, Grimm D, Rossi JJ, Kay MA

Proc Natl Acad Sci U S A. 2011 May 31;108(22):9208-13. doi: 10.1073/pnas.1018023108

2011

Visualizing a Homogeneous Blend in Bulk Heterojunction Polymer Solar Cells by Analytical Electron Microscopy

Pfannmöller M, Flügge H, Benner G, Wacker I, Sommer C, Ha...

Nano Lett, July 19, 2011, DOI: 10.1021/nl201078t

2011

Nuclear Calcium-VEGFD Signaling Controls Maintenance of Dendrite Arborization Necessary for Memory Formation

Mauceri D, Freitag HE, Oliveira AM, Bengtson CP, Bading H

Neuron. 2011 Jul 14;71(1):117-30. doi: 10.1016/j.neuron.2011.04.022

2011

Sumoylation inhibits {alpha}-synuclein aggregation and toxicity

Krumova P, Meulmeester E, Garrido M, Tirard M, Hsiao HS, ...

J Cell Biol. 2011 Jul 11;194(1):49-60

2011

Perforin pores in the endosomal membrane trigger the release of endocytosed granzyme B into the cytosol of target cells

Thiery J, Keefe D, Boulant S, Boucrot E, Walch M, Martinv...

Nat Immunol. 2011 Jun 19;12(8):770-7. doi: 10.1038/ni.2050.

2011

PIAS-homologue Siz2 regulates perinuclear telomere position and telomerase activity in budding yeast

Ferreira HC, Luke B, Schober H, Kalck V, Lingner J, Gasse...

Nat Cell Biol. 2011 Jun 12. doi: 10.1038/ncb2263.

2011

A readily retrievable pool of synaptic vesicles

Hua Y, Sinha R, Thiel CS, Schmidt R, Hüve J, Martens H, H...

Nat Neurosci. 2011 Jun 12;14(7):833-9. doi: 10.1038/nn.2838

2011

Sharper low-power STED nanoscopy by time gating

Vicidomini G, Moneron G, Han KY, Westphal V, Ta H, Reuss ...

Nat Methods. 2011 Jun 5;8(7):571-3. doi: 10.1038/nmeth.1624

2011

HIV-1 Vpu Blocks Recycling and Biosynthetic Transport of the Intrinsic Immunity Factor CD317/Tetherin To Overcome the Virion Release Restriction

Schmidt S, Fritz JV, Bitzegeio J, Fackler OT, Keppler OT.

MBio. 2011 May 24;2(3).

2011

Viscoelastic response of contractile filament bundles

Besser A, Colombelli J, Stelzer EH, Schwarz US.

Phys Rev E Stat Nonlin Soft Matter Phys. 2011 May;83 (5 Pt 1):051902.

2011

Autoregulatory and repressive inputs localize Hydra Wnt3 to the head organizer

Nakamura Y, Tsiairis CT, Özbek S, Holstein TW

PNAS May 16, 2011, doi: 10.1073/pnas.1018109108

2011

Enterotypes of the human gut microbiome

Arumugam M, Raes J, Pelletier E, Le Paslier D, Yamada T, ...

Nature. 2011 May 12;473(7346):174-80. Epub 2011 Apr 20

2011

Combinations of protein-chemical complex structures reveal new targets for established drugs

Kalinina OV, Wichmann O, Apic G, Russell RB

PLoS Comput Biol. 2011 May;7(5):e1002043.

2011

Gap Junctions between Interneurons Are Required for Normal Spatial Coding in the Hippocampus and Short-Term Spatial Memory

Allen K, Fuchs EC, Jaschonek H, Bannerman DM, Monyer H.

J Neurosci. 2011 Apr 27;31(17):6542-52

2011

Live-cell visualization of dynamics of HIV budding site interactions with an ESCRT component

Baumgärtel V, Ivanchenko S, Dupont A, Sergeev M, Wiseman ...

Nat Cell Biol. 2011 Apr;13(4):469-74

2011

Mapping of signaling networks through synthetic genetic interaction analysis by RNAi

Horn T, Sandmann T, Fischer B, Axelsson E, Huber W, Boutr...

Nat Methods. 2011 Apr;8(4):341-6. Epub 2011 Mar 6.

2011

Thermal robustness of signaling in bacterial chemotaxis

Oleksiuk O, Jakovljevic V, Vladimirov N, Carvalho R, Past...

Cell. 2011 Apr 15;145(2):312-21.

2011

Directional switching of the kinesin Cin8 through motor coupling

Roostalu J, Hentrich C, Bieling P, Telley IA, Schiebel E,...

Science. 2011 Apr 1;332(6025):94-9.

2011

Minimum information about a marker gene sequence (MIMARKS) and minimum information about any (x) sequence (MIxS) specifications

Yilmaz P, Kottmann R, Field D, Knight R, Cole JR, Amaral-...

Nat. Biotechnol. 29(5):415-420. doi: 10.1038/nbt.1823

2011

Peripheral calcium-permeable AMPA receptors regulate chronic inflammatory pain in mice

Gangadharan V, Wang R, Ulzhöfer B, Luo C, Bardoni R, Bali...

J Clin Invest. 2011 Apr 1;121(4):1608-23

2011

Two-color nanoscopy of three-dimensional volumes by 4Pi detection of stochastically switched fluorophores

Aquino D, Schönle A, Geisler C, Middendorff CV, Wurm CA, ...

Nat Methods. 2011 Apr;8(4):353-9. doi: 10.1038/nmeth

2011

Far-field nanoscopy with reversible chemical reactions

Schwering M, Kiel A, Kurz A, Lymperopoulos K, Sprödefeld ...

Angew Chem Int Ed Engl. 2011 Mar 21;50(13):2940-5. doi: 10.1002/anie.201006013

2011

Micropilot: automation of fluorescence microscopy-based imaging for systems biology

Conrad C, Wünsche A, Tan TH, Bulkescher J, Sieckmann F, V...

Nat Methods. 2011 Mar;8(3):246-9.

2011

Wiring specificity in the direction-selectivity circuit of the retina

Briggman KL, Helmstaedter M, Denk W.

