CellNetworks - Most Important

2019

Antibiotics-induced monodominance of a novel gut bacterial order

Hildebrand F, Moitinho-Silva L, Blasche S, Jahn MT, Gossm...

Gut. 2019 Jan 18. pii: gutjnl-2018-317715. doi: 10.1136/gutjnl-2018-317715

2019

Association of a Schizophrenia-Risk Nonsynonymous Variant With Putamen Volume in Adolescents: A Voxelwise and Genome-Wide Association Study

Luo Q, Chen Q, Wang W, Desrivières S, Quinlan EB, Jia T, ...

JAMA Psychiatry. 2019 Jan 16. doi: 10.1001/jamapsychiatry.2018.4126

2019

T cell receptor-triggered nuclear actin network formation drives CD4+ T cell effector functions

Tsopoulidis N, Kaw S, Laketa V, Kutscheidt S, Baarlink C,...

Sci Immunol. 2019 Jan 4;4(31). pii: eaav1987. doi: 10.1126/sciimmunol.aav1987

2018

Eukaryotic Ribosome Assembly

Baßler J, Hurt E

Annu Rev Biochem. 2018 Dec 19. doi: 10.1146/annurev-biochem-013118-110817

2018

Immune genes are primed for robust transcription by proximal long noncoding RNAs located in nuclear compartments

Fanucchi S, Fok ET, Dalla E, Shibayama Y, Börner K, Chang...

Nat Genet. 2018 Dec 10. doi: 10.1038/s41588-018-0298-2

2018

Mechanisms of Cotranslational Maturation of Newly Synthesized Proteins

Kramer G, Shiber A, Bukau B

Annu Rev Biochem. 2018 Dec 3. doi: 10.1146/annurev-biochem-013118-111717

2018

The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest

Trendel J, Schwarzl T, Horos R, Prakash A, Bateman A, Hen...

Cell. 2018 Dec 1. pii: S0092-8674(18)31463-6. doi: 10.1016/j.cell.2018.11.004

2018

Membrane-Associated RNA-Binding Proteins Orchestrate Organelle-Coupled Translation

Béthune J, Jansen RP, Feldbrügge M, Zarnack K

Trends Cell Biol. 2018 Nov 12. pii: S0962-8924(18)30185-5. doi: 10.1016/j.tcb.2018.10.005

2018

Experimental and computational framework for a dynamic protein atlas of human cell division

Cai Y, Hossain MJ, Hériché JK, Politi AZ, Walther N, Koch...

Nature. 2018 Sep;561(7723):411-415. doi: 10.1038/s41586-018-0518-z

2018

Cotranslational assembly of protein complexes in eukaryotes revealed by ribosome profiling

Shiber A, Döring K, Friedrich U, Klann K, Merker D, Zedan...

Nature. 2018 Sep;561(7722):268-272. doi: 10.1038/s41586-018-0462-y.

2018

Modified aptamers enable quantitative sub-10-nm cellular DNA-PAINT imaging

Strauss S, Nickels PC, Strauss MT, Jimenez Sabinina V, El...

Nat Methods. 2018 Sep;15(9):685-688. doi: 10.1038/s41592-018-0105-0

2018

Systematic Nanoscale Analysis of Endocytosis Links Efficient Vesicle Formation to Patterned Actin Nucleation

Mund M, van der Beek JA, Deschamps J, Dmitrieff S, Hoess ...

Cell. 2018 Aug 9;174(4):884-896.e17. doi: 10.1016/j.cell.2018.06.032

2018

Dual-spindle formation in zygotes keeps parental genomes apart in early mammalian embryos

Reichmann J, Nijmeijer B, Hossain MJ, Eguren M, Schneider...

Science. 2018 Jul 13;361(6398):189-193. doi: 10.1126/science.aar7462.

2018

Real-time 3D single-molecule localization using experimental point spread functions

Li Y, Mund M, Hoess P, Deschamps J, Matti U, Nijmeijer B,...

Nat Methods. 2018 May;15(5):367-369. doi: 10.1038/nmeth.4661.

