Non-coding RNA in hepatocellular carcinoma: Mechanisms, biomarkers and therapeutic targets
2017
Authors: Klingenberg M, Matsuda A, Diederichs S, Patel T
CellNetworks People: Diederichs Sven
Journal: J Hepatol. 2017 Sep;67(3):603-618. doi: 10.1016/j.jhep.2017.04.009

The majority of the human genome is not translated into proteins but can be transcribed into RNA. Even though the resulting non-coding RNAs (ncRNAs) do not encode for proteins, they contribute to diseases such as cancer. Here, we review examples of the functions of ncRNAs in liver cancer and their potential use for the detection and treatment of liver cancer.