Nature. 2011 Mar 10;471(7337):183-8.

2011

The liver-specific microRNA miR-122 controls systemic iron homeostasis in mice

Castoldi M, Vujic Spasic M, Altamura S, Elmén J, Lindow M...

J Clin Invest. 2011 Apr 1;121(4):1386-96.

2011

Mechanics of Hsp70 chaperones enables differential interaction with client proteins

Schlecht R, Erbse AH, Bukau B, Mayer MP.

Nat Struct Mol Biol. 2011 Mar;18(3):345-51

2011

Visualizing a one-way protein encounter complex by ultrafast single-molecule mixing

Gambin Y, VanDelinder V, Ferreon AC, Lemke EA, Groisman A...

Nat Methods. 2011 Mar;8(3):239-41. doi: 10.1038/nmeth.1568

2011

The ecoresponsive genome of Daphnia pulex

Colbourne JK, Pfrender ME, Gilbert D, Thomas WK, Tucker A...

Science. 2011 Feb 4;331(6017):555-561. doi: 10.1126/science.1197761

2011

SecA interacts with ribosomes in order to facilitate posttranslational translocation in bacteria

Huber D, Rajagopalan N, Preissler S, Rocco MA, Merz F, Kr...

Mol Cell. 2011 Feb 4;41(3):343-53.

2011

Single mimivirus particles intercepted and imaged with an X-ray laser

Seibert MM, Ekeberg T, Maia FR, Svenda M, Andreasson J, J...

Nature. 2011 Feb 3;470(7332):78-81

2011

Femtosecond X-ray protein nanocrystallography

Chapman HN, Fromme P, Barty A, White TA, Kirian RA, Aquil...

Nature. 2011 Feb 3;470(7332):73-7

2011

Biochemical and morphological properties of hepatitis C virus particles and determination of their lipidome

Merz A, Long G, Hiet MS, Brügger B, Chlanda P, Andre P, W...

J Biol Chem. 2011 Jan 28;286(4):3018-32

2011

Recruitment and activation of a lipid kinase by hepatitis C virus NS5A is essential for integrity of the membranous replication compartment

Reiss S, Rebhan I, Backes P, Romero-Brey I, Erfle H, Matu...

Cell Host Microbe. 2011 Jan 20;9(1):32-45. doi: 10.1016/j.chom.2010.12.002

2011

EGFR/Ras/MAPK signaling mediates adult midgut epithelial homeostasis and regeneration in Drosophila

Jiang H, Grenley MO, Bravo MJ, Blumhagen RZ, Edgar BA.

Cell Stem Cell. 2011 Jan 7;8(1):84-95

2011

Protein localization in electron micrographs using fluorescence nanoscopy

Watanabe S, Punge A, Hollopeter G, Willig KI, Hobson RJ, ...

Nat Methods. 2011 Jan;8(1):80-4. doi: 10.1038/nmeth.1537

2010

The IMAGEN study: Reinforcement-related behaviour in normal brain function and psychopathology.

Schumann G, Loth E, Banaschewski T, Barbot A, Barker G, B...

Mol Psychiatry. 2010 Dec;15(12):1128-39.

2010

Components of the Hippo pathway cooperate with Nek2 kinase to regulate centrosome disjunction

Mardin BR, Lange C, Baxter JE, Hardy T, Scholz SR, Fry AM...

Nat Cell Biol. 2010 Dec;12(12):1166-76

2010

Large-scale in silico modeling of metabolic interactions between cell types in the human brain

Lewis NE, Schramm G, Bordbar A, Schellenberger J, Anderse...

Nat Biotechnol. 2010 Dec;28(12):1279-85

2010

Central mechanisms of pathological pain

Kuner R

Nat Med. 2010 Nov;16(11):1258-66

2010

Mutations in GRIN2A and GRIN2B encoding regulatory subunits of NMDA receptors cause variable neurodevelopmental phenotypes

Endele S, Rosenberger G, Geider K, Popp B, Tamer C, Stefa...

Nat Genet. 2010 Nov;42(11):1021-6

2010

The microRNA miR-182 is induced by IL-2 and promotes clonal expansion of activated helper T lymphocytes

Stittrich AB, Haftmann C, Sgouroudis E, Kühl AA, Hegazy A...

Nat Immunol. 2010 Nov;11(11):1057-62. doi: 10.1038/ni.1945

2010

Specific gene transfer to neurons, endothelial cells and hematopoietic progenitors with lentiviral vectors

Anliker B, Abel T, Kneissl S, Hlavaty J, Caputi A, Brynza...

Nat Methods. 2010 Nov;7(11):929-35.

2010

Serotonin receptor 1A-modulated phosphorylation of glycine receptor α3 controls breathing in mice

Manzke T, Niebert M, Koch UR, Caley A, Vogelgesang S, Hül...

J Clin Invest. 2010 Nov 1;120(11):4118-28. doi: 10.1172/JCI43029

2010

The cyclin E regulator cullin 3 prevents mouse hepatic progenitor cells from becoming tumor-initiating cells.

Kossatz U, Breuhahn K, Wolf B, Hardtke-Wolenski M, Wilken...

J Clin Invest. 2010 Nov 1;120(11):3820-33.

2010

Protein quality control in the cytosol and the endoplasmic reticulum: brothers in arms

Buchberger A, Bukau B, Sommer T.

Mol Cell. 2010 Oct 22;40(2):238-52.

2010

Mutations in the SHANK2 synaptic scaffolding gene in autism spectrum disorder and mental retardation

Berkel S, Marshall CR, Weiss B, Howe J, Roeth R, Moog U, ...

Nat Genet. 2010 Jun;42(6):489-91

2010

Far-field optical imaging and manipulation of individual spins with nanoscale resolution

Maurer PC, Maze JR, Stanwix PL, Jiang L, Gorshkov AV, Zib...

Nature Physics 6, 912–918, 2010. doi:10.1038/nphys1774

2010

Domain recombination: a workhorse for evolutionary innovation

Apic G, Russell RB

Sci Signal. 2010 Sep 14;3(139):pe30.

