Publications
2018
Eukaryotic Ribosome Assembly
Baßler J, Hurt E
Annu Rev Biochem. 2018 Dec 19. doi: 10.1146/annurev-biochem-013118-110817
2018
Suppressor mutations in Rpf2-Rrs1 or Rpl5 bypass the Cgr1 function for pre-ribosomal 5S RNP-rotation
Thoms M, Mitterer V, Kater L, Falquet L, Beckmann R, Kres...
Nat Commun. 2018 Oct 5;9(1):4094. doi: 10.1038/s41467-018-06660-w
2018
Assembly Kinetics of Vimentin Tetramers to Unit-Length Filaments: A Stopped-Flow Study
Mücke N, Kämmerer L, Winheim S, Kirmse R, Krieger J, Mild...
Biophys J. 2018 May 22;114(10):2408-2418. doi: 10.1016/j.bpj.2018.04.032
2018
Structure of the nuclear exosome captured on a maturing preribosome
Schuller JM, Falk S, Fromm L, Hurt E, Conti E
Science. 2018 Apr 13;360(6385):219-222. doi: 10.1126/science.aar5428
2017
Interdependent action of KH domain proteins Krr1 and Dim2 drive the 40S platform assembly
Sturm M, Cheng J, Baßler J, Beckmann R, Hurt E
Nat Commun. 2017 Dec 20;8(1):2213. doi: 10.1038/s41467-017-02199-4.
2017
Visualizing the Assembly Pathway of Nucleolar Pre-60S Ribosomes
Kater L, Thoms M, Barrio-Garcia C, Cheng J, Ismail S, Ahm...
Cell. 2017 Dec 14;171(7):1599-1610.e14. doi: 10.1016/j.cell.2017.11.039.
2017
Preribosomes escaping from the nucleus are caught during translation by cytoplasmic quality control
Sarkar A, Thoms M, Barrio-Garcia C, Thomson E, Flemming D...
Nat Struct Mol Biol. 2017 Dec;24(12):1107-1115. doi: 10.1038/nsmb.3495.
2017
Structural insights into the interaction of the nuclear exosome helicase Mtr4 with the preribosomal protein Nop53
Falk S, Tants JN, Basquin J, Thoms M, Hurt E, Sattler M, ...
RNA. 2017 Dec;23(12):1780-1787. doi: 10.1261/rna.062901.117.
2017
Reconstitution of the complete pathway of ITS2 processing at the pre-ribosome
Fromm L, Falk S, Flemming D, Schuller JM, Thoms M, Conti ...
Nat Commun. 2017 Nov 27;8(1):1787. doi: 10.1038/s41467-017-01786-9.
2017
Cryo-EM structure of a late pre-40S ribosomal subunit from Saccharomyces cerevisiae
Heuer A, Thomson E, Schmidt C, Berninghausen O, Becker T,...
Elife. 2017 Nov 20;6. pii: e30189. doi: 10.7554/eLife.30189.
2017
3.2-Å-resolution structure of the 90S preribosome before A1 pre-rRNA cleavage
Cheng J, Kellner N, Berninghausen O, Hurt E, Beckmann R
Nat Struct Mol Biol. 2017 Nov;24(11):954-964. doi: 10.1038/nsmb.3476.
2017
A short linear motif in scaffold Nup145C connects Y-complex with pre-assembled outer ring Nup82 complex
Teimer R, Kosinski J, von Appen A, Beck M, Hurt E
Nat Commun. 2017 Oct 24;8(1):1107. doi: 10.1038/s41467-017-01160-9.
2017
Eukaryotic ribosome assembly, transport and quality control
Peña C, Hurt E, Panse VG
Nat Struct Mol Biol. 2017 Sep 7;24(9):689-699. doi: 10.1038/nsmb.3454.
2017
Mpp10 represents a platform for the interaction of multiple factors within the 90S pre-ribosome
Sá-Moura B, Kornprobst M, Kharde S, Ahmed YL, Stier G, Ku...
PLoS One. 2017 Aug 16;12(8):e0183272. doi: 10.1371/journal.pone.0183272.
2017
A Puzzle of Life: Crafting Ribosomal Subunits
Kressler D, Hurt E, Baßler J
Trends Biochem Sci. 2017 Aug;42(8):640-654. doi: 10.1016/j.tibs.2017.05.005.
