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2017
DNMT and HDAC inhibitors induce cryptic transcription start sites encoded in long terminal repeats
Brocks D, Schmidt CR, Daskalakis M, Jang HS, Shah NM, Li ...
Nat Genet. 2017 Jul;49(7):1052-1060. doi: 10.1038/ng.3889
2017
Broad-spectrum agents for flaviviral infections: dengue, Zika and beyond
Boldescu V, Behnam MAM, Vasilakis N, Klein CD
Nat Rev Drug Discov. 2017 May 5. doi: 10.1038/nrd.2017.33
2017
Progress in imaging methods: insights gained into Plasmodium biology
De Niz M, Burda PC, Kaiser G, Del Portillo HA, Spielmann ...
Nat Rev Microbiol. 2017 Jan;15(1):37-54. doi: 10.1038/nrmicro.2016.158
2016
The structure and flexibility of conical HIV-1 capsids determined within intact virions
Mattei S, Glass B, Hagen WJ, Kräusslich HG, Briggs JA
Science. 2016 Dec 16;354(6318):1434-1437.
2016
Transcriptional programs that control expression of the autoimmune regulator gene Aire
Herzig Y, Nevo S, Bornstein C, Brezis MR, Ben-Hur S, Shke...
Nat Immunol. 2016 Dec 12. doi: 10.1038/ni.3638
2016
Nuclear landscape of HIV-1 infection and integration
Lusic M, Siliciano RF
Nat Rev Microbiol. 2016 Dec 12. doi: 10.1038/nrmicro.2016.162
2016
Alternative modes of client binding enable functional plasticity of Hsp70
Mashaghi A, Bezrukavnikov S, Minde DP, Wentink AS, Kityk ...
Nature. 2016 Nov 17;539(7629):448-451. doi: 10.1038/nature20137
2016
Transient RNA-DNA Hybrids Are Required for Efficient Double-Strand Break Repair
Ohle C, Tesorero R, Schermann G, Dobrev N, Sinning I, Fis...
Cell. 2016 Nov 3;167(4):1001-1013.e7. doi: 10.1016/j.cell.2016.10.001
2016
Vascular endothelial growth factor: a neurovascular target in neurological diseases
Lange C, Storkebaum E, de Almodóvar CR, Dewerchin M, Carm...
Nat Rev Neurol. 2016 Aug;12(8):439-54. doi: 10.1038/nrneurol.2016.88
2016
Global profiling of SRP interaction with nascent polypeptides
Schibich D, Gloge F, Pöhner I, Björkholm P, Wade RC, von ...
Nature. 2016 Aug 11;536(7615):219-23
2016
Tumour-cell-induced endothelial cell necroptosis via death receptor 6 promotes metastasis
Strilic B, Yang L, Albarrán-Juárez J, Wachsmuth L, Han K,...
Nature. 2016 Aug 11;536(7615):215-8
2016
Crystal structure of Zika virus NS2B-NS3 protease in complex with a boronate inhibitor
Lei J, Hansen G, Nitsche C, Klein CD, Zhang L, Hilgenfeld R
Science. 2016 Jul 29;353(6298):503-5. doi: 10.1126/science.aag2419
2016
Pre-assembled Nuclear Pores Insert into the Nuclear Envelope during Early Development
Hampoelz B, Mackmull MT, Machado P, Ronchi P, Bui KH, Sch...
Cell. 2016 Jul 28;166(3):664-78. doi: 10.1016/j.cell.2016.06.015
2016
Molecular biology: A surprise beginning for RNA
Höfer K, Jäschke A
Nature. 2016 Jul 21;535(7612):359-60
2016
An atomic model of HIV-1 capsid-SP1 reveals structures regulating assembly and maturation
Schur FK, Obr M, Hagen WJ, Wan W, Jakobi AJ, Kirkpatrick ...
Science. 2016 Jul 14. pii: aaf9620
2016
Architecture of the 90S Pre-ribosome: A Structural View on the Birth of the Eukaryotic Ribosome
Kornprobst M, Turk M, Kellner N, Cheng J, Flemming D, Koš...