2010

Photoadaptation in Neurospora by competitive interaction of activating and inhibitory LOV domains

Malzahn E, Ciprianidis S, Káldi K, Schafmeier T, Brunner M

Cell. 2010 Sep 3;142(5):762-72

2010

Dissecting the molecular architecture of integrin adhesion sites by cryo-electron tomography

Patla I, Volberg T, Elad N, Hirschfeld-Warneken V, Grasho...

Nat Cell Biol. 2010 Sep;12(9):909-15

2010

CellCognition: time-resolved phenotype annotation in high-throughput live cell imaging

Held M, Schmitz MH, Fischer B, Walter T, Neumann B, Olma ...

Nat Methods. 2010 Sep;7(9):747-54

2010

Myeloid mineralocorticoid receptor controls macrophage polarization and cardiovascular hypertrophy and remodeling in mice

Usher MG, Duan SZ, Ivaschenko CY, Frieler RA, Berger S, S...

J Clin Invest. 2010 Sep 1;120(9):3350-64. doi: 10.1172/JCI41080

2010

Argonaute proteins are key determinants of RNAi efficacy, toxicity, and persistence in the adult mouse liver

Grimm D, Wang L, Lee JS, Schürmann N, Gu S, Börner K, Sto...

J Clin Invest. 2010 Sep;120(9):3106-19. doi: 10.1172/JCI43565

2010

The MicroArray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models

Shi L, Campbell G, Jones WD, Campagne F, Wen Z, Walker SJ...

Nat Biotechnol. 2010 Aug;28(8):827-38

2010

Fast, high-contrast imaging of animal development with scanned light sheet-based structured-illumination microscopy

Keller PJ, Schmidt AD, Santella A, Khairy K, Bao Z, Wittb...

Nat Methods. 2010 Aug;7(8):637-42.

2010

Wnt/Frizzled signaling requires dPRR, the Drosophila homolog of the prorenin receptor

Buechling T, Bartscherer K, Ohkawara B, Chaudhary V, Spir...

Curr Biol. 2010 Jul 27;20(14):1263-8

2010

Segregation of yeast nuclear pores

Khmelinskii A, Keller PJ, Lorenz H, Schiebel E, Knop M

Nature. 2010 Jul 22;466(7305):E1

2010

Two to tango: regulation of Mammalian iron metabolism

Hentze MW, Muckenthaler MU, Galy B, Camaschella C

Cell. 2010 Jul 9;142(1):24-38

2010

Nuclear transport receptor goes moonlighting

Gruss OJ

Nat Cell Biol. 2010 Jul;12(7):640-1

2010

Constitutively active Lck kinase in T cells drives antigen receptor signal transduction

Nika K, Soldani C, Salek M, Paster W, Gray A, Etzensperge...

Immunity. 2010 Jun 25;32(6):766-77. doi: 10.1016/j.immuni.2010.05.011

2010

Hormonal control of the shoot stem-cell niche

Zhao Z, Andersen SU, Ljung K, Dolezal K, Miotk A, Schulth...

Nature. 2010 Jun 24;465(7301):1089-92

2010

Prognostic impact of gene expression-based classification for neuroblastoma

Oberthuer A, Hero B, Berthold F, Juraeva D, Faldum A, Kah...

J Clin Oncol. 2010 Jul 20;28(21):3506-15

2010

The AAA-ATPase Rea1 drives removal of biogenesis factors during multiple stages of 60S ribosome assembly

Bassler J, Kallas M, Pertschy B, Ulbrich C, Thoms M, Hurt E

Mol Cell. 2010 Jun 11;38(5):712-21

2010

Immobilized chemokine fields and soluble chemokine gradients cooperatively shape migration patterns of dendritic cells

Schumann K, Lämmermann T, Bruckner M, Legler DF, Polleux ...

Immunity. 2010 May 28;32(5):703-13

2010

Structural basis for assembly and activation of the heterotetrameric SAGA histone H2B deubiquitinase module

Köhler A, Zimmerman E, Schneider M, Hurt E, Zheng N

Cell. 2010 May 14;141(4):606-17

2010

Characterizing light-regulated retinal microRNAs reveals rapid turnover as a common property of neuronal microRNAs

Krol J, Busskamp V, Markiewicz I, Stadler MB, Ribi S, Ric...

Cell. 2010 May 14;141(4):618-31

2010

In situ analysis of tyrosine phosphorylation networks by FLIM on cell arrays

Grecco HE, Roda-Navarro P, Girod A, Hou J, Frahm T, Truxi...

Nat Methods. 2010 Jun;7(6):467-72

2010

PP2A regulatory subunit PP2A-B' counteracts S6K phosphorylation

Hahn K, Miranda M, Francis VA, Vendrell J, Zorzano A, Tel...

Cell Metab. 2010 May 5;11(5):438-44.

2010

Activation of membrane-permeant caged PtdIns(3)P induces endosomal fusion in cells

Subramanian D, Laketa V, Müller R, Tischer C, Zarbakhsh S...

Nat Chem Biol. 2010 May;6(5):324-6

2010

CD317/tetherin is enriched in the HIV-1 envelope and downregulated from the plasma membrane upon virus infection

Habermann A, Krijnse-Locker J, Oberwinkler H, Eckhardt M,...

J Virol. 2010 May;84(9):4646-58

2010

Systematic analysis of human protein complexes identifies chromosome segregation proteins

Hutchins JR, Toyoda Y, Hegemann B, Poser I, Hériché JK, S...

Science. 2010 Apr 30;328(5978):593-9

2010

International network of cancer genome projects

International Cancer Genome Consortium

Nature. 2010 Apr 15;464(7291):993-8

2010

Gene regulation by nucleoporins and links to cancer

Köhler A, Hurt E

Mol Cell. 2010 Apr 9;38(1):6-15

2010

Variation in transcription factor binding among humans

Kasowski M, Grubert F, Heffelfinger C, Hariharan M, Asabe...