2017
Structural basis for 5'-ETS recognition by Utp4 at the early stages of ribosome biogenesis
Calviño FR, Kornprobst M, Schermann G, Birkle F, Wild K, ...
PLoS One. 2017 Jun 2;12(6):e0178752. doi: 10.1371/journal.pone.0178752.
2017
The nuclear pore complex: understanding its function through structural insight
Beck M, Hurt E
Nat Rev Mol Cell Biol. 2017 Feb;18(2):73-89. doi: 10.1038/nrm.2016.147.
2017
Interaction network of the ribosome assembly machinery from a eukaryotic thermophile
Baßler J, Ahmed YL, Kallas M, Kornprobst M, Calviño FR, G...
Protein Sci. 2017 Feb;26(2):327-342. doi: 10.1002/pro.3085.
2016
Ribosome-stalk biogenesis is coupled with recruitment of nuclear-export factor to the nascent 60S subunit
Sarkar A, Pech M, Thoms M, Beckmann R, Hurt E
Nat Struct Mol Biol. 2016 Dec;23(12):1074-1082. doi: 10.1038/nsmb.3312.
2016
Architecture of the 90S Pre-ribosome: A Structural View on the Birth of the Eukaryotic Ribosome
Kornprobst M, Turk M, Kellner N, Cheng J, Flemming D, Koš...
Cell. 2016 Jul 14;166(2):380-93. doi: 10.1016/j.cell.2016.06.014
2016
Molecular architecture of the inner ring scaffold of the human nuclear pore complex
Kosinski J, Mosalaganti S, von Appen A, Teimer R, DiGuili...
Science. 2016 Apr 15;352(6283):363-5. doi: 10.1126/science.aaf0643
2016
The K⁺-dependent GTPase Nug1 is implicated in the association of the helicase Dbp10 to the immature peptidyl transferase centre during ribosome maturation
Manikas RG, Thomson E, Thoms M, Hurt E
Nucleic Acids Res. 2016 Feb 29;44(4):1800-12. doi: 10.1093/nar/gkw045
2016
Developing genetic tools to exploit Chaetomium thermophilum for biochemical analyses of eukaryotic macromolecular assemblies
Kellner N, Schwarz J, Sturm M, Fernandez-Martinez J, Grie...
Sci Rep. 2016 Feb 11;6:20937. doi: 10.1038/srep20937
2016
Concerted removal of the Erb1-Ytm1 complex in ribosome biogenesis relies on an elaborate interface
Thoms M, Ahmed YL, Maddi K, Hurt E, Sinning I
Nucleic Acids Res. 2016 Jan 29;44(2):926-39. doi: 10.1093/nar/gkv1365
2016
Architecture of the Rix1-Rea1 checkpoint machinery during pre-60S-ribosome remodeling
Barrio-Garcia C, Thoms M, Flemming D, Kater L, Berninghau...
Nat Struct Mol Biol. 2016 Jan;23(1):37-44. doi: 10.1038/nsmb.3132
2015
Coordinated Ribosomal ITS2 RNA Processing by the Las1 Complex Integrating Endonuclease, Polynucleotide Kinase, and Exonuclease Activitie
Gasse L, Flemming D, Hurt E
Mol Cell. 2015 Dec 3;60(5):808-15. doi: 10.1016/j.molcel.2015.10.021
2015
Direct and high throughput (HT) interactions on the ribosomal surface by iRIA
Pesce E, Minici C, Baßler J, Hurt E, Degano M, Calamita P...
Sci Rep. 2015 Oct 21;5:15401. doi: 10.1038/srep15401
2015
Architecture of the fungal nuclear pore inner ring complex
Stuwe T, Bley CJ, Thierbach K, Petrovic S, Schilbach S, M...
Science. 2015 Oct 2;350(6256):56-64. doi: 10.1126/science.aac9176
2015
Linker Nups connect the nuclear pore complex inner ring with the outer ring and transport channel
Fischer J, Teimer R, Amlacher S, Kunze R, Hurt E
Nat Struct Mol Biol. 2015 Oct;22(10):774-81. doi: 10.1038/nsmb.3084
2015
The exosome is recruited to RNA substrates through specific adapter proteins
Thoms M, Thomson E, Baßler J, Gnädig M, Griesel S, Hurt E
Cell. 2015 Aug 27;162(5):1029-38. doi: 10.1016/j.cell.2015.07.060.