Cell. 2016 Jul 14;166(2):380-93. doi: 10.1016/j.cell.2016.06.014
2016
Data-driven hypothesis weighting increases detection power in genome-scale multiple testing
Ignatiadis N, Klaus B, Zaugg JB, Huber W
Nat Methods. 2016 Jul;13(7):577-80. doi: 10.1038/nmeth.3885
2016
Spatially segregated feedforward and feedback neurons support differential odor processing in the lateral entorhinal cortex
Leitner FC, Melzer S, Lütcke H, Pinna R, Seeburg PH, Helm...
Nat Neurosci. 2016 Jul;19(7):935-44. doi: 10.1038/nn.4303
2016
Automated structure modeling of large protein assemblies using crosslinks as distance restraints
Ferber M, Kosinski J, Ori A, Rashid UJ, Moreno-Morcillo M...
Nat Methods. 2016 Jun;13(6):515-20. doi: 10.1038/nmeth.3838
2016
Automated structure modeling of large protein assemblies using crosslinks as distance restraints
Ferber M, Kosinski J, Ori A, Rashid UJ, Moreno-Morcillo M...
Nat Methods. 2016 Jun;13(6):515-20. doi: 10.1038/nmeth.3838
2016
Molecular architecture of the inner ring scaffold of the human nuclear pore complex
Kosinski J, Mosalaganti S, von Appen A, Teimer R, DiGuili...
Science. 2016 Apr 15;352(6283):363-5. doi: 10.1126/science.aaf0643
2016
Molecular architecture of the inner ring scaffold of the human nuclear pore complex
Kosinski J, Mosalaganti S, von Appen A, Teimer R, DiGuili...
Science. 2016 Apr 15;352(6283):363-5. doi: 10.1126/science.aaf0643
2016
A new population of parvocellular oxytocin neurons controlling magnocellular neuron activity and inflammatory pain processing
Eliava M, Melchior M, Knobloch-Bollmann HS, Wahis J, da S...
NEURON 2016 Mar 16;89(6):1291-1304. doi: 10.1016/j.neuron.2016.01.041.
2016
SuReSim: simulating localization microscopy experiments from ground truth models
Venkataramani V, Herrmannsdörfer F, Heilemann M, Kuner T.
Nat Methods. 2016 Apr;13(4):319-21. doi: 10.1038/nmeth.3775. Epub 2016 Feb 29.
2016
Complex Interdependence Regulates Heterotypic Transcription Factor Distribution and Coordinates Cardiogenesis
Luna-Zurita L, Stirnimann CU, Glatt S, Kaynak BL, Thomas ...
Cell. 2016 Feb 25;164(5):999-1014. doi: 10.1016/j.cell.2016.01.004
2016
Myc Depletion Induces a Pluripotent Dormant State Mimicking Diapause
Scognamiglio R, Cabezas-Wallscheid N, Thier MC, Altamura ...
Cell. 2016 Feb 11;164(4):668-80. doi: 10.1016/j.cell.2015.12.033
2016
Plankton networks driving carbon export in the oligotrophic ocean
Guidi L, Chaffron S, Bittner L, Eveillard D, Larhlimi A, ...
Nature. 2016 Feb 10. doi: 10.1038/nature16942
2016
CYP3A5 mediates basal and acquired therapy resistance in different subtypes of pancreatic ductal adenocarcinoma
Noll EM, Eisen C, Stenzinger A, Espinet E, Muckenhuber A,...
Nat Med. 2016 Feb 8. doi: 10.1038/nm.4038
2016
Active medulloblastoma enhancers reveal subgroup-specific cellular origins
Lin CY, Erkek S, Tong Y, Yin L, Federation AJ, Zapatka M,...
Nature. 2016 Feb 4;530(7588):57-62. doi: 10.1038/nature16546
2016
In vitro cancer cell-ECM interactions inform in vivo cancer treatment
Holle AW, Young JL, Spatz JP
Adv Drug Deliv Rev. 2016 Feb 1;97:270-9. doi: 10.1016/j.addr.2015.10.007
2016
Genetics. IRES unplugged
Gebauer F, Hentze MW
Science. 2016 Jan 15;351(6270):228. doi: 10.1126/science.aad8540
2016
Apolipoprotein E Mediates Evasion From Hepatitis C Virus Neutralizing Antibodies
Fauvelle C, Felmlee DJ, Crouchet E, Lee J, Heydmann L, Le...
Gastroenterology. 2016 Jan;150(1):206-217.e4. doi: 10.1053/j.gastro.2015.09.014
2015
Molecular structures of unbound and transcribing RNA polymerase III
Hoffmann NA, Jakobi AJ, Moreno-Morcillo M, Glatt S, Kosin...