2018

Protein Disaggregation in Multicellular Organisms

Nillegoda NB, Wentink AS, Bukau B

Trends Biochem Sci. 2018 Apr;43(4):285-300. doi: 10.1016/j.tibs.2018.02.003

2018

The Human Gut Microbiome: From Association to Modulation

Schmidt TSB, Raes J, Bork P

Cell. 2018 Mar 8;172(6):1198-1215. doi: 10.1016/j.cell.2018.02.044

2018

Inhibition of Endothelial Notch Signaling Impairs Fatty Acid Transport and Leads to Metabolic and Vascular Remodeling of the Adult Heart

Jabs M, Rose AJ, Lehmann LH, Taylor J, Moll I, Sijmonsma ...

Circulation. 2018 Jan 20. pii: CIRCULATIONAHA.117.029733. doi: 10.1161/CIRCULATIONAHA.117.029733

2018

A brave new world of RNA-binding proteins

Hentze MW, Castello A, Schwarzl T, Preiss T

Nat Rev Mol Cell Biol. 2018 Jan 17. doi: 10.1038/nrm.2017.130

2018

Sequential bottom-up assembly of mechanically stabilized synthetic cells by microfluidics

Weiss M, Frohnmayer JP, Benk LT, Haller B, Janiesch JW, H...

Nat Mater. 2018 Jan;17(1):89-96. doi: 10.1038/nmat5005.

2018

From Maps to Multi-dimensional Network Mechanisms of Mental Disorders

Braun U, Schaefer A, Betzel RF, Tost H, Meyer-Lindenberg ...

Neuron. 2018 Jan 3;97(1):14-31. doi: 10.1016/j.neuron.2017.11.007.

2018

From Maps to Multi-dimensional Network Mechanisms of Mental Disorders

Braun U, Schaefer A, Betzel RF, Tost H, Meyer-Lindenberg ...

Neuron. 2018 Jan 3;97(1):14-31. doi: 10.1016/j.neuron.2017.11.007.

2017

Molecular Mechanism of J-Domain-Triggered ATP Hydrolysis by Hsp70 Chaperones

Kityk R, Kopp J, Mayer MP

Mol Cell. 2017 Dec 27. pii: S1097-2765(17)30931-0. doi: 10.1016/j.molcel.2017.12.003.

2017

Visualizing the Assembly Pathway of Nucleolar Pre-60S Ribosomes

Kater L, Thoms M, Barrio-Garcia C, Cheng J, Ismail S, Ahm...

Cell. 2017 Dec 14;171(7):1599-1610.e14. doi: 10.1016/j.cell.2017.11.039.

2017

Mechanobiology by the numbers: a close relationship between biology and physics

Schwarz US

Nat Rev Mol Cell Biol. 2017 Dec;18(12):711-712. doi: 10.1038/nrm.2017.109.

2017

Fluorescence nanoscopy in cell biology

Sahl SJ, Hell SW, Jakobs S

Nat Rev Mol Cell Biol. 2017 Nov;18(11):685-701. doi: 10.1038/nrm.2017.71

2017

Cell mechanics: When tissues collide

Schwarz US, Ziebert F

Nat Mater. 2017 Oct;16(10):972-973. doi: 10.1038/nmat4988.

2017

Brain imaging tests for chronic pain: medical, legal and ethical issues and recommendations

Davis KD, Flor H, Greely HT, Iannetti GD, Mackey S, Plone...

Nat Rev Neurol. 2017 Oct;13(10):624-638. doi: 10.1038/nrneurol.2017.122

2017

A pathway from midcingulate cortex to posterior insula gates nociceptive hypersensitivity

Tan LL, Pelzer P, Heinl C, Tang W, Gangadharan V, Flor H,...

Nat Neurosci. 2017 Sep 18. doi: 10.1038/nn.4645

2017

Single-molecule FRET reveals the energy landscape of the full-length SAM-I riboswitch

Manz C, Kobitski AY, Samanta A, Keller BG, Jäschke A, Nie...

Nat Chem Biol. 2017 Sep 18. doi: 10.1038/nchembio.2476

2017

Solid-phase reverse transfection for intracellular delivery of functionally active proteins

Bulkescher R, Starkuviene V, Erfle H

Genome Res. 2017 Sep 5. doi: 10.1101/gr.215103.116

2017

Functional insights into pathogen biology from 3D electron microscopy

Cyrklaff M, Frischknecht F, Kudryashev M

FEMS Microbiol Rev. 2017 Aug 22. doi: 10.1093/femsre/fux041

2017

M3: an integrative framework for structure determination of molecular machines

Karaca E, Rodrigues JPGLM, Graziadei A, Bonvin AMJJ, Carl...