Science. 2010 Apr 9;328(5975):232-5

2010

A method and server for predicting damaging missense mutations

Adzhubei IA, Schmidt S, Peshkin L, Ramensky VE, Gerasimov...

Nat Methods. 2010 Apr;7(4):248-9

2010

Second messenger-mediated adjustment of bacterial swimming velocity

Boehm A, Kaiser M, Li H, Spangler C, Kasper CA, Ackermann...

Cell. 2010 Apr 2;141(1):107-16

2010

Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes

Neumann B, Walter T, Hériché JK, Bulkescher J, Erfle H, C...

Nature. 2010 Apr 1;464(7289):721-7. doi: 10.1038/nature08869

2010

miR390, Arabidopsis TAS3 tasiRNAs, and their AUXIN RESPONSE FACTOR targets define an autoregulatory network quantitatively regulating lateral root growth

Marin E, Jouannet V, Herz A, Lokerse AS, Weijers D, Vauch...

Plant Cell. 2010 Apr;22(4):1104-17

2010

A global map of human gene expression

Lukk M, Kapushesky M, Nikkilä J, Parkinson H, Goncalves A...

Nat Biotechnol. 2010 Apr;28(4):322-4

2010

Yeast pre-rRNA processing and modification occur cotranscriptionally

Kos M, Tollervey D.

Mol Cell. 2010 Mar 26;37(6):809-20

2010

The dynamic genome of Hydra

Chapman JA, Kirkness EF, Simakov O, Hampson SE, Mitros T,...

Nature. 2010 Mar 25;464(7288):592-6. doi: 10.1038/nature08830

2010

CKAMP44: a brain-specific protein attenuating short-term synaptic plasticity in the dentate gyrus

von Engelhardt J, Mack V, Sprengel R, Kavenstock N, Li KW...

Science. 2010 Mar 19;327(5972):1518-22

2010

Voltage control for B cell activation

Reth M, Dick TP.

Nat Immunol. 2010 Mar;11(3):265-72

2010

Visualization of image data from cells to organisms

Walter T, Shattuck DW, Baldock R, Bastin ME, Carpenter AE...

Nat Methods. 2010 Mar;7(3 Suppl):S26-41

2010

A human gut microbial gene catalogue established by metagenomic sequencing

Qin J, Li R, Raes J, Arumugam M, Burgdorf KS, Manichanh C...

Nature. 2010 Mar 4;464(7285):59-65

2010

Visualization of macromolecular structures

O'Donoghue SI, Goodsell DS, Frangakis AS, Jossinet F, Las...

Nat Methods. 2010 Mar;7(3 Suppl):S42-55

2010

Ancient animal microRNAs and the evolution of tissue identity

Christodoulou F, Raible F, Tomer R, Simakov O, Trachana K...

Nature. 2010 Feb 25;463(7284):1084-8

2010

Cell biology. When the beginning marks the end

Mogk A, Bukau B

Science. 2010 Feb 19;327(5968):966-7

2010

Synaptic inhibition in the olfactory bulb accelerates odor discrimination in mice

Abraham NM, Egger V, Shimshek DR, Renden R, Fukunaga I, S...

Neuron 2010 Feb 11;65(3): 399-411

2010

Genomic instability and myelodysplasia with monosomy 7 consequent to EVI1 activation after gene therapy for chronic granulomatous disease

Stein S, Ott MG, Schultze-Strasser S, Jauch A, Burwinkel ...

Nat Med. 2010 Feb;16(2):198-204

2010

Functional and evolutionary insights from the genomes of three parasitoid Nasonia species

Werren JH, Richards S, Desjardins CA, Niehuis O, Gadau J,...

Science. 2010 Jan 15;327(5963):343-8.. doi: 10.1126/science.1178028

2010

From experimental setup to bioinformatics: an RNAi screening platform to identify host factors involved in HIV-1 replication

Börner K, Hermle J, Sommer C, Brown NP, Knapp B, Glass B,...

Biotechnol J. 2010 Jan;5(1):39-49. doi: 10.1002/biot.200900226

2010

miR-200 de-FOGs insulin signaling

Teleman AA.

Cell Metab. 2010 Jan;11(1):8-9.

2010

Requirement of prorenin receptor and vacuolar H+-ATPase-mediated acidification for Wnt signaling

Cruciat CM, Ohkawara B, Acebron SP, Karaulanov E, Reinhar...

Science. 2010 Jan 22;327(5964):459-63.

2009

Adaptive force transmission in amoeboid cell migration

Renkawitz J, Schumann K, Weber M, Lämmermann T, Pflicke H...

Nat Cell Biol. 2009 Dec;11(12):1438-43

2009

Comprehensive genomic access to vector integration in clinical gene therapy.

Gabriel R, Eckenberg R, Paruzynski A, Bartholomae CC, Now...

Nat Med. 2009 Dec;15(12):1431-6.

2009

Proteome organization in a genome-reduced bacterium

Kühner S, van Noort V, Betts MJ, Leo-Macias A, Batisse C,...

Science. 2009 Nov 27;326(5957):1235-40.

2009

Hematopoietic stem cell gene therapy with a lentiviral vector in X-linked adrenoleukodystrophy.

Cartier N, Hacein-Bey-Abina S, Bartholomae CC, Veres G, S...

Science. 2009 Nov 6;326(5954):818-23.

2009

Evolution of biomolecular networks: lessons from metabolic and protein interactions

Yamada T, Bork P

Nat Rev Mol Cell Biol. 2009 Nov;10(11):791-803

2009

Cooperative binding of two acetylation marks on a histone tail by a single bromodomain

Morinière J, Rousseaux S, Steuerwald U, Soler-López M, Cu...

Nature. 2009 Oct 1;461(7264):664-8.

2009

p53 deletion impairs clearance of chromosomal-instable stem cells in aging telomere-dysfunctional mice.

Begus-Nahrmann Y, Lechel A, Obenauf AC, Nalapareddy K, Pe...

Nat Genet. 2009 Oct;41(10):1138-43.

2009

Trigger factors find new jobs and contacts.

Hoffmann A, Bukau B.