2015
Co-translational capturing of nascent ribosomal proteins by their dedicated chaperones
Pausch P, Singh U, Ahmed YL, Pillet B, Murat G, Altegoer ...
Nat Commun. 2015 Jun 26;6:7494. doi: 10.1038/ncomms8494
2015
Structural Characterization of the Chaetomium thermophilum TREX-2 Complex and its Interaction with the mRNA Nuclear Export Factor Mex67:Mtr2
Dimitrova L, Valkov E, Aibara S, Flemming D, McLaughlin S...
Structure. 2015 Jul 7;23(7):1246-57. doi: 10.1016/j.str.2015.05.002
2015
Structural characterization of the principal mRNA-export factor Mex67-Mtr2 from Chaetomium thermophilum
Aibara S, Valkov E, Lamers MH, Dimitrova L, Hurt E, Stewa...
Acta Crystallogr F Struct Biol Commun. 2015 Jul;71(Pt 7):876-88. doi: 10.1107/S2053230X15008766
2015
Towards understanding nuclear pore complex architecture and dynamics in the age of integrative structural analysis
Hurt E, Beck M
Curr Opin Cell Biol. 2015 Jun;34:31-8. doi: 10.1016/j.ceb.2015.04.009
2015
Coordinated ribosomal L4 protein assembly into the pre-ribosome is regulated by its eukaryote-specific extension
Stelter P, Huber FM, Kunze R, Flemming D, Hoelz A, Hurt E
Molecular Cell, April 30, 2015, doi: 10.1016/j.molcel.2015.03.029.
2015
Symportin 1 chaperones 5S RNP assembly during ribosome biogenesis by occupying an essential rRNA-binding site
Calviño FR, Kharde S, Ori A, Hendricks A, Wild K, Kressle...
Nat Commun. 2015 Apr 7;6:6510. doi: 10.1038/ncomms7510
2015
NTF2-like domain of Tap plays a critical role in cargo mRNA recognition and export
Katahira J, Dimitrova L, Imai Y, Hurt E
Nucleic Acids Res. 2015 Feb 18;43(3):1894-904. doi: 10.1093/nar/gkv039
2015
Structural basis for assembly and function of the Nup82 complex in the nuclear pore scaffold
Gaik M, Flemming D, von Appen A, Kastritis P, Mücke N, Fi...
J Cell Biol. 2015 Feb 2;208(3):283-97. doi: 10.1083/jcb.201411003
2014
An integrated approach for genome annotation of the eukaryotic thermophile Chaetomium thermophilum
Bock T, Chen WH, Ori A, Malik N, Silva-Martin N, Huerta-C...
Nucleic Acids Res. 2014 Dec 16;42(22):13525-33. doi: 10.1093/nar/gku1147
2014
A network of assembly factors is involved in remodeling rRNA elements during preribosome maturation
Bassler J, Paternoga H, Holdermann I, Thoms M, Granneman ...
J Cell Biol. 2014 Nov 24;207(4):481-98. doi: 10.1083/jcb.201408111. Epub 2014 Nov 17
2014
Functional reconstitution of mitochondrial Fe/S cluster synthesis on Isu1 reveals the involvement of ferredoxin
Webert H, Freibert SA, Gallo A, Heidenreich T, Linne U, A...
Nat Commun. 2014 Oct 31;5:5013. doi: 10.1038/ncomms6013
2014
Dominant Rio1 kinase/ATPase catalytic mutant induces trapping of late pre-40S biogenesis factors in 80S-like ribosomes
Ferreira-Cerca S, Kiburu I, Thomson E, LaRonde N, Hurt E
Nucleic Acids Res. 2014 Jul;42(13):8635-47. doi: 10.1093/nar/gku542. Epub 2014 Jun 19
2014
Utilizing the Dyn2 dimerization-zipper as a tool to probe NPC structure and function
Flemming D, Stelter P1, Hurt E
Methods Cell Biol. 2014;122:99-115. doi: 10.1016/B978-0-12-417160-2.00005-9
2014
A pulse-chase epitope labeling to study cellular dynamics of newly synthesized proteins: a novel strategy to characterize NPC biogenesis and ribosome maturation/export
Stelter P, Hurt E
Methods Cell Biol. 2014;122:147-63. doi: 10.1016/B978-0-12-417160-2.00007-2
2014
60S ribosome biogenesis requires rotation of the 5S ribonucleoprotein particle
Leidig C, Thoms M, Holdermann I, Bradatsch B, Berninghaus...