Nat Methods. 2017 Aug 14. doi: 10.1038/nmeth.4392

2017

Polylox barcoding reveals haematopoietic stem cell fates realized in vivo

Pei W, Feyerabend TB, Rössler J, Wang X, Postrach D, Busc...

Nature. 2017 Aug 24;548(7668):456-460. doi: 10.1038/nature23653.

2017

DNMT and HDAC inhibitors induce cryptic transcription start sites encoded in long terminal repeats

Brocks D, Schmidt CR, Daskalakis M, Jang HS, Shah NM, Li ...

Nat Genet. 2017 Jul;49(7):1052-1060. doi: 10.1038/ng.3889

2017

Minimum information about a single amplified genome (MISAG) and a metagenome-assembled genome (MIMAG) of bacteria and archaea

Bowers RM, Kyrpides NC, Stepanauskas R, Harmon-Smith M, D...

Nat Biotechnol. 2017 Aug 8;35(8):725-731. doi: 10.1038/nbt.3893

2017

Chromophore twisting in the excited state of a photoswitchable fluorescent protein captured by time-resolved serial femtosecond crystallography

Coquelle, N.; Sliwa, M.; Woodhouse, J.; Schirò, G.; Adam,...

Nature Chemistry. 2017 Jul 27. doi:10.1038/nchem.2853.

2017

The whole-genome landscape of medulloblastoma subtypes

Northcott PA, Buchhalter I, Morrissy A, Hovestadt V, Weis...

Nature. 2017 Jul 19;547(7663):311-317. doi: 10.1038/nature22973

2017

Profiling Ssb-Nascent Chain Interactions Reveals Principles of Hsp70-Assisted Folding

Döring K, Ahmed N, Riemer T, Suresh HG, Vainshtein Y, Hab...

Cell. 2017 Jul 13;170(2):298-311.e20. doi: 10.1016/j.cell.2017.06.038

2017

Single-Molecule Localization Microscopy in Eukaryotes

Sauer M, Heilemann M

Chem Rev. 2017 Jun 14;117(11):7478-7509. doi: 10.1021/acs.chemrev.6b00667

2017

Thiolutin is a zinc chelator that inhibits the Rpn11 and other JAMM metalloproteases

Lauinger L, Li J, Shostak A, Cemel IA, Ha N, Zhang Y, Mer...

Nat Chem Biol. 2017 Jul;13(7):709-714. doi: 10.1038/nchembio.2370.

2017

Broad-spectrum agents for flaviviral infections: dengue, Zika and beyond

Boldescu V, Behnam MAM, Vasilakis N, Klein CD

Nat Rev Drug Discov. 2017 May 5. doi: 10.1038/nrd.2017.33

2017

RETINOBLASTOMA RELATED1 mediates germline entry in Arabidopsis

Zhao X, Bramsiepe J, Van Durme M, Komaki S, Prusicki MA, ...

Science. 2017 Apr 28;356(6336). pii: eaaf6532. doi: 10.1126/science.aaf6532.

2017

Endoplasmic-reticulum-mediated microtubule alignment governs cytoplasmic streaming

Kimura K, Mamane A, Sasaki T, Sato K, Takagi J, Niwayama ...

Nat Cell Biol. 2017 Apr;19(4):399-406. doi: 10.1038/ncb3490.

2017

Prefrontal cortical control of a brainstem social behavior circuit

Franklin TB, Silva BA, Perova Z, Marrone L, Masferrer ME,...

Nat Neurosci. 2017 Feb;20(2):260-270. doi: 10.1038/nn.4470

2017

The nuclear pore complex: understanding its function through structural insight

Beck M, Hurt E

Nat Rev Mol Cell Biol. 2017 Feb;18(2):73-89. doi: 10.1038/nrm.2016.147.

2017

Structural plasticity and reorganisation in chronic pain

Kuner R, Flor H

Nat Rev Neurosci. 2017 Jan 20;18(2):113. doi: 10.1038/nrn.2017.5

2017

Defining the brain circuits involved in psychiatric disorders: IMI-NEWMEDS

Artigas F, Schenker E, Celada P, Spedding M, Lladó-Pelfor...