Nature. 2015 Dec 10;528(7581):231-6. doi: 10.1038/nature16143
2015
Inverted light-sheet microscope for imaging mouse pre-implantation development
Strnad P, Gunther S, Reichmann J, Krzic U, Balazs B, de M...
Nat Methods. 2015 Dec 14. doi: 10.1038/nmeth.3690. [Epub ahead of print]
2015
Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota
Forslund K, Hildebrand F, Nielsen T, Falony G, Le Chateli...
Nature. 2015 Dec 10;528(7581):262-6. doi: 10.1038/nature15766
2015
Microscopy-Based High-Content Screening
Boutros M, Heigwer F, Laufer C
Cell. 2015 Dec 3;163(6):1314-25. doi: 10.1016/j.cell.2015.11.007
2015
Brain tumour cells interconnect to a functional and resistant network
Osswald M, Jung E, Sahm F, Solecki G, Venkataramani V, Bl...
Nature. 2015 Dec 3;528(7580):93-8. doi: 10.1038/nature16071
2015
Thermal proteome profiling monitors ligand interactions with cellular membrane proteins
Reinhard FB, Eberhard D, Werner T, Franken H, Childs D, D...
Nat Methods. 2015 Dec;12(12):1129-31. doi: 10.1038/nmeth.3652
2015
Operon structure and cotranslational subunit association direct protein assembly in bacteria
Shieh YW, Minguez P, Bork P, Auburger JJ, Guilbride DL, K...
Science. 2015 Nov 6;350(6261):678-80. doi: 10.1126/science.aac8171
2015
DNA methylome analysis in Burkitt and follicular lymphomas identifies differentially methylated regions linked to somatic mutation and transcriptional control
Kretzmer H, Bernhart SH, Wang W, Haake A, Weniger MA, Ber...
Nat Genet. 2015 Nov;47(11):1316-25. doi: 10.1038/ng.3413
2015
The systematic analysis of protein-lipid interactions comes of age
Saliba AE, Vonkova I, Gavin AC
Nat Rev Mol Cell Biol. 2015 Dec;16(12):753-61. doi: 10.1038/nrm4080
2015
Direct observation of ultrafast collective motions in CO myoglobin upon ligand dissociation
Barends TR, Foucar L, Ardevol A, Nass K, Aquila A, Botha ...
Science. 2015 Oct 23;350(6259):445-50. doi: 10.1126/science.aac5492
2015
Plasticity of an Ultrafast Interaction between Nucleoporins and Nuclear Transport Receptors
Milles S, Mercadante D, Aramburu IV, Jensen MR, Banterle ...
Cell. 2015 Oct 22;163(3):734-45. doi: 10.1016/j.cell.2015.09.047. Epub 2015 Oct 8.
2015
η-Secretase processing of APP inhibits neuronal activity in the hippocampus
Willem M, Tahirovic S, Busche MA, Ovsepian SV, Chafai M, ...
Nature. 2015 Oct 15;526(7573):443-7. doi: 10.1038/nature14864
2015
Architecture of the fungal nuclear pore inner ring complex
Stuwe T, Bley CJ, Thierbach K, Petrovic S, Schilbach S, M...
Science. 2015 Oct 2;350(6256):56-64. doi: 10.1126/science.aac9176
2015
In situ structural analysis of the human nuclear pore complex
von Appen A, Kosinski J, Sparks L, Ori A, DiGuilio AL, Vo...
Nature. 2015 Oct 1;526(7571):140-3. doi: 10.1038/nature15381
2015
Inflammation-Induced Emergency Megakaryopoiesis Driven by Hematopoietic Stem Cell-like Megakaryocyte Progenitors
Haas S, Hansson J, Klimmeck D, Loeffler D, Velten L, Ucke...
Cell Stem Cell. 2015 Oct 1;17(4):422-34. doi: 10.1016/j.stem.2015.07.007. Epub 2015 Aug 20.
2015
Regulation of mitochondrial morphology and function by stearoylation of TFR1
Senyilmaz D, Virtue S, Xu X, Tan CY, Griffin JL, Miller A...
Nature. 2015 Sep 3;525(7567):124-8. doi: 10.1038/nature14601. Epub 2015 Jul 27.