Nat Struct Mol Biol. 2009 Oct;16(10):1006-8.

2009

Phosphorylation modulates rapid nucleocytoplasmic shuttling and cytoplasmic accumulation of Neurospora clock protein FRQ on a circadian time scale

Diernfellner AC, Querfurth C, Salazar C, Höfer T, Brunner M

Genes Dev. 2009 Sep 15;23(18):2192-200. doi: 10.1101/gad.538209

2009

Mechanochemical Removal of Ribosome Biogenesis Factors from Nascent 60S Ribosomal Subunits

Ulbrich C, Diepholz M, Bassler J, Kressler D, Pertschy B,...

Cell. 2009 Sep 4;138(5):911-22

2009

A genetically encoded photoactivatable Rac controls the motility of living cells.

Wu YI, Frey D, Lungu OI, Jaehrig A, Schlichting I, Kuhlma...

Nature. 2009 Sep 3;461(7260):104-8

2009

Chromatin shapes the mitotic spindle.

Dinarina A, Pugieux C, Corral MM, Loose M, Spatz J, Karse...

Cell. 2009 Aug 7;138(3):426-8.

2009

The death receptor CD95 activates adult neural stem cells for working memory formation and brain repair.

Corsini NS, Sancho-Martinez I, Laudenklos S, Glagow D, Ku...

Cell Stem Cell. 2009 Aug 7;5(2):178-90.

2009

Mutations affecting the secretory COPII coat component SEC23B cause congenital dyserythropoietic anemia type II.

Schwarz K, Iolascon A, Verissimo F, Trede NS, Horsley W, ...

Nat Genet. 2009 Aug;41(8):936-40.

2009

Hematopoietic colony-stimulating factors mediate tumor-nerve interactions and bone cancer pain

Schweizerhof M, Stösser S, Kurejova M, Njoo C, Gangadhara...

Nat. Med. 2009 Jul;15(7):802-7

2009

Identification of cholesterol-regulating genes by targeted RNAi screening

Bartz F, Kern L, Erz D, Zhu M, Gilbert D, Meinhof T, Wirk...

Cell Metab. 2009 Jul;10(1):63-75. doi: 10.1016/j.cmet.2009.05.009

2009

The SESA network links duplication of the yeast centrosome with the protein translation machinery.

Sezen B, Seedorf M, Schiebel E.

Genes Dev. 2009 Jul 1;23(13):1559-70.

2009

Diffraction-unlimited three-dimensional optical nanoscopy with opposing lenses

Hell SW, Schmidt R, Egner A

Nat Photonics. Jul 2009. Vol 3, 381 - 387. doi:10.1038/nphoton.2009.112

2009

Cytokine/Jak/Stat signaling mediates regeneration and homeostasis in the Drosophila midgut

Jiang H, Patel PH, Kohlmaier A, Grenley MO, McEwen DG, Ed...

Cell. 2009 Jun 26;137(7):1343-55.

2009

Structure and mechanism of a bacterial light-regulated cyclic nucleotide phosphodiesterase.

Barends TR, Hartmann E, Griese JJ, Beitlich T, Kirienko N...

Nature. 2009 Jun 18;459(7249):1015-8.

2009

A functional screen implicates microRNA-138-dependent regulation of the depalmitoylation enzyme APT1 in dendritic spine morphogenesis.

Siegel G, Obernosterer G, Fiore R, Oehmen M, Bicker S, Ch...

Nat Cell Biol. 2009 Jun;11(6):705-16.

2009

Microscopy and its focal switch

Hell SW

Nat Methods. 2009 Jan;6(1):24-32. doi: 10.1038/nmeth.1291

2009

Sequential polarization and imprinting of T-helper type 1 differentiation by interferon-? and interleukin-12.

Schulz EG, Mariani L, Radbruch A, Höfer T.

Immunity. 2009 May;30(5):673-83

2009

SCAI acts as a suppressor of cancer cell invasion through the transcriptional control of beta1-integrin.

Brandt DT, Baarlink C, Kitzing TM, Kremmer E, Ivaska J, N...

Nat Cell Biol. 2009 May;11(5):540-2.

2009

Cell biology: Arrest by ribosome.

Ferreira-Cerca S, Hurt E.

Nature. 2009 May 7;459(7243):46-7.

2009

Delivering proteins for export from the cytosol

Cross BC, Sinning I, Luirink J, High S

Nat Rev Mol Cell Biol. 2009 Apr;10(4):255-64

2009

The genotoxic potential of retroviral vectors is strongly modulated by vector design and integration site selection in a mouse model of HSC gene therapy.

Montini E, Cesana D, Schmidt M, Sanvito F, Bartholomae CC...

J Clin Invest. 2009 Apr;119(4):964-75.

2009

Tuning of synapse number, structure and function in the cochlea

Meyer AC, Frank T, Khimich D, Hoch G, Riedel D, Chapochni...

Nat Neurosci. 2009 Apr;12(4):444-53. doi: 10.1038/nn.2293

2009

Sus1, Cdc31 and the Sac3 CID region form a conserved interaction platform that promotes nuclear pore association and mRNA export.

Jani D, Lutz S, Marshall NJ, Fischer T, Köhler A, Ellisdo...

Mol Cell. 2009 Mar 27;33(6):727-37.

2009

HIV-1 antagonism of CD317 is species specific and involves Vpu-mediated proteasomal degradation of the restriction factor.

Goffinet C, Allespach I, Homann S, Tervo HM, Habermann A,...

Cell Host Microbe. 2009 Mar 19;5(3):285-97.

2009

Signal sequences get active

Sinning I, Wild K, Bange G

Nat Chem Biol. 2009 Mar;5(3):146-7

2009

Electrochemical cues regulate assembly of the Frizzled/Dishevelled complex at the plasma membrane during planar epithelial polarization.

Simons M, Gault WJ, Gotthardt D, Rohatgi R, Klein TJ, Sha...

Nat Cell Biol. 2009 Mar;11(3):286-94.

2009

Direct observation of the nanoscale dynamics of membrane lipids in a living cell

Eggeling C, Ringemann C, Medda R, Schwarzmann G, Sandhoff...