Nat Rev Drug Discov. 2017 Jan;16(1):1-2. doi: 10.1038/nrd.2016.205.

2017

Progress in imaging methods: insights gained into Plasmodium biology

De Niz M, Burda PC, Kaiser G, Del Portillo HA, Spielmann ...

Nat Rev Microbiol. 2017 Jan;15(1):37-54. doi: 10.1038/nrmicro.2016.158

2016

The structure and flexibility of conical HIV-1 capsids determined within intact virions

Mattei S, Glass B, Hagen WJ, Kräusslich HG, Briggs JA

Science. 2016 Dec 16;354(6318):1434-1437.

2016

Genetic code expansion for multiprotein complex engineering

Koehler C, Sauter PF, Wawryszyn M, Girona GE, Gupta K, La...

Nat Methods. 2016 Dec;13(12):997-1000. doi: 10.1038/nmeth.4032.

2016

Transcriptional programs that control expression of the autoimmune regulator gene Aire

Herzig Y, Nevo S, Bornstein C, Brezis MR, Ben-Hur S, Shke...

Nat Immunol. 2017 Feb;18(2):161-172. doi: 10.1038/ni.3638

2016

Nuclear landscape of HIV-1 infection and integration

Lusic M, Siliciano RF

Nat Rev Microbiol. 2016 Dec 12. doi: 10.1038/nrmicro.2016.162

2016

Temporal accumulation analysis provides simplified artifact-free analysis of membrane-protein nanoclusters

Spahn C, Herrmannsdörfer F, Kuner T, Heilemann M

Nat Methods. 2016 Nov 29;13(12):963-964. doi: 10.1038/nmeth.4065.

2016

Alternative modes of client binding enable functional plasticity of Hsp70

Mashaghi A, Bezrukavnikov S, Minde DP, Wentink AS, Kityk ...

Nature. 2016 Nov 17;539(7629):448-451. doi: 10.1038/nature20137

2016

Transient RNA-DNA Hybrids Are Required for Efficient Double-Strand Break Repair

Ohle C, Tesorero R, Schermann G, Dobrev N, Sinning I, Fis...

Cell. 2016 Nov 3;167(4):1001-1013.e7. doi: 10.1016/j.cell.2016.10.001

2016

Expanding the Circuitry of Pluripotency by Selective Isolation of Chromatin-Associated Proteins

Rafiee MR, Girardot C, Sigismondo G, Krijgsveld J

Mol Cell. 2016 Nov 3;64(3):624-635. doi: 10.1016/j.molcel.2016.09.019.

2016

Exploiting Noncovalent Interactions in an Imine-Based Covalent Organic Framework for Quercetin Delivery

Vyas VS, Vishwakarma M, Moudrakovski I, Haase F, Savasci ...

Adv Mater. 2016 Oct;28(39):8749-8754. doi: 10.1002/adma.201603006.

2016

Ecogenomics and potential biogeochemical impacts of globally abundant ocean viruses

Roux S1, Brum JR1, Dutilh BE2,3,4, Sunagawa S5, Duhaime M...

Nature. 2016 Sep 29;537(7622):689-693. doi: 10.1038/nature19366

2016

LOVTRAP: an optogenetic system for photoinduced protein dissociation

Wang H, Vilela M, Winkler A, Tarnawski M, Schlichting I, ...

Nat Methods. 2016 Sep;13(9):755-8. doi: 10.1038/nmeth.3926.

2016

The TRPM2 channel is a hypothalamic heat sensor that limits fever and can drive hypothermia

Song K, Wang H, Kamm GB, Pohle J, Reis FC, Heppenstall P,...

Science. 2016 Sep 23;353(6306):1393-1398.

2016

Acetylation-Dependent Control of Global Poly(A) RNA Degradation by CBP/p300 and HDAC1/2

Sharma S, Poetz F, Bruer M, Ly-Hartig TB, Schott J, Sérap...

Mol Cell. 2016 Sep 15;63(6):927-38. doi: 10.1016/j.molcel.2016.08.030.

2016

Vascular endothelial growth factor: a neurovascular target in neurological diseases

Lange C, Storkebaum E, de Almodóvar CR, Dewerchin M, Carm...