2015
A background Ca2+ entry pathway mediated by TRPC1/TRPC4 is critical for development of pathological cardiac remodelling
Camacho Londoño JE, Tian Q, Hammer K, Schröder L, Camacho...
Eur Heart J. 2015 Sep 1;36(33):2257-66. doi: 10.1093/eurheartj/ehv250
2015
Niche appropriation by Drosophila intestinal stem cell tumours
Patel PH, Dutta D, Edgar BA
Nat Cell Biol. 2015 Sep;17(9):1182-92. doi: 10.1038/ncb3214.
2015
Ultrafast, temporally stochastic STED nanoscopy of millisecond dynamics
Schneider J, Zahn J, Maglione M, Sigrist SJ, Marquard J, ...
Nat Methods. 2015 Sep;12(9):827-30. doi: 10.1038/nmeth.3481
2015
Single-cell transcriptome analysis reveals coordinated ectopic gene-expression patterns in medullary thymic epithelial cells
Brennecke P, Reyes A, Pinto S, Rattay K, Nguyen M, Küchle...
Nat Immunol. 2015 Sep;16(9):933-41. doi: 10.1038/ni.3246
2015
The exosome is recruited to RNA substrates through specific adapter proteins
Thoms M, Thomson E, Baßler J, Gnädig M, Griesel S, Hurt E
Cell. 2015 Aug 27;162(5):1029-38. doi: 10.1016/j.cell.2015.07.060.
2015
Genetic Control of Chromatin States in Humans Involves Local and Distal Chromosomal Interactions
Grubert F, Zaugg JB, Kasowski M, Ursu O, Spacek DV, Marti...
Cell. 2015 Aug 27;162(5):1051-65. doi: 10.1016/j.cell.2015.07.048
2015
Unravelling Spinal Circuits of Pain and Mechanical Allodynia
Gangadharan V, Kuner R
Neuron. 2015 Aug 19;87(4):673-5. doi: 10.1016/j.neuron.2015.08.013
2015
Crucial HSP70 co-chaperone complex unlocks metazoan protein disaggregation
Nillegoda NB, Kirstein J, Szlachcic A, Berynskyy M, Stank...
Nature (published online 5 August 2015), doi:10.1038/nature14884
2015
Modulation of Presynaptic Release Probability by the Vertebrate-Specific Protein Mover
Körber C, Horstmann H, Venkataramani V, Herrmannsdörfer F...
Neuron. 2015 Aug 5;87(3):521-33. doi: 10.1016/j.neuron.2015.07.001. Epub 2015 Jul 23.
2015
VESICULAR TRANSPORT. A structure of the COPI coat and the role of coat proteins in membrane vesicle assembly
Dodonova SO, Diestelkoetter-Bachert P, von Appen A, Hagen...
Science. 2015 Jul 10;349(6244):195-8. doi: 10.1126/science.aab1121
2015
A Conserved Circular Network of Coregulated Lipids Modulates Innate Immune Responses
Köberlin MS, Snijder B, Heinz LX, Baumann CL, Fauster A, ...
Cell. 2015 Jul 2;162(1):170-83. doi: 10.1016/j.cell.2015.05.051
2015
Segregation versus colocalization: orthogonally functionalized binary micropatterned substrates regulate the molecular distribution in focal adhesions
Guasch J, Conings B, Neubauer S, Rechenmacher F, Ende K, ...
Adv Mater. 2015 Jul 1;27(25):3737-47. doi: 10.1002/adma.201500900
2015
BRAIN NETWORKS. Correlated gene expression supports synchronous activity in brain networks
Richiardi J, Altmann A, Milazzo AC, Chang C, Chakravarty ...
Science. 2015 Jun 12;348(6240):1241-4. doi: 10.1126/science.1255905
2015
A Functional Role for VEGFR1 Expressed in Peripheral Sensory Neurons in Cancer Pain
Selvaraj D, Gangadharan V, Michalski CW, Kurejova M, Stös...
Cancer Cell. 2015 Jun 8;27(6):780-96. doi: 10.1016/j.ccell.2015.04.017
2015
Ocean plankton. Determinants of community structure in the global plankton interactome
Lima-Mendez G, Faust K, Henry N, Decelle J, Colin S, Carc...