Nature. 2009 Feb 26;457(7233):1159-62. doi: 10.1038/nature07596

2009

Bidirectional promoters generate pervasive transcription in yeast

Xu Z, Wei W, Gagneur J, Perocchi F, Clauder-Münster S, Ca...

Nature. 2009 Feb 19;457(7232):1033-7

2009

RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins.

Doil C, Mailand N, Bekker-Jensen S, Menard P, Larsen DH, ...

Cell. 2009 Feb 6;136(3):435-46.

2009

Mechanisms of regulated unconventional protein secretion.

Nickel W, Rabouille C.

Nat Rev Mol Cell Biol. 2009 Feb;10(2):148-55.

2009

Loss of viral fitness and cross-recognition by CD8+ T cells limit HCV escape from a protective HLA-B27-restricted human immune response.

Dazert E, Neumann-Haefelin C, Bressanelli S, Fitzmaurice ...

J Clin Invest. 2009 Feb;119(2):376-86. doi: 10.1172/JCI36587

2009

Microscopy: Light from the dark

Hell SW, Rittweger E

Nature. 2009 Oct 22;461(7267):1069-70. doi: 10.1038/4611069a

2009

Genetically-encoded photoactivatable Rac analogs reveal spatio-temporal coordination of Rac and Rho during cell motility

Wu YI, Frey D, Lungu O, Jaehrig A, Schlichting I, Kuhlman...

2009 Nature 461:104-108

2009

Nexilin mutations destabilize cardiac Z-disks and lead to dilated cardiomyopathy

Hassel D, Dahme T, Erdmann J, Meder B, Huge A, Stoll M, J...

Nat Med. 2009 Nov;15(11):1281-8.

2009

STED microscopy reveals crystal colour centres with nanometric resolution

Rittweger E, Han KY, Irvine SE, Eggeling C, Hell SW

Nature Photonics, 3(3), 144-147. doi: 10.1038/NPHOTON.2009.2

2008

MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts.

Thum T, Gross C, Fiedler J, Fischer T, Kissler S, Bussen ...

Nature. 2008 Dec 18;456(7224):980-4.

2008

Circadian activity and abundance rhythms of the Neurospora clock transcription factor WCC associated with rapid nucleo-cytoplasmic shuttling.

Schafmeier T, Diernfellner A, Schäfer A, Dintsis O, Neiss...

Genes Dev. 2008 Dec 15;22(24):3397-402.

2008

An oncogenomics-based in vivo RNAi screen identifies tumor suppressors in liver cancer

Zender L, Xue W, Zuber J, Semighini CP, Krasnitz A, Ma B,...

Cell. 2008 Nov 28;135(5):852-64

2008

Targeting and tinkering with interaction networks

Russell RB, Aloy P.

Nat Chem Biol. 2008 Nov;4(11):666-73

2008

Regulation of microtubule dynamics by reaction cascades around chromosomes.

Athale CA, Dinarina A, Mora-Coral M, Pugieux C, Nedelec F...

Science. 2008 Nov 21;322(5905):1243-7

2008

Mechanism of phototaxis in marine zooplankton.

Jékely G, Colombelli J, Hausen H, Guy K, Stelzer E, Nédél...

Nature. 2008 Nov 20;456(7220):395-9.

2008

Reconstruction of zebrafish early embryonic development by scanned light sheet microscopy.

Keller PJ, Schmidt AD, Wittbrodt J, Stelzer EH.

Science. 2008 Nov 14;322(5904):1065-9.

2008

Molecular basis for regulation of the heat shock transcription factor sigma32 by the DnaK and DnaJ chaperones.

Rodriguez F, Arsène-Ploetze F, Rist W, Rüdiger S, Schneid...

Mol Cell. 2008 Nov 7;32(3):347-58.

2008

Fluorescence nanoscopy by ground-state depletion and single-molecule return

Fölling J, Bossi M, Bock H, Medda R, Wurm CA, Hein B, Jak...

Nat Methods. 2008 Nov;5(11):943-5. doi: 10.1038/nmeth.1257

2008

Biochemistry. Not comparable, but complementary.

Jensen LJ, Bork P.

Science. 2008 Oct 3;322(5898):56-7.

2008

Regulation of muscle development by DPF3, a novel histone acetylation and methylation reader of the BAF chromatin remodeling complex.

Lange M, Kaynak B, Forster UB, Tönjes M, Fischer JJ, Grim...

Genes Dev. 2008 Sep 1;22(17):2370-84.

2008

Photoswitchable fluorescent proteins enable monochromatic multilabel imaging and dual color fluorescence nanoscopy

Andresen M, Stiel AC, Fölling J, Wenzel D, Schönle A, Egn...

Nat Biotechnol. 2008 Sep;26(9):1035-40. doi: 10.1038/nbt.1493

2008

The contribution of single synapses to sensory representation in vivo

Arenz A, Silver RA, Schaefer AT, Margrie TW

Science. 2008 Aug 15;321(5891):977-80

2008

High-resolution mapping of meiotic crossovers and non-crossovers in yeast

Mancera E, Bourgon R, Brozzi A, Huber W, Steinmetz LM.

Nature. 2008 Jul 24;454(7203):479-85

2008

Structural basis for specific substrate recognition by the chloroplast signal recognition particle protein cpSRP43

Stengel KF, Holdermann I, Cain P, Robinson C, Wild K, Sin...

Science. 2008 Jul 11;321(5886):253-6

2008

Drug target identification using side-effect similarity.

Campillos M, Kuhn M, Gavin AC, Jensen LJ, Bork P.

Science. 2008 Jul 11;321(5886):263-6.

2008

Fine tuning of hepcidin expression by positive and negative regulators

Muckenthaler MU.

Cell Metab. 2008 Jul;8(1):1-3.

2008

Molecular eco-systems biology: towards an understanding of community function

Raes J, Bork P

Nat. Rev. Microbiol. 6(9):693-699. doi: 10.1038/nrmicro1935

2008

Mechanism and consequences for paralog-specific sumoylation of ubiquitin-specific protease 25.