Nat Rev Neurol. 2016 Aug;12(8):439-54. doi: 10.1038/nrneurol.2016.88

2016

Global profiling of SRP interaction with nascent polypeptides

Schibich D, Gloge F, Pöhner I, Björkholm P, Wade RC, von ...

Nature. 2016 Aug 11;536(7615):219-23

2016

Tumour-cell-induced endothelial cell necroptosis via death receptor 6 promotes metastasis

Strilic B, Yang L, Albarrán-Juárez J, Wachsmuth L, Han K,...

Nature. 2016 Aug 11;536(7615):215-8

2016

Crystal structure of Zika virus NS2B-NS3 protease in complex with a boronate inhibitor

Lei J, Hansen G, Nitsche C, Klein CD, Zhang L, Hilgenfeld R

Science. 2016 Jul 29;353(6298):503-5. doi: 10.1126/science.aag2419

2016

Pre-assembled Nuclear Pores Insert into the Nuclear Envelope during Early Development

Hampoelz B, Mackmull MT, Machado P, Ronchi P, Bui KH, Sch...

Cell. 2016 Jul 28;166(3):664-78. doi: 10.1016/j.cell.2016.06.015

2016

Molecular biology: A surprise beginning for RNA

Höfer K, Jäschke A

Nature. 2016 Jul 21;535(7612):359-60

2016

An atomic model of HIV-1 capsid-SP1 reveals structures regulating assembly and maturation

Schur FK, Obr M, Hagen WJ, Wan W, Jakobi AJ, Kirkpatrick ...

Science. 2016 Jul 14. pii: aaf9620

2016

Architecture of the 90S Pre-ribosome: A Structural View on the Birth of the Eukaryotic Ribosome

Kornprobst M, Turk M, Kellner N, Cheng J, Flemming D, Koš...

Cell. 2016 Jul 14;166(2):380-93. doi: 10.1016/j.cell.2016.06.014

2016

In Vivo Tracking of Human Hematopoiesis Reveals Patterns of Clonal Dynamics during Early and Steady-State Reconstitution Phases

Biasco L, Pellin D, Scala S, Dionisio F, Basso-Ricci L, L...

Cell Stem Cell. 2016 Jul 7;19(1):107-19. doi: 10.1016/j.stem.2016.04.016

2016

Data-driven hypothesis weighting increases detection power in genome-scale multiple testing

Ignatiadis N, Klaus B, Zaugg JB, Huber W

Nat Methods. 2016 Jul;13(7):577-80. doi: 10.1038/nmeth.3885

2016

Spatially segregated feedforward and feedback neurons support differential odor processing in the lateral entorhinal cortex

Leitner FC, Melzer S, Lütcke H, Pinna R, Seeburg PH, Helm...

Nat Neurosci. 2016 Jul;19(7):935-44. doi: 10.1038/nn.4303

2016

Identifying multimodal signatures associated with symptom clusters: the example of the IMAGEMEND project

Frangou S, Schwarz E, Meyer-Lindenberg A, IMAGEMEND

World Psychiatry. 2016 Jun;15(2):179-80. doi: 10.1002/wps.20334.

2016

Altering the course of schizophrenia: progress and perspectives

Millan MJ, Andrieux A, Bartzokis G, Cadenhead K, Dazzan P...

Nat Rev Drug Discov. 2016 Jul;15(7):485-515. doi: 10.1038/nrd.2016.28.

2016

In Vivo Hepatic Reprogramming of Myofibroblasts with AAV Vectors as a Therapeutic Strategy for Liver Fibrosis

Rezvani M, Español-Suñer R, Malato Y, Dumont L, Grimm AA,...

Cell Stem Cell. 2016 Jun 2;18(6):809-16. doi: 10.1016/j.stem.2016.05.005

2016

Automated structure modeling of large protein assemblies using crosslinks as distance restraints

Ferber M, Kosinski J, Ori A, Rashid UJ, Moreno-Morcillo M...

Nat Methods. 2016 Jun;13(6):515-20. doi: 10.1038/nmeth.3838

2016

Automated structure modeling of large protein assemblies using crosslinks as distance restraints

Ferber M, Kosinski J, Ori A, Rashid UJ, Moreno-Morcillo M...