Science. 2015 May 22;348(6237):1262073. doi: 10.1126/science.1262073
2015
Ocean plankton. Environmental characteristics of Agulhas rings affect interocean plankton transport
Villar E, Farrant GK, Follows M, Garczarek L, Speich S, A...
Science. 2015 May 22;348(6237):1261447. doi: 10.1126/science.1261447
2015
Ocean plankton. Patterns and ecological drivers of ocean viral communities
Brum JR, Ignacio-Espinoza JC, Roux S, Doulcier G, Acinas ...
Science. 2015 May 22;348(6237):1261498. doi: 10.1126/science.1261498
2015
Ocean plankton. Eukaryotic plankton diversity in the sunlit ocean
de Vargas C, Audic S, Henry N, Decelle J, Mahé F, Logares...
Science. 2015 May 22;348(6237):1261605. doi: 10.1126/science.1261605
2015
Suppression of early hematogenous dissemination of human breast cancer cells to bone marrow by retinoic Acid-induced 2
Werner S, Brors B, Eick J, Marques E, Pogenberg V, Parret...
Cancer Discov. 2015 May;5(5):506-19. doi: 10.1158/2159-8290.CD-14-1042
2015
The serine protease inhibitor SerpinA3N attenuates neuropathic pain by inhibiting T cell-derived leukocyte elastase
Vicuña L, Strochlic DE, Latremoliere A, Bali KK, Simonett...
Nat Med. 2015 May;21(5):518-23. doi: 10.1038/nm.3852
2015
Clearance of persistent hepatitis C virus infection in humanized mice using a claudin-1-targeting monoclonal antibody
Mailly L, Xiao F, Lupberger J, Wilson GK, Aubert P, Duong...
Nat Biotechnol. 2015 Mar 23. doi: 10.1038/nbt.3179. [Epub ahead of print]
2015
NAD captureSeq indicates NAD as a bacterial cap for a subset of regulatory RNAs
Cahová H, Winz ML, Höfer K, Nübel K, Jäschke A
Nature. 2015 Mar 19;519(7543):374-7. doi: 10.1038/nature14020
2015
High-throughput fluorescence correlation spectroscopy enables analysis of proteome dynamics in living cells
Wachsmuth M, Conrad C, Bulkescher J, Koch B, Mahen R, Iso...
Nat Biotechnol. 2015 Mar 16. doi: 10.1038/nbt.3146. [Epub ahead of print]
2015
Nuclear architecture dictates HIV-1 integration site selection
Marini B, Kertesz-Farkas A, Ali H, Lucic B, Lisek K, Mang...
Nature. 2015 May 14;521(7551):227-31. doi: 10.1038/nature14226
2015
A molecular mechanotransduction pathway regulates collective migration of epithelial cells
Das T, Safferling K, Rausch S, Grabe N, Boehm H, Spatz JP
Nat Cell Biol. 2015 Feb 23. doi: 10.1038/ncb3115. [Epub ahead of print]
2015
GABA blocks pathological but not acute TRPV1 pain signals
Hanack C, Moroni M, Lima WC, Wende H, Kirchner M, Adelfin...
Cell. 2015 Feb 12;160(4):759-70. doi: 10.1016/j.cell.2015.01.022.
2015
Mutations in the SIX1/2 pathway and the DROSHA/DGCR8 miRNA microprocessor complex underlie high-risk blastemal type Wilms tumors
Wegert J, Ishaque N, Vardapour R, Geörg C, Gu Z, Bieg M, ...
Cancer Cell. 2015 Feb 9;27(2):298-311. doi: 10.1016/j.ccell.2015.01.002
2015
Iron regulatory protein 1 sustains mitochondrial iron loading and function in frataxin deficiency
Martelli A, Schmucker S, Reutenauer L, Mathieu JR, Peysso...
Cell Metab. 2015 Feb 3;21(2):311-22. doi: 10.1016/j.cmet.2015.01.010
2015
Orchestrating high-throughput genomic analysis with Bioconductor
Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carv...
Nat Methods. 2015 Feb;12(2):115-21. doi: 10.1038/nmeth.3252
2015
PIEZO2 is required for mechanotransduction in human stem cell-derived touch receptors
Schrenk-Siemens K, Wende H, Prato V, Song K, Rostock C, L...
Nat Neurosci. 2015 Jan;18(1):10-6. doi: 10.1038/nn.3894. Epub 2014 Dec 3
2015
Structure of the immature HIV-1 capsid in intact virus particles at 8.8 Å resolution
Schur FK, Hagen WJ, Rumlová M, Ruml T, Müller B, Kräussli...