Nat Commun. 2014 Mar 24;5:3491. doi: 10.1038/ncomms4491
2014
Evidence for an evolutionary relationship between the large adaptor nucleoporin Nup192 and karyopherins
Stuwe T, Lin DH, Collins LN, Hurt E, Hoelz A.
Proc Natl Acad Sci U S A. 2014 Feb 18;111(7):2530-5.
2013
Coupled GTPase and remodelling ATPase activities form a checkpoint for ribosome export
Matsuo Y, Granneman S, Thoms M, Manikas RG, Tollervey D, ...
Nature. 2013 November 17;published online 17 November 2013, doi:10.1038/nature12731
2013
Eukaryotic ribosome biogenesis at a glance
Thomson E, Ferreira-Cerca S, Hurt E
J Cell Sci.
2013
Protein interfaces of the conserved Nup84 complex from Chaetomium thermophilum shown by crosslinking mass spectrometry and electron microscopy
Thierbach, K., von Appen, A., Thoms, M., Beck, M., Flemmi...
Structure. 2013 Sep 3;21(9):1672-82. doi: 10.1016/j.str.2013.07.004
2013
Structural basis of histone H2A-H2B recognition by the essential chaperone FACT
Hondele M, Stuwe T, Hassler M, Halbach F, Bowman A, Zhang...
Nature.
2013
New twist to nuclear import: When two travel together
Bange G, Murat G, Sinning I, Hurt E, Kressler D
Commun Integr Biol.
2013
Structural basis for cooperativity of CRM1 export complex formation
Monecke T, Haselbach D, Voß B, Russek A, Neumann P, Thoms...
Proc Natl Acad Sci U S A.
2013
Consistent mutational paths predict eukaryotic thermostability
van Noort V, Bradatsch B, Arumugam M, Amlacher S, Bange G...
BMC Evol Biol. 2013 Jan 10;13:7. doi: 10.1186/1471-2148-13-7.
2013
Rrp5p, Noc1p and Noc2p form a protein module which is part of early large ribosomal subunit precursors in S. cerevisiae
Hierlmeier T, Merl J, Sauert M, Perez-Fernandez J, Schult...
Nucleic Acids Res. 2013 Jan;41(2):1191-210. doi: 10.1093/nar/gks1056
2013
Structural characterization of a eukaryotic chaperone--the ribosome-associated complex
Leidig C, Bange G, Kopp J, Amlacher S, Aravind A, Wickles...
Nat Struct Mol Biol. 2013 Jan;20(1):23-8. doi: 10.1038/nsmb.2447
2012
The conserved Bud20 zinc finger protein is a new component of the ribosomal 60S subunit export machinery
Bassler J, Klein I, Schmidt C, Kallas M, Thomson E, Wagne...
Mol Cell Biol.
2012
Structure of the pre-60S ribosomal subunit with nuclear export factor Arx1 bound at the exit tunnel
Bradatsch B, Leidig C, Granneman S, Gnädig M, Tollervey D...
Nat Struct Mol Biol.
2012
ATPase-dependent role of the atypical kinase Rio2 on the evolving pre-40S ribosomal subunit
Ferreira-Cerca S, Sagar V, Schäfer T, Diop M, Wesseling A...
Nat Struct Mol Biol.
2012
Monitoring Spatiotemporal Biogenesis of Macromolecular Assemblies by Pulse-chase Epitope Labeling
Stelter P, Kunze R, Radwan M, Thomson E, Thierbach K, Tho...
Mol Cell.
2012
Synchronizing Nuclear Import of Ribosomal Proteins with Ribosome Assembly
Kressler D, Bange G, Ogawa Y, Stjepanovic G, Bradatsch B,...