Nat Methods. 2016 Jun;13(6):515-20. doi: 10.1038/nmeth.3838

2016

Standardized benchmarking in the quest for orthologs

Altenhoff AM, Boeckmann B, Capella-Gutierrez S, Dalquen D...

Nat Methods. 2016 May;13(5):425-30. doi: 10.1038/nmeth.3830

2016

Molecular architecture of the inner ring scaffold of the human nuclear pore complex

Kosinski J, Mosalaganti S, von Appen A, Teimer R, DiGuili...

Science. 2016 Apr 15;352(6283):363-5. doi: 10.1126/science.aaf0643

2016

Molecular architecture of the inner ring scaffold of the human nuclear pore complex

Kosinski J, Mosalaganti S, von Appen A, Teimer R, DiGuili...

Science. 2016 Apr 15;352(6283):363-5. doi: 10.1126/science.aaf0643

2016

A new population of parvocellular oxytocin neurons controlling magnocellular neuron activity and inflammatory pain processing

Eliava M, Melchior M, Knobloch-Bollmann HS, Wahis J, da S...

NEURON 2016 Mar 16;89(6):1291-1304. doi: 10.1016/j.neuron.2016.01.041.

2016

SuReSim: simulating localization microscopy experiments from ground truth models

Venkataramani V, Herrmannsdörfer F, Heilemann M, Kuner T.

Nat Methods. 2016 Apr;13(4):319-21. doi: 10.1038/nmeth.3775. Epub 2016 Feb 29.

2016

Complex Interdependence Regulates Heterotypic Transcription Factor Distribution and Coordinates Cardiogenesis

Luna-Zurita L, Stirnimann CU, Glatt S, Kaynak BL, Thomas ...

Cell. 2016 Feb 25;164(5):999-1014. doi: 10.1016/j.cell.2016.01.004

2016

Myc Depletion Induces a Pluripotent Dormant State Mimicking Diapause

Scognamiglio R, Cabezas-Wallscheid N, Thier MC, Altamura ...

Cell. 2016 Feb 11;164(4):668-80. doi: 10.1016/j.cell.2015.12.033

2016

Plankton networks driving carbon export in the oligotrophic ocean

Guidi L, Chaffron S, Bittner L, Eveillard D, Larhlimi A, ...

Nature. 2016 Feb 10. doi: 10.1038/nature16942

2016

CYP3A5 mediates basal and acquired therapy resistance in different subtypes of pancreatic ductal adenocarcinoma

Noll EM, Eisen C, Stenzinger A, Espinet E, Muckenhuber A,...

Nat Med. 2016 Feb 8. doi: 10.1038/nm.4038

2016

Active medulloblastoma enhancers reveal subgroup-specific cellular origins

Lin CY, Erkek S, Tong Y, Yin L, Federation AJ, Zapatka M,...

Nature. 2016 Feb 4;530(7588):57-62. doi: 10.1038/nature16546

2016

In vitro cancer cell-ECM interactions inform in vivo cancer treatment

Holle AW, Young JL, Spatz JP

Adv Drug Deliv Rev. 2016 Feb 1;97:270-9. doi: 10.1016/j.addr.2015.10.007

2016

Femtosecond and nanometre visualization of structural dynamics in superheated nanoparticles

Gorkhover T, Schorb S, Coffee R, Adolph M, Foucar L, Rupp...

Nat Photonics. 2016 Jan 25; 10, 93–97, doi:10.1038/nphoton.2015.264.

2016

Genetics. IRES unplugged

Gebauer F, Hentze MW

Science. 2016 Jan 15;351(6270):228. doi: 10.1126/science.aad8540

2016

Identification and validation of biomarkers for autism spectrum disorders

Loth E, Spooren W, Ham LM, Isaac MB, Auriche-Benichou C, ...

Nat Rev Drug Discov. 2016 Jan;15(1):70-3. doi: 10.1038/nrd.2015.7.

2016

Apolipoprotein E Mediates Evasion From Hepatitis C Virus Neutralizing Antibodies

Fauvelle C, Felmlee DJ, Crouchet E, Lee J, Heydmann L, Le...