Nature. 2015 Jan 22;517(7535):505-8. doi: 10.1038/nature13838. Epub 2014 Nov 2.
2015
Individual T helper cells have a quantitative cytokine memory
Helmstetter C, Flossdorf M, Peine M, Kupz A, Zhu J, Hegaz...
Immunity. 2015 Jan 20;42(1):108-22. doi: 10.1016/j.immuni.2014.12.018
2015
BAZ2A (TIP5) is involved in epigenetic alterations in prostate cancer and its overexpression predicts disease recurrence
Gu L, Frommel SC, Oakes CC, Simon R, Grupp K, Gerig CY, B...
Nat Genet. 2015 Jan;47(1):22-30. doi: 10.1038/ng.3165. Epub 2014 Dec 8
2014
Protein quality control at the inner nuclear membrane
Khmelinskii A, Blaszczak E, Pantazopoulou M, Fischer B, O...
Nature. 2014 Dec 17;516(7531):410-3. doi: 10.1038/nature14096.
2014
The Yeast ER-Intramembrane Protease Ypf1 Refines Nutrient Sensing by Regulating Transporter Abundance
Avci D, Fuchs S, Schrul B, Fukumori A, Breker M, Frumkin ...
Mol Cell. 2014 Dec 4;56(5):630-40. doi: 10.1016/j.molcel.2014.10.012. Epub 2014 Nov 13.
2014
A somatosensory circuit for cooling perception in mice
Milenkovic N, Zhao WJ, Walcher J, Albert T, Siemens J, Le...
Nat Neurosci. 2014 Nov;17(11):1560-6. doi: 10.1038/nn.3828. Epub 2014 Sep 28
2014
A memory system of negative polarity cues prevents replicative aging
Meitinger F, Khmelinskii A, Morlot S, Kurtulmus B, Palani...
Cell. 2014 Nov 20;159(5):1056-69. doi: 10.1016/j.cell.2014.10.014. Epub 2014 Nov 13
2014
Daclatasvir-like inhibitors of NS5A block early biogenesis of hepatitis C virus-induced membranous replication factories, independent of RNA replication
Berger C, Romero-Brey I, Radujkovic D, Terreux R, Zayas M...
Gastroenterology. 2014 Nov;147(5):1094-105.e25. doi: 10.1053/j.gastro.2014.07.019. Epub 2014 Jul 18
2014
Luminal signalling links cell communication to tissue architecture during organogenesis
Durdu S, Iskar M, Revenu C, Schieber N, Kunze A, Bork P, ...
Nature. 2014 Nov 6;515(7525):120-4. doi: 10.1038/nature13852. Epub 2014 Oct 22
2014
Structural biology: Enzyme-chromatin complex visualized
Müller J, Müller CW
Nature. 2014 Oct 30;514(7524):572-3. doi: 10.1038/514572a
2014
PSFj: know your fluorescence microscope
Theer P, Mongis C, Knop M
Nat Methods. 2014 Oct;11(10):981-2. doi: 10.1038/nmeth.3102
2014
Mitochondria tether protein trash to rejuvenate cellular environments
Mogk A, Bukau B
Cell. 2014 Oct 23;159(3):471-2. doi: 10.1016/j.cell.2014.10.007
2014
SUMOylation-dependent LRH-1/PROX1 interaction promotes atherosclerosis by decreasing hepatic reverse cholesterol transport
Stein S, Oosterveer MH, Mataki C, Xu P, Lemos V, Havinga ...
Cell Metab. 2014 Oct 7;20(4):603-13. doi: 10.1016/j.cmet.2014.07.023
2014
Photo-cross-linking and high-resolution mass spectrometry for assignment of RNA-binding sites in RNA-binding proteins
Kramer K, Sachsenberg T, Beckmann BM, Qamar S, Boon KL, H...
Nat Methods. 2014 Oct;11(10):1064-70. doi: 10.1038/nmeth.3092
2014
In vivo RNAi screening identifies a mechanism of sorafenib resistance in liver cancer
Rudalska R, Dauch D, Longerich T, McJunkin K, Wuestefeld ...