Meulmeester E, Kunze M, Hsiao HH, Urlaub H, Melchior F.

Mol Cell. 2008 Jun 6;30(5):610-9.

2008

Lego clocks: building a clock from parts.

Brunner M, Simons MJ, Merrow M.

Genes Dev. 2008 Jun 1;22(11):1422-6.

2008

Spherical nanosized focal spot unravels the interior of cells

Schmidt R, Wurm CA, Jakobs S, Engelhardt J, Egner A, Hell SW

Nat Methods. 2008 Jun;5(6):539-44. doi: 10.1038/nmeth.1214

2008

Evolution of metal hyperaccumulation required cis-regulatory changes and copy number expansion of HMA4.

Hanikenne M, Talke IN, Haydon MJ, Lanz C, Nolte A, Motte ...

Nature. 2008 May 15;453(7193):391-5.

2008

The genome of the model beetle and pest Tribolium castaneum

Tribolium Genome Sequencing Consortium

Nature. 2008 Apr 24;452(7190):949-55

2008

Reduced V-ATPase activity in the trans-Golgi network causes oxylipin-dependent hypocotyl growth Inhibition in Arabidopsis

Brüx A, Liu TY, Krebs M, Stierhof YD, Lohmann JU, Miersch...

Plant Cell. 2008 Apr;20(4):1088-100.

2008

Cell biology: SUMO.

Meulmeester E, Melchior F.

Nature. 2008 Apr 10;452(7188):709-11.

2008

The green yeast uses its plant-like clock to regulate its animal-like tail.

Brunner M, Merrow M

Genes Dev. 2008 Apr 1;22(7):825-31.

2008

Control of visually guided behavior by distinct populations of spinal projection neurons.

Orger MB, Kampff AR, Severi KE, Bollmann JH, Engert F.

Nat Neurosci. 2008 Mar;11(3):327-33.

2008

A peptide deformylase-ribosome complex reveals mechanism of nascent chain processing.

Bingel-Erlenmeyer R, Kohler R, Kramer G, Sandikci A, Anto...

Nature. 2008 Mar 6;452(7183):108-11.

2008

Ceramide triggers budding of exosome vesicles into multivesicular endosomes.

Trajkovic K, Hsu C, Chiantia S, Rajendran L, Wenzel D, Wi...

Science. 2008 Feb 29;319(5867):1244-7.

2008

The genome of the choanoflagellate Monosiga brevicollis and the origin of metazoans

King N, Westbrook MJ, Young SL, Kuo A, Abedin M, Chapman ...

Nature. 2008 Feb 14;451(7180):783-788. doi: 10.1038/nature06617

2008

Hfe acts in hepatocytes to prevent hemochromatosis

Vujić Spasić M, Kiss J, Herrmann T, Galy B, Martinache S,...

Cell Metab. 2008 Feb;7(2):173-8.

2008

Long-lived virus-reactive memory T cells generated from purified cytokine-secreting T helper type 1 and type 2 effectors

Löhning M, Hegazy AN, Pinschewer DD, Busse D, Lang KS, Hö...

J Exp Med. 2008 Jan 21;205(1):53-61. doi: 10.1084/jem.20071855

2008

Structural basis of the nic96 subcomplex organization in the nuclear pore channel

Schrader N, Stelter P, Flemming D, Kunze R, Hurt E, Vette...

Mol Cell. 2008 Jan 18;29(1):46-55.

2008

Nutritional control of protein biosynthetic capacity by insulin via Myc in Drosophila

Teleman AA, Hietakangas V, Sayadian AC, Cohen SM.

Cell Metab. 2008 Jan;7(1):21-32

2008

Unconventional mechanisms of protein transport to the cell surface of eukaryotic cells.

Nickel W, Seedorf M.

Annu Rev Cell Dev Biol. 2008;24:287-308.

2007

Semen-derived amyloid fibrils drastically enhance HIV Infection.

Münch J, Rücker E, Ständker L, Adermann K, Goffinet C, Sc...

Cell. 2007 Dec 14;131(6):1059-71.

2007

Control of protein phosphorylation with a genetically encoded photocaged amino acid

Lemke EA, Summerer D, Geierstanger BH, Brittain SM, Schul...

Nat Chem Biol. 2007 Dec;3(12):769-72

2007

Therapeutic application of RNAi: is mRNA targeting finally ready for prime time?

Grimm D, Kay MA

J Clin Invest. 2007 Dec;117(12):3633-41

2007

Competition for cytokines: T(reg) cells take all

Scheffold A, Murphy KM, Höfer T

Nat Immunol. 2007 Dec;8(12):1285-7. doi: 10.1038/ni1207-1285

2007

Rapid control of protein level in the apicomplexan Toxoplasma gondii.

Herm-Götz A, Agop-Nersesian C, Münter S, Grimley JS, Wand...

Nat Methods. 2007 Dec;4(12):1003-5.

2007

Concepts in SUMOylation: a decade on.

Geiss-Friedlander R, Melchior F.

Nat Rev Mol Cell Biol. 2007 Dec;8(12):947-56.

2007

Genome-wide experimental determination of barriers to horizontal gene transfer

Sorek R, Zhu Y, Creevey CJ, Francino MP, Bork P, Rubin EM

Science 318(5855):1449-1452. doi: 10.1126/science.1147112

2007

Lipid droplets highjack SNAREs

Söllner TH.

Nat Cell Biol. 2007 Nov;9(11):1219-20

2007

Exporting RNA from the nucleus to the cytoplasm

Köhler A, Hurt E.

Nat Rev Mol Cell Biol. 2007 Oct;8(10):761-73.

2007

Exonuclease-1 deletion impairs DNA damage signaling and prolongs lifespan of telomere-dysfunctional mice

Schaetzlein S, Kodandaramireddy NR, Ju Z, Lechel A, Stepc...

Cell. 2007 Sep 7;130(5):863-77

2007

Arx1 functions as alternative nuclear export receptor for the 60S pre-ribosomal subunit

Bradatsch B, Katahira J, Kowalinsk Ei, Bange G, Yao W, Se...