Science.
2012
Functional and structural characterisation of the mammalian TREX-2 complex that links transcription with nuclear mRNA export
Jani D, Lutz S, Hurt E, Laskey RA, Stewart M, Wickramasin...
Nucleic Acids Res.
2012
Structural basis for the assembly and nucleic acid binding of the TREX-2 transcription-export complex
Ellisdon AM, Dimitrova L, Hurt E, Stewart M
Nat Struct Mol Biol.
2012
Analysis of the yeast nucleoporin Nup188 reveals a conserved S-like structure with similarity to karyopherins
Flemming D, Devos DP, Schwarz J, Amlacher S, Lutzmann M, ...
J Struct Biol. 2012 Jan;177(1):99-105. doi: 10.1016/j.jsb.2011.11.008. Epub 2011 Nov 22.
2012
The power of AAA- ATPases on the road of pre-60S ribosome maturation - molecular machines that strip pre-ribosomal particles
Kressler D, Hurt E, Bergler H, Bassler J
Biochim Biophys Acta.
2011
Structural basis for the molecular evolution of SRP-GTPase activation by protein
Bange G, Kümmerer N, Grudnik P, Lindner R, Petzold G, Kre...
Nat Struct Mol Biol. 2011 Nov 6;18(12)
2011
Probing the FG repeat network of nucleoporins defines structural and functional features of the nuclear pore complex
Stelter P, Kunze R, Fischer J, Hurt E
J Cell Biol. 2011 Oct 17;195(2):183-92. doi: 10.1083/jcb.201105042. Epub 2011 Oct 10.
2011
Insight into structure and assembly of the nuclear pore complex by utilizing the genome of a eukaryotic thermophile
Amlacher S, Sarges P, Flemming D, van Noort V, Kunze R, D...
Cell 146(2):277-289. doi: 10.1016/j.cell.2011.06.039
2011
Linking gene regulation to mRNA production and export
Rodríguez-Navarro S, Hurt E
Curr Opin Cell Biol. 2011 Jun;23(3):302-9. doi: 10.1016/j.ceb.2010.12.002. Epub 2011 Jan 11.
2010
Precise mapping of subunits in multiprotein complexes by a versatile electron microscopy label
Flemming D, Thierbach K, Stelter P, Böttcher B, Hurt E
Nat Struct Mol Biol. 2010 Jun;17(6):775-8
2010
The AAA-ATPase Rea1 drives removal of biogenesis factors during multiple stages of 60S ribosome assembly
Bassler J, Kallas M, Pertschy B, Ulbrich C, Thoms M, Hurt E
Mol Cell. 2010 Jun 11;38(5):712-21
2010
Driving ribosome assembly
Kressler D, Hurt E, Bassler J
Biochim Biophys Acta. 2010 Jun;1803(6):673-83
2010
Structural basis for assembly and activation of the heterotetrameric SAGA histone H2B deubiquitinase module
Köhler A, Zimmerman E, Schneider M, Hurt E, Zheng N
Cell. 2010 May 14;141(4):606-17
2010
The structure of Get4 reveals an alpha-solenoid fold adapted for multiple interactions in tail-anchored protein biogenesis
Bozkurt G, Wild K, Amlacher S, Hurt E, Dobberstein B, Sin...
FEBS Lett. 2010 Apr 16;584(8):1509-14
2010
Gene regulation by nucleoporins and links to cancer
Köhler A, Hurt E
Mol Cell. 2010 Apr 9;38(1):6-15
2010
Structural basis for the interaction between yeast Spt-Ada-Gcn5 acetyltransferase (SAGA) complex components Sgf11 and Sus1
Ellisdon AM, Jani D, Köhler A, Hurt E, Stewart M
J Biol Chem. 2010 Feb 5;285(6):3850-6
2009
Structural insights into tail-anchored protein binding and membrane insertion by Get3
Bozkurt G, Stjepanovic G, Vilardi F, Amlacher S, Wild K, ...