Gastroenterology. 2016 Jan;150(1):206-217.e4. doi: 10.1053/j.gastro.2015.09.014

2015

Molecular structures of unbound and transcribing RNA polymerase III

Hoffmann NA, Jakobi AJ, Moreno-Morcillo M, Glatt S, Kosin...

Nature. 2015 Dec 10;528(7581):231-6. doi: 10.1038/nature16143

2015

Inverted light-sheet microscope for imaging mouse pre-implantation development

Strnad P, Gunther S, Reichmann J, Krzic U, Balazs B, de M...

Nat Methods. 2015 Dec 14. doi: 10.1038/nmeth.3690. [Epub ahead of print]

2015

Inverted light-sheet microscope for imaging mouse pre-implantation development

Strnad P, Gunther S, Reichmann J, Krzic U, Balazs B, de M...

Nat Methods. 2015 Dec 14. doi: 10.1038/nmeth.3690. [Epub ahead of print]

2015

Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota

Forslund K, Hildebrand F, Nielsen T, Falony G, Le Chateli...

Nature. 2015 Dec 10;528(7581):262-6. doi: 10.1038/nature15766

2015

Microscopy-Based High-Content Screening

Boutros M, Heigwer F, Laufer C

Cell. 2015 Dec 3;163(6):1314-25. doi: 10.1016/j.cell.2015.11.007

2015

Brain tumour cells interconnect to a functional and resistant network

Osswald M, Jung E, Sahm F, Solecki G, Venkataramani V, Bl...

Nature. 2015 Dec 3;528(7580):93-8. doi: 10.1038/nature16071

2015

Thermal proteome profiling monitors ligand interactions with cellular membrane proteins

Reinhard FB, Eberhard D, Werner T, Franken H, Childs D, D...

Nat Methods. 2015 Dec;12(12):1129-31. doi: 10.1038/nmeth.3652

2015

NEMO Prevents Steatohepatitis and Hepatocellular Carcinoma by Inhibiting RIPK1 Kinase Activity-Mediated Hepatocyte Apoptosis

Kondylis V, Polykratis A, Ehlken H, Ochoa-Callejero L, St...

Cancer Cell. 2015 Nov 9;28(5):582-598. doi: 10.1016/j.ccell.2015.10.001

2015

Operon structure and cotranslational subunit association direct protein assembly in bacteria

Shieh YW, Minguez P, Bork P, Auburger JJ, Guilbride DL, K...

Science. 2015 Nov 6;350(6261):678-80. doi: 10.1126/science.aac8171

2015

DNA methylome analysis in Burkitt and follicular lymphomas identifies differentially methylated regions linked to somatic mutation and transcriptional control

Kretzmer H, Bernhart SH, Wang W, Haake A, Weniger MA, Ber...

Nat Genet. 2015 Nov;47(11):1316-25. doi: 10.1038/ng.3413

2015

The systematic analysis of protein-lipid interactions comes of age

Saliba AE, Vonkova I, Gavin AC

Nat Rev Mol Cell Biol. 2015 Dec;16(12):753-61. doi: 10.1038/nrm4080

2015

Direct observation of ultrafast collective motions in CO myoglobin upon ligand dissociation

Barends TR, Foucar L, Ardevol A, Nass K, Aquila A, Botha ...

Science. 2015 Oct 23;350(6259):445-50. doi: 10.1126/science.aac5492

2015

Plasticity of an Ultrafast Interaction between Nucleoporins and Nuclear Transport Receptors

Milles S, Mercadante D, Aramburu IV, Jensen MR, Banterle ...

Cell. 2015 Oct 22;163(3):734-45. doi: 10.1016/j.cell.2015.09.047. Epub 2015 Oct 8.

2015

η-Secretase processing of APP inhibits neuronal activity in the hippocampus

Willem M, Tahirovic S, Busche MA, Ovsepian SV, Chafai M, ...

Nature. 2015 Oct 15;526(7573):443-7. doi: 10.1038/nature14864

2015

Architecture of the fungal nuclear pore inner ring complex

Stuwe T, Bley CJ, Thierbach K, Petrovic S, Schilbach S, M...

Science. 2015 Oct 2;350(6256):56-64. doi: 10.1126/science.aac9176

2015

In situ structural analysis of the human nuclear pore complex

von Appen A, Kosinski J, Sparks L, Ori A, DiGuilio AL, Vo...