Mol Cell. 2007 Sep 7;27(5):767-79.

2007

The lipid droplet is an important organelle for hepatitis C virus production.

Miyanari Y, Atsuzawa K, Usuda N, Watashi K, Hishiki T, Za...

Nat Cell Biol. 2007 Sep;9(9):1089-97.

2007

Redox regulation of peptide receptivity of major histocompatibility complex class I molecules by ERp57 and tapasi

Kienast A, Preuss M, Winkler M, Dick TP.

Nat Immunol. 2007 Aug;8(8):864-72

2007

Self-organization of MTOCs replaces centrosome function during acentrosomal spindle assembly in live mouse oocytes.

Schuh M, Ellenberg J.

Cell. 2007 Aug 10;130(3):484-98.

2007

Vector integration is nonrandom and clustered and influences the fate of lymphopoiesis in SCID-X1 gene therapy.

Deichmann A, Hacein-Bey-Abina S, Schmidt M, Garrigue A, B...

J Clin Invest. 2007 Aug;117(8):2225-32.

2007

Maximal chromosome compaction occurs by axial shortening in anaphase and depends on Aurora kinase.

Mora-Bermúdez F, Gerlich D, Ellenberg J.

Nat Cell Biol. 2007 Jul;9(7):822-31

2007

Molecular basis for the functional interaction of dynein light chain with the nuclear pore complex

Stelter P, Kunze R, Flemming D, Höpfner D, Diepholz M, Ph...

Nat Cell Biol. 2007 Jul;9(7):788-96.

2007

Trawler: de novo regulatory motif discovery pipeline for chromatin immunoprecipitation

Ettwiller L, Paten B, Ramialison M, Birney E, Wittbrodt J

Nat Methods. 2007 Jul;4(7):563-5

2007

Systematic discovery of in vivo phosphorylation networks

Linding R, Jensen LJ, Ostheimer GJ, van Vugt MA, Jørgense...

Cell. 2007 Jun 29;129(7):1415-1426. doi: 10.1016/j.cell.2007.05.052

2007

Wnt induces LRP6 signalosomes and promotes dishevelled-dependent LRP6 phosphorylation.

Bilic J, Huang YL, Davidson G, Zimmermann T, Cruciat CM, ...

Science. 2007 Jun 15;316(5831):1619-22.

2007

Nuclear export of ribosomal 60S subunits by the general mRNA export receptor Mex67-Mtr2

Yao W, Roser D, Köhler A, Bradatsch B, Bassler J, Hurt E

Mol Cell. 2007 Apr 13;26(1):51-62

2007

Ca2+ channel blockers reverse iron overload by a new mechanism via divalent metal transporter-1.

Ludwiczek S, Theurl I, Muckenthaler MU, Jakab M, Mair SM,...

Nat Med. 2007 Apr;13(4):448-54.

2007

Modulation of the immunological synapse: a key to HIV-1 pathogenesis?

Fackler OT, Alcover A, Schwartz O.

Nat Rev Immunol. 2007 Apr;7(4):310-7.

2007

Quantitative phylogenetic assessment of microbial communities in diverse environments.

von Mering C, Hugenholtz P, Raes J, Tringe SG, Doerks T, ...

Science 315(5815):1126-1130. doi: 10.1126/science.1133420

2007

Gadd45a promotes epigenetic gene activation by repair-mediated DNA demethylation.

Barreto G, Schäfer A, Marhold J, Stach D, Swaminathan SK,...

Nature. 2007 Feb 8;445(7128):671-5.

2007

M-domains couple the ClpB threading motor with the DnaK chaperone activity

Haslberger T, Weibezahn J, Zahn R, Lee S, Tsai FT, Bukau ...

Mol Cell. 2007 Jan 26;25(2):247-60.

2007

Cdkn1a deletion improves stem cell function and lifespan of mice with dysfunctional telomeres without accelerating cancer formation.

Choudhury AR, Ju Z, Djojosubroto MW, Schienke A, Lechel A...

Nat Genet. 2007 Jan;39(1):99-105.

2007

Direct monitoring of formation and dissociation of individual metal complexes by single-molecule fluorescence spectroscopy

Kiel A, Kovacs J, Mokhir A, Krämer R, Herten DP

Angew Chem Int Ed Engl. 2007 Apr 27;46(18):3363-3366. doi: 10.1002/anie.200604965

2006

Following the signal sequence from ribosomal tunnel exit to signal recognition particle

Halic M, Blau M, Becker T, Mielke T, Pool MR, Wild K, Sin...

Nature. 2006 Nov 23;444(7118):507-11

2006

Individual cell migration serves as the driving force for optic vesicle evagination.

Rembold M, Loosli F, Adams RJ, Wittbrodt J.

"Science. 2006 Aug 25;313(5790):1130-4."

2006

High-throughput RNAi screening by time-lapse imaging of live human cells

Neumann B, Held M, Liebel U, Erfle H, Rogers P, Pepperkok...

Nat Methods. 2006 May;3(5):385-90

2006

Vaccinia virus-induced cell motility requires F11L-mediated inhibition of RhoA signaling

Valderrama F, Cordeiro JV, Schleich S, Frischknecht F, Way M

Science. 2006 Jan 20;311(5759):377-81

2005

IKK mediates ischemia-induced neuronal death

Herrmann O, Baumann B, de Lorenzi R, Muhammad S, Zhang W,...

Nat Med. 2005 Dec;11(12):1322-9.

2000

A complex of N-WASP and WIP integrates signalling cascades that lead to actin polymerization

Moreau V, Frischknecht F, Reckmann I, Vincentelli R, Rabu...

Nat Cell Biol. 2000 Jul;2(7):441-8

1999

Actin-based motility of vaccinia virus mimics receptor tyrosine kinase signalling

Frischknecht F, Moreau V, Röttger S, Gonfloni S, Reckmann...

Nature. 1999 Oct 28;401(6756):926-9

Meta Navigation

Main Navigation

Breadcrumb Navigation

Area Navigation