Proc Natl Acad Sci U S A. 2009 Dec 15;106(50):21131-6
2009
Purification of nuclear poly(A)-binding protein Nab2 reveals association with the yeast transcriptome and a messenger ribonucleoprotein core structure
Batisse J, Batisse C, Budd A, Böttcher B, Hurt E
J Biol Chem. 2009 Dec 11;284(50):34911-7
2009
RNA helicase Prp43 and its co-factor Pfa1 promote 20 to 18 S rRNA processing catalyzed by the endonuclease Nob1
Pertschy B, Schneider C, Gnädig M, Schäfer T, Tollervey D...
J Biol Chem. 2009 Dec 11;284(50):35079-91
2009
Mechanochemical Removal of Ribosome Biogenesis Factors from Nascent 60S Ribosomal Subunits
Ulbrich C, Diepholz M, Bassler J, Kressler D, Pertschy B,...
Cell. 2009 Sep 4;138(5):911-22
2009
Cell biology: Arrest by ribosome.
Ferreira-Cerca S, Hurt E.
Nature. 2009 May 7;459(7243):46-7.
2009
Two structurally distinct domains of the nucleoporin Nup170 cooperate to tether a subset of nucleoporins to nuclear pores
Flemming D, Sarges P, Stelter P, Hellwig A, Böttcher B, H...
J Cell Biol. 2009 May 4;185(3):387-95
2009
Mutational uncoupling of the role of Sus1 in nuclear pore complex targeting of an mRNA export complex and histone H2B deubiquitination.
Klöckner C, Schneider M, Lutz S, Jani D, Kressler D, Stew...
J Biol Chem. 2009 May 1;284(18):12049-56
2009
Linear ubiquitin fusion to Rps31 and its subsequent cleavage 1 are required for the efficient production and functional integrity of 40S ribosomal subunits.
Lacombe T, García-Gómez JJ, de la Cruz J, Roser D, Hurt E...
Mol Microbiol. 2009 Apr;72(1):69-84
2009
Sus1, Cdc31 and the Sac3 CID region form a conserved interaction platform that promotes nuclear pore association and mRNA export.
Jani D, Lutz S, Marshall NJ, Fischer T, Köhler A, Ellisdo...
Mol Cell. 2009 Mar 27;33(6):727-37.
2009
Sem1 is a functional component of the nuclear pore complex associated mRNA export machinery.
Faza MB, Kemmler S, Jimeno S, González-Aguilera C, Aguile...
J Cell Biol. 2009 Mar 23;184(6):833-46
2009
The adaptor Aly and co-adaptor Thoc5 function in Tap-p15 mediated nuclear export of HSP70 mRNA.
Katahira J, Inoue H, Hurt E, Yoneda Y.
EMBO J. 2009 Mar 4;28(5):556-67
2009
An endoribonuclease functionally linked to perinuclear mRNP quality control associates with the nuclear pore complexes.
Skruzný M, Schneider C, Rácz A, Weng J, Tollervey D, Hurt E.
PLoS Biol. 2009 Jan 6;7(1):e8
2009
A toxic nucleoporin mutant induces abarrent nucleoporin foci in the cytoplasm.
Dirk Flemming, Philipp Sarges, Philipp Stelter, Andrea He...
J. Cell Biol. 185, 387-396.
2009
Nucleus-Specific and Cell Cycle-Regulated Degradation of MAPK Scaffold Protein Ste5 Contributes to the Control of Signaling Competence.
Garrenton LS, Braunwarth A, Irniger S, Hurt E, Künzler M,...
Mol Cell Biol. 2009 Jan;29(2):582-601
2008
The inner nuclear membrane protein Src1 associates with subtelomeric genes and alters their regulated gene expression
Grund SE, Fischer T, Cabal GG, Antúnez O, Pérez-Ortín JE,...
J Cell Biol. 2008 Sep 8;182(5):897-910
2008
Membrane curvature induced by Arf1-GTP is essential for vesicle formation
Beck R, Sun Z, Adolf F, Rutz C, Bassler J, Wild K, Sinnin...
Proc Natl Acad Sci U S A. 2008 Aug 19;105(33):11731-6
2008
The AAA ATPase Rix7 powers progression of ribosome biogenesis by stripping Nsa1 from pre-60S particles
Kressler D, Roser D, Pertschy B, Hurt E
J Cell Biol. 2008 Jun 16;181(6):935-44
2008
Yeast Ataxin-7 links histone deubiquitination with gene gating and mRNA export
Köhler A, Schneider M, Cabal GG, Nehrbass U, Hurt E.