Nat Med. 2014 Oct;20(10):1138-46. doi: 10.1038/nm.3679
2014
Identification of regulatory networks in HSCs and their immediate progeny via integrated proteome, transcriptome, and DNA Methylome analysis
Cabezas-Wallscheid N, Klimmeck D, Hansson J, Lipka DB, Re...
Cell Stem Cell. 2014 Oct 2;15(4):507-22. doi: 10.1016/j.stem.2014.07.005
2014
Biochemistry and Medicinal Chemistry of the Dengue Virus Protease
Nitsche C, Holloway S, Schirmeister T, Klein CD
Chem Rev. 2014 Sep 30. [Epub ahead of print]
2014
Uniquantal release through a dynamic fusion pore is a candidate mechanism of hair cell exocytosis
Chapochnikov NM, Takago H, Huang CH, Pangršič T, Khimich ...
Neuron. 2014 Sep 17;83(6):1389-403. doi: 10.1016/j.neuron.2014.08.003
2014
Axon-carrying dendrites convey privileged synaptic input in hippocampal neurons
Thome C, Kelly T, Yanez A, Schultz C, Engelhardt M, Cambr...
Neuron. 2014 Sep 17;83(6):1418-30. doi: 10.1016/j.neuron.2014.08.013. Epub 2014 Sep 4
2014
The symptom complex of familial sinus node dysfunction and myocardial noncompaction is associated with mutations in the HCN4 channel
Schweizer PA, Schröter J, Greiner S, Haas J, Yampolsky P,...
J Am Coll Cardiol. 2014 Aug 26;64(8):757-67. doi: 10.1016/j.jacc.2014.06.1155
2014
Nodal signalling determines biradial asymmetry in Hydra
Watanabe H, Schmidt HA, Kuhn A, Höger SK, Kocagöz Y, Laum...
Nature. 2014 Nov 6;515(7525):112-5. doi: 10.1038/nature13666
2014
Adding new dimensions: towards an integrative understanding of HIV-1 spread
Fackler OT, Murooka TT, Imle A, Mempel TR
Nat Rev Microbiol. 2014 Aug;12(8):563-74. doi: 10.1038/nrmicro3309
2014
An integrated catalog of reference genes in the human gut microbiome
Li J, Jia H, Cai X, Zhong H, Feng Q, Sunagawa S, Arumugam...
Nat Biotechnol. 2014 Aug;32(8):834-41. doi: 10.1038/nbt.2942. Epub 2014 Jul 6
2014
Identification and assembly of genomes and genetic elements in complex metagenomic samples without using reference genomes
Nielsen HB, Almeida M, Juncker AS, Rasmussen S, Li J, Sun...
Nat Biotechnol. 2014 Aug;32(8):822-8. doi: 10.1038/nbt.2939. Epub 2014 Jul 6
2014
Neuropsychosocial profiles of current and future adolescent alcohol misusers
Whelan R, Watts R, Orr CA, Althoff RR, Artiges E, Banasch...
Nature. 2014 Aug 14;512(7513):185-9. doi: 10.1038/nature13402. Epub 2014 Jul 2
2014
DENR-MCT-1 promotes translation re-initiation downstream of uORFs to control tissue growth
Schleich S, Strassburger K, Janiesch PC, Koledachkina T, ...
Nature. 2014 Aug 14;512(7513):208-12. doi: 10.1038/nature13401. Epub 2014 Jul 6
2014
Diverse intracellular pathogens activate type III interferon expression from peroxisomes
Odendall C, Dixit E, Stavru F, Bierne H, Franz KM, Durbin...
Nat Immunol. 2014 Aug;15(8):717-26. doi: 10.1038/ni.2915. Epub 2014 Jun 22
2014
Lipidomics: analysis of the lipid composition of cells and subcellular organelles by electrospray ionization mass spectrometry
Brügger B
Annu Rev Biochem. 2014;83:79-98. doi: 10.1146/annurev-biochem-060713-035324. Epub 2014 Mar 3
2014
Coexpressed auxiliary subunits exhibit distinct modulatory profiles on AMPA receptor function
Khodosevich K, Jacobi E, Farrow P, Schulmann A, Rusu A, Z...
Neuron. 2014 Aug 6;83(3):601-15. doi: 10.1016/j.neuron.2014.07.004. Epub 2014 Jul 24
2014
Resistance of Ferroportin to Hepcidin Binding causes Exocrine Pancreatic Failure and Fatal Iron Overload
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