Nature. 2015 Oct 1;526(7571):140-3. doi: 10.1038/nature15381

2015

Inflammation-Induced Emergency Megakaryopoiesis Driven by Hematopoietic Stem Cell-like Megakaryocyte Progenitors

Haas S, Hansson J, Klimmeck D, Loeffler D, Velten L, Ucke...

Cell Stem Cell. 2015 Oct 1;17(4):422-34. doi: 10.1016/j.stem.2015.07.007. Epub 2015 Aug 20.

2015

Regulation of mitochondrial morphology and function by stearoylation of TFR1

Senyilmaz D, Virtue S, Xu X, Tan CY, Griffin JL, Miller A...

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Structural basis of the nic96 subcomplex organization in the nuclear pore channel

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Mol Cell. 2008 Jan 18;29(1):46-55.

2008

Nutritional control of protein biosynthetic capacity by insulin via Myc in Drosophila

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2008

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2007

Semen-derived amyloid fibrils drastically enhance HIV Infection.

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Cell. 2007 Dec 14;131(6):1059-71.

2007

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2007

Therapeutic application of RNAi: is mRNA targeting finally ready for prime time?

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Competition for cytokines: T(reg) cells take all

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Nat Immunol. 2007 Dec;8(12):1285-7. doi: 10.1038/ni1207-1285

2007

Concepts in SUMOylation: a decade on.

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Nat Rev Mol Cell Biol. 2007 Dec;8(12):947-56.

2007

Rapid control of protein level in the apicomplexan Toxoplasma gondii.

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Nat Methods. 2007 Dec;4(12):1003-5.

2007

Genome-wide experimental determination of barriers to horizontal gene transfer

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Nat Cell Biol. 2007 Nov;9(11):1219-20

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Nat Rev Mol Cell Biol. 2007 Oct;8(10):761-73.

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Exonuclease-1 deletion impairs DNA damage signaling and prolongs lifespan of telomere-dysfunctional mice

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2007

Arx1 functions as alternative nuclear export receptor for the 60S pre-ribosomal subunit

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Mol Cell. 2007 Sep 7;27(5):767-79.

2007

The lipid droplet is an important organelle for hepatitis C virus production.

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2007

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Nat Immunol. 2007 Aug;8(8):864-72

2007

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2007

Maximal chromosome compaction occurs by axial shortening in anaphase and depends on Aurora kinase.

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Nat Cell Biol. 2007 Jul;9(7):822-31

2007

Molecular basis for the functional interaction of dynein light chain with the nuclear pore complex

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Nat Cell Biol. 2007 Jul;9(7):788-96.

2007

Trawler: de novo regulatory motif discovery pipeline for chromatin immunoprecipitation

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Systematic discovery of in vivo phosphorylation networks

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2007

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Mol Cell. 2007 Apr 13;26(1):51-62

2007

Ca2+ channel blockers reverse iron overload by a new mechanism via divalent metal transporter-1.

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2007

Modulation of the immunological synapse: a key to HIV-1 pathogenesis?

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Nat Rev Immunol. 2007 Apr;7(4):310-7.

2007

Quantitative phylogenetic assessment of microbial communities in diverse environments.

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Mol Cell. 2007 Jan 26;25(2):247-60.

2007

Cdkn1a deletion improves stem cell function and lifespan of mice with dysfunctional telomeres without accelerating cancer formation.

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2007

Direct monitoring of formation and dissociation of individual metal complexes by single-molecule fluorescence spectroscopy

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2006

Following the signal sequence from ribosomal tunnel exit to signal recognition particle

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2006

Individual cell migration serves as the driving force for optic vesicle evagination.

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2006

High-throughput RNAi screening by time-lapse imaging of live human cells

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Nat Methods. 2006 May;3(5):385-90

2006

Vaccinia virus-induced cell motility requires F11L-mediated inhibition of RhoA signaling

Valderrama F, Cordeiro JV, Schleich S, Frischknecht F, Way M

Science. 2006 Jan 20;311(5759):377-81

2005

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Nat Med. 2005 Dec;11(12):1322-9.

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A complex of N-WASP and WIP integrates signalling cascades that lead to actin polymerization

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Nat Cell Biol. 2000 Jul;2(7):441-8

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