Nat Cell Biol. 2008 Jun;10(6):707-15
2008
Structural basis of the nic96 subcomplex organization in the nuclear pore channel
Schrader N, Stelter P, Flemming D, Kunze R, Hurt E, Vette...
Mol Cell. 2008 Jan 18;29(1):46-55.
2008
A versatile interaction platform on the Mex67-Mtr2 receptor creates an overlap between mRNA and ribosome export
Yao W, Lutzmann M, Hurt E
EMBO J. 2008 Jan 9;27(1):6-16
2008
“Der Kernporenkomplex oder das Tor zur Welt des Zytoplasmas” im Jahrbuch 2007 der Deutschen Akademie der Naturforscher Leopoldina
Hurt E
Leopoldina 53, 457-460 (2008)
2007
Exporting RNA from the nucleus to the cytoplasm
Köhler A, Hurt E.
Nat Rev Mol Cell Biol. 2007 Oct;8(10):761-73.
2007
The crystal structure of Ebp1 reveals a methionine aminopeptidase fold as binding platform for multiple interactions
Kowalinski E, Bange G, Bradatsch B, Hurt E, Wild K, Sinni...
FEBS Lett. 2007 Sep 18;581(23):4450-4
2007
Arx1 functions as alternative nuclear export receptor for the 60S pre-ribosomal subunit
Bradatsch B, Katahira J, Kowalinsk Ei, Bange G, Yao W, Se...
Mol Cell. 2007 Sep 7;27(5):767-79.
2007
Molecular basis for the functional interaction of dynein light chain with the nuclear pore complex
Stelter P, Kunze R, Flemming D, Höpfner D, Diepholz M, Ph...
Nat Cell Biol. 2007 Jul;9(7):788-96.
2007
Adjunct duties for karyopherins: regulating septin sumoylation
Panse VG, Hurt E
Dev Cell. 2007 May;12(5):669-70
2007
Nuclear export of ribosomal 60S subunits by the general mRNA export receptor Mex67-Mtr2
Yao W, Roser D, Köhler A, Bradatsch B, Bassler J, Hurt E
Mol Cell. 2007 Apr 13;26(1):51-62
2006
Formation and nuclear export of preribosomes are functionally linked to the small-ubiquitin-related modifier pathway
Panse VG, Kressler D, Pauli A, Petfalski E, Gnädig M, Tol...
Traffic. 2006 Oct;7(10):1311-21
2006
The mRNA export factor Sus1 is involved in Spt/Ada/Gcn5 acetyltransferase-mediated H2B deubiquitinylation through its interaction with Ubp8 and Sgf11
Köhler A, Pascual-García P, Llopis A, Zapater M, Posas F,...
Mol Biol Cell. 2006 Oct;17(10):4228-36
2006
The NUG1 GTPase reveals and N-terminal RNA-binding domain that is essential for association with 60 S pre-ribosomal particles
Bassler J, Kallas M, Hurt E
J Biol Chem. 2006 Aug 25;281(34):24737-44
2006
TOR regulates late steps of ribosome maturation in the nucleoplasm via Nog1 in response to nutrients
Honma Y, Kitamura A, Shioda R, Maruyama H, Ozaki K, Oda Y...
EMBO J. 2006 Aug 23;25(16):3832-42
2006
Hrr25-dependent phosphorylation state regulates organization of the pre-40S subunit.
Schäfer T, Maco B, Petfalski E, Tollervey D, Böttcher B, ...
"Nature. 2006 Jun 1;441(7093):651-5."
2006
Coordinated nuclear import of RNA polymerase III subunits
Hardeland U, Hurt E
Traffic. 2006 Apr;7(4):465-73
2006
Molecular Analysis of SAGA Mediated Gene Gating In Yeast
Cabal G, Rodrigez-Navarro S, Genevesio A, Olivo-Marin JC,...
Nature 441, 770-773 (2006)
2006
A round of phosphorylation/de-phosphorylation triggers maturation of the pre-ribosomal 40S subunit
Schäfer T, Maco B, Petfalski E, Tollervey D, Boettcher B,...
Nature 441, 651-655 (2006)